OSBPL11

 

Full name: oxysterol binding protein like 11 Alias Symbol: ORP-11|ORP11|FLJ13012|FLJ13164
Type: protein-coding gene Cytoband: 3q21.2
Entrez ID: 114885 HGNC ID: HGNC:16397 Ensembl Gene: ENSG00000144909 OMIM ID: 606739
Drug and gene relationship at DGIdb

 

Expression of OSBPL11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OSBPL11 114885 218304_s_at 0.4717 0.1658
GSE20347 OSBPL11 114885 218304_s_at 0.1769 0.3526
GSE23400 OSBPL11 114885 218304_s_at 0.2129 0.0042
GSE26886 OSBPL11 114885 218304_s_at 0.5289 0.1181
GSE29001 OSBPL11 114885 218304_s_at 0.5365 0.1565
GSE38129 OSBPL11 114885 218304_s_at 0.2324 0.0876
GSE45670 OSBPL11 114885 218304_s_at 0.2490 0.0335
GSE53622 OSBPL11 114885 773 -0.0268 0.6875
GSE53624 OSBPL11 114885 773 0.0626 0.3410
GSE63941 OSBPL11 114885 218304_s_at 0.2370 0.5433
GSE77861 OSBPL11 114885 218304_s_at 0.2032 0.6790
GSE97050 OSBPL11 114885 A_23_P6914 0.2863 0.7802
SRP007169 OSBPL11 114885 RNAseq 0.1577 0.6637
SRP008496 OSBPL11 114885 RNAseq 0.4416 0.0438
SRP064894 OSBPL11 114885 RNAseq 0.0135 0.9510
SRP133303 OSBPL11 114885 RNAseq 0.5319 0.0001
SRP159526 OSBPL11 114885 RNAseq -0.0113 0.9707
SRP193095 OSBPL11 114885 RNAseq 0.1469 0.1743
SRP219564 OSBPL11 114885 RNAseq 0.0345 0.9089
TCGA OSBPL11 114885 RNAseq 0.1861 0.0044

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by OSBPL11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of OSBPL11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OSBPL11 114885 17 0 13
GSE20123 OSBPL11 114885 17 0 13
GSE43470 OSBPL11 114885 20 0 23
GSE46452 OSBPL11 114885 14 5 40
GSE47630 OSBPL11 114885 17 4 19
GSE54993 OSBPL11 114885 2 7 61
GSE54994 OSBPL11 114885 31 3 19
GSE60625 OSBPL11 114885 0 6 5
GSE74703 OSBPL11 114885 17 0 19
GSE74704 OSBPL11 114885 13 0 7
TCGA OSBPL11 114885 55 6 35

Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.  

 

Somatic mutations of OSBPL11:

 

Generating mutation plots.

 

Highly correlated genes for OSBPL11:

 

Showing top 20/89 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OSBPL11TANK0.764056303
OSBPL11ARHGAP210.70055303
OSBPL11FABP60.694521403
OSBPL11MDC10.675167303
OSBPL11VKORC1L10.673329303
OSBPL11CCL260.662928303
OSBPL11ZSCAN5A0.659548403
OSBPL11COQ50.658564303
OSBPL11CECR20.657474403
OSBPL11EDEM30.655262605
OSBPL11NID20.642518403
OSBPL11TMEM1820.642183404
OSBPL11C19orf530.639163403
OSBPL11PIK3R40.63505912010
OSBPL11TTC50.617508303
OSBPL11MED200.611853605
OSBPL11CHP20.611428503
OSBPL11NPL0.60933503
OSBPL11WRAP730.604972704
OSBPL11TIMMDC10.604969604

For details and further investigation, click here