| Full name: centromere protein T | Alias Symbol: FLJ13111|CENP-T | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 80152 | HGNC ID: HGNC:25787 | Ensembl Gene: ENSG00000102901 | OMIM ID: 611510 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CENPT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPT | 80152 | 218148_at | 0.3227 | 0.3264 | |
| GSE20347 | CENPT | 80152 | 218148_at | 0.3074 | 0.0191 | |
| GSE23400 | CENPT | 80152 | 218148_at | 0.3427 | 0.0000 | |
| GSE26886 | CENPT | 80152 | 218148_at | 0.0839 | 0.6180 | |
| GSE29001 | CENPT | 80152 | 218148_at | -0.0200 | 0.9192 | |
| GSE38129 | CENPT | 80152 | 218148_at | 0.2338 | 0.0452 | |
| GSE45670 | CENPT | 80152 | 218148_at | 0.2133 | 0.0126 | |
| GSE53622 | CENPT | 80152 | 14104 | 0.1402 | 0.1296 | |
| GSE53624 | CENPT | 80152 | 14104 | 0.1177 | 0.2088 | |
| GSE63941 | CENPT | 80152 | 218148_at | 0.7577 | 0.0033 | |
| GSE77861 | CENPT | 80152 | 218148_at | 0.2856 | 0.1273 | |
| GSE97050 | CENPT | 80152 | A_23_P163580 | -0.2223 | 0.6766 | |
| SRP007169 | CENPT | 80152 | RNAseq | -0.3497 | 0.4151 | |
| SRP008496 | CENPT | 80152 | RNAseq | 0.1317 | 0.6719 | |
| SRP064894 | CENPT | 80152 | RNAseq | 0.4016 | 0.0079 | |
| SRP133303 | CENPT | 80152 | RNAseq | 0.1029 | 0.5987 | |
| SRP159526 | CENPT | 80152 | RNAseq | 0.4440 | 0.3540 | |
| SRP193095 | CENPT | 80152 | RNAseq | 0.6145 | 0.0000 | |
| SRP219564 | CENPT | 80152 | RNAseq | -0.0189 | 0.9520 | |
| TCGA | CENPT | 80152 | RNAseq | 0.0198 | 0.7460 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CENPT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPT | 80152 | 9 | 2 | 19 | |
| GSE20123 | CENPT | 80152 | 9 | 2 | 19 | |
| GSE43470 | CENPT | 80152 | 1 | 9 | 33 | |
| GSE46452 | CENPT | 80152 | 38 | 1 | 20 | |
| GSE47630 | CENPT | 80152 | 11 | 8 | 21 | |
| GSE54993 | CENPT | 80152 | 2 | 4 | 64 | |
| GSE54994 | CENPT | 80152 | 8 | 10 | 35 | |
| GSE60625 | CENPT | 80152 | 4 | 0 | 7 | |
| GSE74703 | CENPT | 80152 | 1 | 6 | 29 | |
| GSE74704 | CENPT | 80152 | 5 | 1 | 14 | |
| TCGA | CENPT | 80152 | 28 | 13 | 55 |
Total number of gains: 116; Total number of losses: 56; Total Number of normals: 316.
Somatic mutations of CENPT:
Generating mutation plots.
Highly correlated genes for CENPT:
Showing top 20/442 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPT | MED9 | 0.783122 | 3 | 0 | 3 |
| CENPT | BRAT1 | 0.782464 | 3 | 0 | 3 |
| CENPT | TP53I13 | 0.747209 | 3 | 0 | 3 |
| CENPT | ZNF417 | 0.734512 | 3 | 0 | 3 |
| CENPT | NTPCR | 0.71983 | 3 | 0 | 3 |
| CENPT | LRP5L | 0.718159 | 3 | 0 | 3 |
| CENPT | MVP | 0.712032 | 3 | 0 | 3 |
| CENPT | CMTM4 | 0.709872 | 3 | 0 | 3 |
| CENPT | DNAH14 | 0.709104 | 3 | 0 | 3 |
| CENPT | NUP35 | 0.708577 | 3 | 0 | 3 |
| CENPT | MSTO1 | 0.707588 | 3 | 0 | 3 |
| CENPT | ZNF384 | 0.700176 | 4 | 0 | 4 |
| CENPT | PFN2 | 0.694901 | 3 | 0 | 3 |
| CENPT | B4GALT3 | 0.685092 | 3 | 0 | 3 |
| CENPT | BCORL1 | 0.676662 | 4 | 0 | 4 |
| CENPT | CHD3 | 0.669811 | 4 | 0 | 3 |
| CENPT | TNK1 | 0.668334 | 5 | 0 | 5 |
| CENPT | TCEANC2 | 0.667385 | 3 | 0 | 3 |
| CENPT | NIPSNAP1 | 0.663667 | 3 | 0 | 3 |
| CENPT | EVI5L | 0.661248 | 4 | 0 | 3 |
For details and further investigation, click here
