| Full name: torsin family 3 member A | Alias Symbol: FLJ22345|ADIR2 | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 64222 | HGNC ID: HGNC:11997 | Ensembl Gene: ENSG00000186283 | OMIM ID: 607555 |
| Drug and gene relationship at DGIdb | |||
Expression of TOR3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOR3A | 64222 | 218459_at | 0.8892 | 0.0726 | |
| GSE20347 | TOR3A | 64222 | 218459_at | 1.0781 | 0.0000 | |
| GSE23400 | TOR3A | 64222 | 218459_at | 0.6643 | 0.0000 | |
| GSE26886 | TOR3A | 64222 | 218459_at | 1.9811 | 0.0000 | |
| GSE29001 | TOR3A | 64222 | 218459_at | 0.9342 | 0.0001 | |
| GSE38129 | TOR3A | 64222 | 218459_at | 1.1221 | 0.0000 | |
| GSE45670 | TOR3A | 64222 | 218459_at | 0.6907 | 0.0011 | |
| GSE53622 | TOR3A | 64222 | 51709 | 0.1762 | 0.0159 | |
| GSE53624 | TOR3A | 64222 | 75258 | 1.0258 | 0.0000 | |
| GSE63941 | TOR3A | 64222 | 218459_at | -0.4326 | 0.3338 | |
| GSE77861 | TOR3A | 64222 | 218459_at | 1.3835 | 0.0003 | |
| GSE97050 | TOR3A | 64222 | A_33_P3247403 | 0.4304 | 0.2499 | |
| SRP007169 | TOR3A | 64222 | RNAseq | 1.0163 | 0.0036 | |
| SRP008496 | TOR3A | 64222 | RNAseq | 1.6385 | 0.0000 | |
| SRP064894 | TOR3A | 64222 | RNAseq | 0.8983 | 0.0000 | |
| SRP133303 | TOR3A | 64222 | RNAseq | 0.7838 | 0.0001 | |
| SRP159526 | TOR3A | 64222 | RNAseq | 1.5136 | 0.0000 | |
| SRP193095 | TOR3A | 64222 | RNAseq | 0.6593 | 0.0000 | |
| SRP219564 | TOR3A | 64222 | RNAseq | 0.7415 | 0.0589 | |
| TCGA | TOR3A | 64222 | RNAseq | 0.2092 | 0.0010 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by TOR3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOR3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOR3A | 64222 | 12 | 0 | 18 | |
| GSE20123 | TOR3A | 64222 | 12 | 0 | 18 | |
| GSE43470 | TOR3A | 64222 | 9 | 1 | 33 | |
| GSE46452 | TOR3A | 64222 | 3 | 1 | 55 | |
| GSE47630 | TOR3A | 64222 | 14 | 0 | 26 | |
| GSE54993 | TOR3A | 64222 | 0 | 6 | 64 | |
| GSE54994 | TOR3A | 64222 | 15 | 0 | 38 | |
| GSE60625 | TOR3A | 64222 | 0 | 0 | 11 | |
| GSE74703 | TOR3A | 64222 | 8 | 1 | 27 | |
| GSE74704 | TOR3A | 64222 | 5 | 0 | 15 | |
| TCGA | TOR3A | 64222 | 40 | 3 | 53 |
Total number of gains: 118; Total number of losses: 12; Total Number of normals: 358.
Somatic mutations of TOR3A:
Generating mutation plots.
Highly correlated genes for TOR3A:
Showing top 20/1573 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOR3A | YDJC | 0.762821 | 5 | 0 | 4 |
| TOR3A | CENPL | 0.762082 | 5 | 0 | 5 |
| TOR3A | JTB | 0.754068 | 10 | 0 | 10 |
| TOR3A | SAC3D1 | 0.743316 | 10 | 0 | 10 |
| TOR3A | PSMB4 | 0.741631 | 10 | 0 | 9 |
| TOR3A | DHRS13 | 0.739249 | 3 | 0 | 3 |
| TOR3A | RIOK1 | 0.737176 | 5 | 0 | 5 |
| TOR3A | COLGALT1 | 0.735662 | 9 | 0 | 9 |
| TOR3A | APMAP | 0.733958 | 9 | 0 | 9 |
| TOR3A | RFC4 | 0.731094 | 11 | 0 | 11 |
| TOR3A | STARD7 | 0.725439 | 10 | 0 | 10 |
| TOR3A | TP53I13 | 0.720351 | 4 | 0 | 4 |
| TOR3A | PARP1 | 0.71984 | 11 | 0 | 9 |
| TOR3A | HOXB7 | 0.717947 | 10 | 0 | 10 |
| TOR3A | ITPRIPL1 | 0.716103 | 3 | 0 | 3 |
| TOR3A | MTERF3 | 0.715522 | 8 | 0 | 8 |
| TOR3A | FUS | 0.714589 | 9 | 0 | 9 |
| TOR3A | ZC3HAV1L | 0.714366 | 4 | 0 | 4 |
| TOR3A | DESI2 | 0.712683 | 10 | 0 | 10 |
| TOR3A | CMSS1 | 0.712603 | 5 | 0 | 5 |
For details and further investigation, click here
