| Full name: centrosomal protein 68 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 23177 | HGNC ID: HGNC:29076 | Ensembl Gene: ENSG00000011523 | OMIM ID: 616889 |
| Drug and gene relationship at DGIdb | |||
Expression of CEP68:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEP68 | 23177 | 212675_s_at | -0.3684 | 0.5034 | |
| GSE20347 | CEP68 | 23177 | 212677_s_at | 0.5508 | 0.0239 | |
| GSE23400 | CEP68 | 23177 | 212677_s_at | 0.1131 | 0.3511 | |
| GSE26886 | CEP68 | 23177 | 212675_s_at | 1.0574 | 0.0036 | |
| GSE29001 | CEP68 | 23177 | 212677_s_at | 0.2492 | 0.5851 | |
| GSE38129 | CEP68 | 23177 | 212675_s_at | -0.0610 | 0.8064 | |
| GSE45670 | CEP68 | 23177 | 212675_s_at | -0.7378 | 0.0201 | |
| GSE53622 | CEP68 | 23177 | 30568 | -0.2830 | 0.0192 | |
| GSE53624 | CEP68 | 23177 | 129157 | 0.1330 | 0.0721 | |
| GSE63941 | CEP68 | 23177 | 212675_s_at | -0.0143 | 0.9775 | |
| GSE77861 | CEP68 | 23177 | 212675_s_at | 0.6332 | 0.1894 | |
| GSE97050 | CEP68 | 23177 | A_24_P944049 | -0.5809 | 0.1453 | |
| SRP007169 | CEP68 | 23177 | RNAseq | 0.9228 | 0.0298 | |
| SRP008496 | CEP68 | 23177 | RNAseq | 0.9608 | 0.0005 | |
| SRP064894 | CEP68 | 23177 | RNAseq | -0.1287 | 0.5042 | |
| SRP133303 | CEP68 | 23177 | RNAseq | -0.3344 | 0.0174 | |
| SRP159526 | CEP68 | 23177 | RNAseq | 0.4712 | 0.0919 | |
| SRP193095 | CEP68 | 23177 | RNAseq | 0.3506 | 0.0067 | |
| SRP219564 | CEP68 | 23177 | RNAseq | 0.0041 | 0.9906 | |
| TCGA | CEP68 | 23177 | RNAseq | -0.0468 | 0.4797 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CEP68 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEP68:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEP68 | 23177 | 12 | 0 | 18 | |
| GSE20123 | CEP68 | 23177 | 12 | 0 | 18 | |
| GSE43470 | CEP68 | 23177 | 6 | 1 | 36 | |
| GSE46452 | CEP68 | 23177 | 2 | 3 | 54 | |
| GSE47630 | CEP68 | 23177 | 8 | 0 | 32 | |
| GSE54993 | CEP68 | 23177 | 0 | 6 | 64 | |
| GSE54994 | CEP68 | 23177 | 12 | 0 | 41 | |
| GSE60625 | CEP68 | 23177 | 0 | 3 | 8 | |
| GSE74703 | CEP68 | 23177 | 6 | 1 | 29 | |
| GSE74704 | CEP68 | 23177 | 10 | 0 | 10 | |
| TCGA | CEP68 | 23177 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 16; Total Number of normals: 368.
Somatic mutations of CEP68:
Generating mutation plots.
Highly correlated genes for CEP68:
Showing top 20/737 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEP68 | RP9 | 0.81392 | 3 | 0 | 3 |
| CEP68 | KLHL7 | 0.774079 | 3 | 0 | 3 |
| CEP68 | CYP4V2 | 0.762519 | 3 | 0 | 3 |
| CEP68 | CWF19L2 | 0.756646 | 3 | 0 | 3 |
| CEP68 | ZBTB26 | 0.728177 | 4 | 0 | 3 |
| CEP68 | HERC2 | 0.727592 | 3 | 0 | 3 |
| CEP68 | TET1 | 0.712939 | 3 | 0 | 3 |
| CEP68 | IFNGR1 | 0.709739 | 3 | 0 | 3 |
| CEP68 | PAK1 | 0.706034 | 4 | 0 | 3 |
| CEP68 | XPC | 0.703863 | 3 | 0 | 3 |
| CEP68 | EID3 | 0.700578 | 4 | 0 | 3 |
| CEP68 | LONRF2 | 0.699275 | 3 | 0 | 3 |
| CEP68 | MEPCE | 0.698822 | 4 | 0 | 3 |
| CEP68 | FILIP1 | 0.698088 | 3 | 0 | 3 |
| CEP68 | IPO7 | 0.694928 | 3 | 0 | 3 |
| CEP68 | SLC22A5 | 0.694431 | 3 | 0 | 3 |
| CEP68 | ZFX | 0.690864 | 3 | 0 | 3 |
| CEP68 | TSC22D3 | 0.686494 | 4 | 0 | 3 |
| CEP68 | GOPC | 0.684247 | 3 | 0 | 3 |
| CEP68 | NOA1 | 0.681444 | 3 | 0 | 3 |
For details and further investigation, click here
