| Full name: interleukin 26 | Alias Symbol: AK155|IL-26 | ||
| Type: protein-coding gene | Cytoband: 12q15 | ||
| Entrez ID: 55801 | HGNC ID: HGNC:17119 | Ensembl Gene: ENSG00000111536 | OMIM ID: 605679 |
| Drug and gene relationship at DGIdb | |||
Expression of IL26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL26 | 55801 | 221111_at | -0.1943 | 0.5217 | |
| GSE20347 | IL26 | 55801 | 221111_at | -0.0376 | 0.4570 | |
| GSE23400 | IL26 | 55801 | 221111_at | -0.0161 | 0.2738 | |
| GSE26886 | IL26 | 55801 | 221111_at | -0.1852 | 0.4250 | |
| GSE29001 | IL26 | 55801 | 221111_at | -0.0710 | 0.5242 | |
| GSE38129 | IL26 | 55801 | 221111_at | -0.0137 | 0.7769 | |
| GSE45670 | IL26 | 55801 | 221111_at | 0.1255 | 0.3375 | |
| GSE53622 | IL26 | 55801 | 15140 | -0.0217 | 0.7015 | |
| GSE53624 | IL26 | 55801 | 15140 | 0.0145 | 0.8575 | |
| GSE63941 | IL26 | 55801 | 221111_at | 0.0872 | 0.3985 | |
| GSE77861 | IL26 | 55801 | 221111_at | -0.0623 | 0.5809 | |
| GSE97050 | IL26 | 55801 | A_23_P128503 | 0.0665 | 0.7260 | |
| TCGA | IL26 | 55801 | RNAseq | 2.9168 | 0.0043 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IL26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL26 | 55801 | 6 | 0 | 24 | |
| GSE20123 | IL26 | 55801 | 6 | 0 | 24 | |
| GSE43470 | IL26 | 55801 | 5 | 0 | 38 | |
| GSE46452 | IL26 | 55801 | 13 | 0 | 46 | |
| GSE47630 | IL26 | 55801 | 10 | 1 | 29 | |
| GSE54993 | IL26 | 55801 | 0 | 8 | 62 | |
| GSE54994 | IL26 | 55801 | 7 | 1 | 45 | |
| GSE60625 | IL26 | 55801 | 0 | 0 | 11 | |
| GSE74703 | IL26 | 55801 | 5 | 0 | 31 | |
| GSE74704 | IL26 | 55801 | 5 | 0 | 15 | |
| TCGA | IL26 | 55801 | 24 | 9 | 63 |
Total number of gains: 81; Total number of losses: 19; Total Number of normals: 388.
Somatic mutations of IL26:
Generating mutation plots.
Highly correlated genes for IL26:
Showing top 20/88 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL26 | NLRP6 | 0.799344 | 3 | 0 | 3 |
| IL26 | BHLHA9 | 0.737979 | 3 | 0 | 3 |
| IL26 | PRSS54 | 0.731379 | 3 | 0 | 3 |
| IL26 | BCL2L15 | 0.70728 | 4 | 0 | 3 |
| IL26 | PCDH1 | 0.706564 | 3 | 0 | 3 |
| IL26 | PKD2L1 | 0.705873 | 3 | 0 | 3 |
| IL26 | MAGEE2 | 0.704999 | 3 | 0 | 3 |
| IL26 | C9orf106 | 0.702159 | 3 | 0 | 3 |
| IL26 | KCNT1 | 0.697523 | 3 | 0 | 3 |
| IL26 | TESC | 0.696449 | 3 | 0 | 3 |
| IL26 | GBX2 | 0.685994 | 3 | 0 | 3 |
| IL26 | CHDH | 0.672548 | 3 | 0 | 3 |
| IL26 | CABP7 | 0.672379 | 3 | 0 | 3 |
| IL26 | LIM2 | 0.671823 | 3 | 0 | 3 |
| IL26 | PNPLA5 | 0.669946 | 4 | 0 | 4 |
| IL26 | STAC3 | 0.667151 | 4 | 0 | 3 |
| IL26 | IZUMO2 | 0.661776 | 3 | 0 | 3 |
| IL26 | CTSE | 0.649952 | 4 | 0 | 3 |
| IL26 | CHRNA4 | 0.648484 | 3 | 0 | 3 |
| IL26 | ATG4D | 0.641744 | 3 | 0 | 3 |
For details and further investigation, click here
