| Full name: beta-1,4-galactosyltransferase 3 | Alias Symbol: beta4Gal-T3 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 8703 | HGNC ID: HGNC:926 | Ensembl Gene: ENSG00000158850 | OMIM ID: 604014 |
| Drug and gene relationship at DGIdb | |||
Expression of B4GALT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B4GALT3 | 8703 | 210243_s_at | 0.8389 | 0.0412 | |
| GSE20347 | B4GALT3 | 8703 | 210243_s_at | 0.2519 | 0.0594 | |
| GSE23400 | B4GALT3 | 8703 | 210243_s_at | 0.1578 | 0.0052 | |
| GSE26886 | B4GALT3 | 8703 | 210243_s_at | -0.3190 | 0.0266 | |
| GSE29001 | B4GALT3 | 8703 | 210243_s_at | 0.1137 | 0.6125 | |
| GSE38129 | B4GALT3 | 8703 | 210243_s_at | 0.5305 | 0.0000 | |
| GSE45670 | B4GALT3 | 8703 | 210243_s_at | 0.2490 | 0.0213 | |
| GSE53622 | B4GALT3 | 8703 | 42588 | -2.9178 | 0.0000 | |
| GSE53624 | B4GALT3 | 8703 | 42588 | -2.5837 | 0.0000 | |
| GSE63941 | B4GALT3 | 8703 | 210243_s_at | 0.6191 | 0.0608 | |
| GSE77861 | B4GALT3 | 8703 | 210243_s_at | 0.4259 | 0.0103 | |
| GSE97050 | B4GALT3 | 8703 | A_33_P3335999 | 0.5707 | 0.1392 | |
| SRP007169 | B4GALT3 | 8703 | RNAseq | -0.6146 | 0.0474 | |
| SRP008496 | B4GALT3 | 8703 | RNAseq | -0.1928 | 0.4403 | |
| SRP064894 | B4GALT3 | 8703 | RNAseq | 0.3670 | 0.0982 | |
| SRP133303 | B4GALT3 | 8703 | RNAseq | 0.3217 | 0.0991 | |
| SRP159526 | B4GALT3 | 8703 | RNAseq | 0.8930 | 0.0001 | |
| SRP193095 | B4GALT3 | 8703 | RNAseq | 0.2076 | 0.0352 | |
| SRP219564 | B4GALT3 | 8703 | RNAseq | 0.4283 | 0.3027 | |
| TCGA | B4GALT3 | 8703 | RNAseq | 0.0617 | 0.2520 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by B4GALT3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B4GALT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B4GALT3 | 8703 | 10 | 0 | 20 | |
| GSE20123 | B4GALT3 | 8703 | 10 | 0 | 20 | |
| GSE43470 | B4GALT3 | 8703 | 7 | 2 | 34 | |
| GSE46452 | B4GALT3 | 8703 | 2 | 1 | 56 | |
| GSE47630 | B4GALT3 | 8703 | 14 | 0 | 26 | |
| GSE54993 | B4GALT3 | 8703 | 0 | 6 | 64 | |
| GSE54994 | B4GALT3 | 8703 | 16 | 0 | 37 | |
| GSE60625 | B4GALT3 | 8703 | 0 | 0 | 11 | |
| GSE74703 | B4GALT3 | 8703 | 7 | 2 | 27 | |
| GSE74704 | B4GALT3 | 8703 | 4 | 0 | 16 | |
| TCGA | B4GALT3 | 8703 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of B4GALT3:
Generating mutation plots.
Highly correlated genes for B4GALT3:
Showing top 20/217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B4GALT3 | UHRF2 | 0.824539 | 3 | 0 | 3 |
| B4GALT3 | LTA4H | 0.733017 | 3 | 0 | 3 |
| B4GALT3 | TRMT10B | 0.732041 | 3 | 0 | 3 |
| B4GALT3 | NAF1 | 0.720272 | 3 | 0 | 3 |
| B4GALT3 | TMTC4 | 0.718214 | 3 | 0 | 3 |
| B4GALT3 | PRDM15 | 0.71787 | 3 | 0 | 3 |
| B4GALT3 | CD80 | 0.715698 | 3 | 0 | 3 |
| B4GALT3 | ZNF830 | 0.701078 | 3 | 0 | 3 |
| B4GALT3 | NRIP1 | 0.698674 | 3 | 0 | 3 |
| B4GALT3 | ELOVL1 | 0.693036 | 3 | 0 | 3 |
| B4GALT3 | LRRC8B | 0.686056 | 3 | 0 | 3 |
| B4GALT3 | CENPT | 0.685092 | 3 | 0 | 3 |
| B4GALT3 | DOT1L | 0.684046 | 3 | 0 | 3 |
| B4GALT3 | ADAM15 | 0.681476 | 4 | 0 | 3 |
| B4GALT3 | SMAD1 | 0.679797 | 3 | 0 | 3 |
| B4GALT3 | ULK1 | 0.677075 | 3 | 0 | 3 |
| B4GALT3 | CAPN12 | 0.675454 | 4 | 0 | 3 |
| B4GALT3 | TMEM63B | 0.671666 | 4 | 0 | 3 |
| B4GALT3 | NUAK2 | 0.670459 | 3 | 0 | 3 |
| B4GALT3 | E2F5 | 0.665361 | 5 | 0 | 3 |
For details and further investigation, click here
