| Full name: superoxide dismutase 3 | Alias Symbol: EC-SOD | ||
| Type: protein-coding gene | Cytoband: 4p15.2 | ||
| Entrez ID: 6649 | HGNC ID: HGNC:11181 | Ensembl Gene: ENSG00000109610 | OMIM ID: 185490 |
| Drug and gene relationship at DGIdb | |||
Expression of SOD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SOD3 | 6649 | 205236_x_at | -0.9470 | 0.3444 | |
| GSE20347 | SOD3 | 6649 | 205236_x_at | -0.0388 | 0.8201 | |
| GSE23400 | SOD3 | 6649 | 205236_x_at | -0.1580 | 0.2854 | |
| GSE26886 | SOD3 | 6649 | 205236_x_at | 0.6449 | 0.0052 | |
| GSE29001 | SOD3 | 6649 | 205236_x_at | -0.1956 | 0.4260 | |
| GSE38129 | SOD3 | 6649 | 205236_x_at | -0.4175 | 0.0638 | |
| GSE45670 | SOD3 | 6649 | 205236_x_at | -0.8142 | 0.0000 | |
| GSE53622 | SOD3 | 6649 | 101384 | -0.7151 | 0.0000 | |
| GSE53624 | SOD3 | 6649 | 101384 | -0.2813 | 0.0000 | |
| GSE63941 | SOD3 | 6649 | 205236_x_at | -0.9029 | 0.0591 | |
| GSE77861 | SOD3 | 6649 | 205236_x_at | 0.0169 | 0.9399 | |
| GSE97050 | SOD3 | 6649 | A_23_P254741 | -0.6666 | 0.1163 | |
| SRP007169 | SOD3 | 6649 | RNAseq | 2.1791 | 0.0011 | |
| SRP064894 | SOD3 | 6649 | RNAseq | -0.8097 | 0.0519 | |
| SRP133303 | SOD3 | 6649 | RNAseq | -1.9738 | 0.0000 | |
| SRP219564 | SOD3 | 6649 | RNAseq | -0.1091 | 0.9286 | |
| TCGA | SOD3 | 6649 | RNAseq | -0.4991 | 0.0018 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SOD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SOD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SOD3 | 6649 | 0 | 18 | 12 | |
| GSE20123 | SOD3 | 6649 | 0 | 16 | 14 | |
| GSE43470 | SOD3 | 6649 | 0 | 15 | 28 | |
| GSE46452 | SOD3 | 6649 | 1 | 36 | 22 | |
| GSE47630 | SOD3 | 6649 | 1 | 19 | 20 | |
| GSE54993 | SOD3 | 6649 | 10 | 0 | 60 | |
| GSE54994 | SOD3 | 6649 | 5 | 11 | 37 | |
| GSE60625 | SOD3 | 6649 | 0 | 0 | 11 | |
| GSE74703 | SOD3 | 6649 | 0 | 13 | 23 | |
| GSE74704 | SOD3 | 6649 | 0 | 10 | 10 | |
| TCGA | SOD3 | 6649 | 11 | 47 | 38 |
Total number of gains: 28; Total number of losses: 185; Total Number of normals: 275.
Somatic mutations of SOD3:
Generating mutation plots.
Highly correlated genes for SOD3:
Showing top 20/1005 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SOD3 | MIR100HG | 0.764201 | 4 | 0 | 4 |
| SOD3 | PCDH9 | 0.75461 | 8 | 0 | 8 |
| SOD3 | DCHS1 | 0.753382 | 7 | 0 | 7 |
| SOD3 | KIF7 | 0.749363 | 3 | 0 | 3 |
| SOD3 | A2M-AS1 | 0.740215 | 3 | 0 | 3 |
| SOD3 | SMTN | 0.737571 | 8 | 0 | 7 |
| SOD3 | SLIT2 | 0.73294 | 8 | 0 | 7 |
| SOD3 | CDH19 | 0.726456 | 8 | 0 | 7 |
| SOD3 | FIBIN | 0.726369 | 4 | 0 | 4 |
| SOD3 | HSPB7 | 0.721513 | 12 | 0 | 11 |
| SOD3 | TACC1 | 0.72049 | 8 | 0 | 7 |
| SOD3 | SEMA3G | 0.719255 | 9 | 0 | 9 |
| SOD3 | ZNF423 | 0.716312 | 7 | 0 | 6 |
| SOD3 | C1QTNF7 | 0.714483 | 5 | 0 | 5 |
| SOD3 | PIPOX | 0.713341 | 3 | 0 | 3 |
| SOD3 | LIMS2 | 0.710889 | 11 | 0 | 9 |
| SOD3 | GIPC3 | 0.708181 | 3 | 0 | 3 |
| SOD3 | PPP1R12B | 0.706633 | 10 | 0 | 8 |
| SOD3 | CBX7 | 0.705331 | 8 | 0 | 7 |
| SOD3 | PLA2G5 | 0.705114 | 9 | 0 | 8 |
For details and further investigation, click here
