| Full name: interleukin 17F | Alias Symbol: IL-17F|ML-1|ML1 | ||
| Type: protein-coding gene | Cytoband: 6p12.2 | ||
| Entrez ID: 112744 | HGNC ID: HGNC:16404 | Ensembl Gene: ENSG00000112116 | OMIM ID: 606496 |
| Drug and gene relationship at DGIdb | |||
IL17F involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05321 | Inflammatory bowel disease (IBD) |
Expression of IL17F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL17F | 112744 | 234408_at | 0.1828 | 0.6266 | |
| GSE26886 | IL17F | 112744 | 234408_at | 0.3233 | 0.0297 | |
| GSE45670 | IL17F | 112744 | 234408_at | 0.1326 | 0.0760 | |
| GSE53622 | IL17F | 112744 | 96705 | -0.0068 | 0.9626 | |
| GSE53624 | IL17F | 112744 | 96705 | 0.2609 | 0.0049 | |
| GSE63941 | IL17F | 112744 | 234408_at | 0.1450 | 0.3772 | |
| GSE77861 | IL17F | 112744 | 234408_at | 0.0550 | 0.7871 | |
| TCGA | IL17F | 112744 | RNAseq | 2.4036 | 0.0816 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IL17F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL17F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL17F | 112744 | 7 | 2 | 21 | |
| GSE20123 | IL17F | 112744 | 8 | 2 | 20 | |
| GSE43470 | IL17F | 112744 | 5 | 0 | 38 | |
| GSE46452 | IL17F | 112744 | 3 | 10 | 46 | |
| GSE47630 | IL17F | 112744 | 7 | 5 | 28 | |
| GSE54993 | IL17F | 112744 | 3 | 1 | 66 | |
| GSE54994 | IL17F | 112744 | 8 | 4 | 41 | |
| GSE60625 | IL17F | 112744 | 0 | 3 | 8 | |
| GSE74703 | IL17F | 112744 | 5 | 0 | 31 | |
| GSE74704 | IL17F | 112744 | 4 | 1 | 15 | |
| TCGA | IL17F | 112744 | 22 | 13 | 61 |
Total number of gains: 72; Total number of losses: 41; Total Number of normals: 375.
Somatic mutations of IL17F:
Generating mutation plots.
Highly correlated genes for IL17F:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL17F | AATK | 0.743128 | 3 | 0 | 3 |
| IL17F | CLCF1 | 0.742634 | 3 | 0 | 3 |
| IL17F | CDH15 | 0.72594 | 3 | 0 | 3 |
| IL17F | KCNC4 | 0.723634 | 3 | 0 | 3 |
| IL17F | MEIS3 | 0.708063 | 3 | 0 | 3 |
| IL17F | TM6SF2 | 0.696379 | 3 | 0 | 3 |
| IL17F | HOXB5 | 0.689948 | 3 | 0 | 3 |
| IL17F | NYX | 0.689075 | 3 | 0 | 3 |
| IL17F | DNAH11 | 0.68112 | 3 | 0 | 3 |
| IL17F | NKAIN4 | 0.680914 | 3 | 0 | 3 |
| IL17F | WNT7B | 0.671295 | 3 | 0 | 3 |
| IL17F | TCAP | 0.669556 | 3 | 0 | 3 |
| IL17F | TTC9B | 0.668833 | 3 | 0 | 3 |
| IL17F | EXTL1 | 0.659388 | 3 | 0 | 3 |
| IL17F | SPEF1 | 0.658783 | 3 | 0 | 3 |
| IL17F | NSMF | 0.658358 | 3 | 0 | 3 |
| IL17F | FURIN | 0.658005 | 3 | 0 | 3 |
| IL17F | SLIT1 | 0.653694 | 3 | 0 | 3 |
| IL17F | MATN4 | 0.650264 | 3 | 0 | 3 |
| IL17F | CTRB2 | 0.648111 | 3 | 0 | 3 |
For details and further investigation, click here
