| Full name: RAS like family 11 member B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 65997 | HGNC ID: HGNC:23804 | Ensembl Gene: ENSG00000128045 | OMIM ID: 612404 |
| Drug and gene relationship at DGIdb | |||
Expression of RASL11B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASL11B | 65997 | 219142_at | 0.7189 | 0.0286 | |
| GSE20347 | RASL11B | 65997 | 219142_at | 0.6250 | 0.0000 | |
| GSE23400 | RASL11B | 65997 | 219142_at | 0.0777 | 0.0454 | |
| GSE26886 | RASL11B | 65997 | 234102_at | 0.1194 | 0.2229 | |
| GSE29001 | RASL11B | 65997 | 219142_at | 0.4801 | 0.0405 | |
| GSE38129 | RASL11B | 65997 | 219142_at | 0.5785 | 0.0011 | |
| GSE45670 | RASL11B | 65997 | 219142_at | 0.7033 | 0.0008 | |
| GSE63941 | RASL11B | 65997 | 219142_at | -3.8287 | 0.0000 | |
| GSE77861 | RASL11B | 65997 | 219142_at | 0.4438 | 0.0596 | |
| GSE97050 | RASL11B | 65997 | A_23_P69738 | 0.0414 | 0.9394 | |
| SRP007169 | RASL11B | 65997 | RNAseq | 4.8224 | 0.0000 | |
| SRP008496 | RASL11B | 65997 | RNAseq | 4.3680 | 0.0000 | |
| SRP064894 | RASL11B | 65997 | RNAseq | 3.0378 | 0.0000 | |
| SRP133303 | RASL11B | 65997 | RNAseq | 2.2560 | 0.0000 | |
| SRP159526 | RASL11B | 65997 | RNAseq | 2.7846 | 0.0002 | |
| SRP219564 | RASL11B | 65997 | RNAseq | 1.1871 | 0.0437 | |
| TCGA | RASL11B | 65997 | RNAseq | 0.2760 | 0.2219 |
Upregulated datasets: 6; Downregulated datasets: 1.
Survival by RASL11B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RASL11B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASL11B | 65997 | 4 | 11 | 15 | |
| GSE20123 | RASL11B | 65997 | 3 | 11 | 16 | |
| GSE43470 | RASL11B | 65997 | 0 | 14 | 29 | |
| GSE46452 | RASL11B | 65997 | 1 | 36 | 22 | |
| GSE47630 | RASL11B | 65997 | 1 | 18 | 21 | |
| GSE54993 | RASL11B | 65997 | 7 | 0 | 63 | |
| GSE54994 | RASL11B | 65997 | 2 | 10 | 41 | |
| GSE60625 | RASL11B | 65997 | 0 | 0 | 11 | |
| GSE74703 | RASL11B | 65997 | 0 | 12 | 24 | |
| GSE74704 | RASL11B | 65997 | 2 | 6 | 12 | |
| TCGA | RASL11B | 65997 | 16 | 30 | 50 |
Total number of gains: 36; Total number of losses: 148; Total Number of normals: 304.
Somatic mutations of RASL11B:
Generating mutation plots.
Highly correlated genes for RASL11B:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASL11B | GGT7 | 0.750545 | 3 | 0 | 3 |
| RASL11B | TMEM9 | 0.731448 | 4 | 0 | 3 |
| RASL11B | ATG16L1 | 0.71277 | 3 | 0 | 3 |
| RASL11B | C4orf46 | 0.705217 | 3 | 0 | 3 |
| RASL11B | EFNB1 | 0.705006 | 5 | 0 | 5 |
| RASL11B | EN1 | 0.69112 | 3 | 0 | 3 |
| RASL11B | TFE3 | 0.690039 | 3 | 0 | 3 |
| RASL11B | ZNF133 | 0.689027 | 3 | 0 | 3 |
| RASL11B | ENPP7 | 0.687768 | 3 | 0 | 3 |
| RASL11B | SMYD4 | 0.686838 | 3 | 0 | 3 |
| RASL11B | PEAR1 | 0.684104 | 3 | 0 | 3 |
| RASL11B | CECR2 | 0.683315 | 4 | 0 | 4 |
| RASL11B | MAGEL2 | 0.681823 | 3 | 0 | 3 |
| RASL11B | MEST | 0.681722 | 4 | 0 | 4 |
| RASL11B | ADAM21 | 0.680767 | 4 | 0 | 3 |
| RASL11B | SDCCAG8 | 0.675446 | 4 | 0 | 3 |
| RASL11B | LONP1 | 0.66545 | 6 | 0 | 5 |
| RASL11B | ANKRD39 | 0.661427 | 4 | 0 | 3 |
| RASL11B | C4BPA | 0.660962 | 3 | 0 | 3 |
| RASL11B | GPR180 | 0.660183 | 4 | 0 | 3 |
For details and further investigation, click here
