| Full name: dynein heavy chain domain 1 | Alias Symbol: FLJ32752|FLJ46184|FLJ35709|DKFZp686J0796 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 144132 | HGNC ID: HGNC:26532 | Ensembl Gene: ENSG00000179532 | OMIM ID: 617277 |
| Drug and gene relationship at DGIdb | |||
Expression of DNHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNHD1 | 144132 | 232240_at | 0.0552 | 0.8656 | |
| GSE26886 | DNHD1 | 144132 | 232240_at | 0.2117 | 0.0672 | |
| GSE45670 | DNHD1 | 144132 | 232240_at | 0.1837 | 0.0905 | |
| GSE53622 | DNHD1 | 144132 | 30126 | -0.1947 | 0.0333 | |
| GSE53624 | DNHD1 | 144132 | 30126 | -0.7016 | 0.0000 | |
| GSE63941 | DNHD1 | 144132 | 232240_at | 0.5741 | 0.0087 | |
| GSE77861 | DNHD1 | 144132 | 232240_at | 0.1212 | 0.3514 | |
| GSE97050 | DNHD1 | 144132 | A_32_P360193 | -0.1132 | 0.6846 | |
| SRP007169 | DNHD1 | 144132 | RNAseq | 1.5118 | 0.0225 | |
| SRP064894 | DNHD1 | 144132 | RNAseq | 0.3516 | 0.2330 | |
| SRP133303 | DNHD1 | 144132 | RNAseq | -0.3960 | 0.0140 | |
| SRP159526 | DNHD1 | 144132 | RNAseq | 0.0327 | 0.9257 | |
| SRP193095 | DNHD1 | 144132 | RNAseq | 0.5103 | 0.0099 | |
| SRP219564 | DNHD1 | 144132 | RNAseq | 0.2619 | 0.4709 | |
| TCGA | DNHD1 | 144132 | RNAseq | -0.1333 | 0.2665 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DNHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNHD1 | 144132 | 1 | 11 | 18 | |
| GSE20123 | DNHD1 | 144132 | 1 | 11 | 18 | |
| GSE43470 | DNHD1 | 144132 | 1 | 8 | 34 | |
| GSE46452 | DNHD1 | 144132 | 7 | 8 | 44 | |
| GSE47630 | DNHD1 | 144132 | 2 | 12 | 26 | |
| GSE54993 | DNHD1 | 144132 | 3 | 1 | 66 | |
| GSE54994 | DNHD1 | 144132 | 2 | 12 | 39 | |
| GSE60625 | DNHD1 | 144132 | 0 | 0 | 11 | |
| GSE74703 | DNHD1 | 144132 | 1 | 6 | 29 | |
| GSE74704 | DNHD1 | 144132 | 0 | 8 | 12 | |
| TCGA | DNHD1 | 144132 | 9 | 38 | 49 |
Total number of gains: 27; Total number of losses: 115; Total Number of normals: 346.
Somatic mutations of DNHD1:
Generating mutation plots.
Highly correlated genes for DNHD1:
Showing top 20/184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNHD1 | GPS2 | 0.776955 | 3 | 0 | 3 |
| DNHD1 | CRYBB2 | 0.770669 | 3 | 0 | 3 |
| DNHD1 | KRTAP19-7 | 0.768915 | 3 | 0 | 3 |
| DNHD1 | CPLX1 | 0.760389 | 4 | 0 | 3 |
| DNHD1 | BARHL1 | 0.736139 | 3 | 0 | 3 |
| DNHD1 | COX19 | 0.729126 | 3 | 0 | 3 |
| DNHD1 | PRKACA | 0.728906 | 3 | 0 | 3 |
| DNHD1 | PACS1 | 0.727205 | 3 | 0 | 3 |
| DNHD1 | CNTD1 | 0.725607 | 3 | 0 | 3 |
| DNHD1 | TRAF7 | 0.720675 | 3 | 0 | 3 |
| DNHD1 | SLC6A9 | 0.719649 | 3 | 0 | 3 |
| DNHD1 | POLR3D | 0.718541 | 3 | 0 | 3 |
| DNHD1 | SORBS3 | 0.711745 | 3 | 0 | 3 |
| DNHD1 | SMARCD1 | 0.704635 | 4 | 0 | 4 |
| DNHD1 | PLIN4 | 0.696652 | 3 | 0 | 3 |
| DNHD1 | TADA1 | 0.696635 | 3 | 0 | 3 |
| DNHD1 | AFTPH | 0.695198 | 3 | 0 | 3 |
| DNHD1 | B3GAT2 | 0.688885 | 3 | 0 | 3 |
| DNHD1 | PCGF2 | 0.684587 | 4 | 0 | 3 |
| DNHD1 | C9orf16 | 0.68382 | 3 | 0 | 3 |
For details and further investigation, click here
