| Full name: calcium and integrin binding family member 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 130106 | HGNC ID: HGNC:33703 | Ensembl Gene: ENSG00000157884 | OMIM ID: 610646 |
| Drug and gene relationship at DGIdb | |||
Expression of CIB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CIB4 | 130106 | 236378_at | -0.1260 | 0.6099 | |
| GSE26886 | CIB4 | 130106 | 236378_at | 0.0308 | 0.8628 | |
| GSE45670 | CIB4 | 130106 | 236378_at | 0.1224 | 0.1261 | |
| GSE53622 | CIB4 | 130106 | 52142 | -0.5946 | 0.0000 | |
| GSE53624 | CIB4 | 130106 | 52142 | -0.8168 | 0.0000 | |
| GSE63941 | CIB4 | 130106 | 236378_at | 0.2440 | 0.3271 | |
| GSE77861 | CIB4 | 130106 | 236378_at | -0.0525 | 0.5853 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CIB4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CIB4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CIB4 | 130106 | 11 | 2 | 17 | |
| GSE20123 | CIB4 | 130106 | 11 | 2 | 17 | |
| GSE43470 | CIB4 | 130106 | 3 | 1 | 39 | |
| GSE46452 | CIB4 | 130106 | 3 | 4 | 52 | |
| GSE47630 | CIB4 | 130106 | 8 | 0 | 32 | |
| GSE54993 | CIB4 | 130106 | 0 | 6 | 64 | |
| GSE54994 | CIB4 | 130106 | 10 | 0 | 43 | |
| GSE60625 | CIB4 | 130106 | 0 | 3 | 8 | |
| GSE74703 | CIB4 | 130106 | 3 | 0 | 33 | |
| GSE74704 | CIB4 | 130106 | 9 | 1 | 10 | |
| TCGA | CIB4 | 130106 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of CIB4:
Generating mutation plots.
Highly correlated genes for CIB4:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CIB4 | PLK5 | 0.689751 | 3 | 0 | 3 |
| CIB4 | CAMK2B | 0.662532 | 3 | 0 | 3 |
| CIB4 | C22orf23 | 0.650455 | 3 | 0 | 3 |
| CIB4 | PCGEM1 | 0.631591 | 3 | 0 | 3 |
| CIB4 | LUZP4 | 0.630036 | 4 | 0 | 3 |
| CIB4 | WT1-AS | 0.62444 | 4 | 0 | 3 |
| CIB4 | CRLF2 | 0.624432 | 3 | 0 | 3 |
| CIB4 | MEP1B | 0.619284 | 3 | 0 | 3 |
| CIB4 | CA1 | 0.613491 | 4 | 0 | 4 |
| CIB4 | ADCYAP1R1 | 0.594754 | 3 | 0 | 3 |
| CIB4 | PSPN | 0.594453 | 3 | 0 | 3 |
| CIB4 | ADIG | 0.587695 | 4 | 0 | 3 |
| CIB4 | ASB16 | 0.585422 | 3 | 0 | 3 |
| CIB4 | MAG | 0.585117 | 3 | 0 | 3 |
| CIB4 | TVP23C | 0.583959 | 4 | 0 | 3 |
| CIB4 | SYCE1 | 0.583869 | 4 | 0 | 3 |
| CIB4 | OR4D2 | 0.583628 | 4 | 0 | 3 |
| CIB4 | KIF25 | 0.582978 | 3 | 0 | 3 |
| CIB4 | MAGI1-IT1 | 0.581559 | 3 | 0 | 3 |
| CIB4 | CCDC105 | 0.579191 | 3 | 0 | 3 |
For details and further investigation, click here
