| Full name: achaete-scute family bHLH transcription factor 5 | Alias Symbol: bHLHa47 | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 647219 | HGNC ID: HGNC:33169 | Ensembl Gene: ENSG00000232237 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASCL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASCL5 | 647219 | 231712_at | 0.0213 | 0.9430 | |
| GSE26886 | ASCL5 | 647219 | 231712_at | 0.5193 | 0.0074 | |
| GSE45670 | ASCL5 | 647219 | 231712_at | 0.0484 | 0.6806 | |
| GSE53622 | ASCL5 | 647219 | 94726 | 0.2984 | 0.0048 | |
| GSE53624 | ASCL5 | 647219 | 94726 | 0.3845 | 0.0005 | |
| GSE63941 | ASCL5 | 647219 | 231712_at | 0.2695 | 0.1446 | |
| GSE77861 | ASCL5 | 647219 | 231712_at | 0.0339 | 0.6960 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ASCL5 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ASCL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASCL5 | 647219 | 11 | 0 | 19 | |
| GSE20123 | ASCL5 | 647219 | 11 | 0 | 19 | |
| GSE43470 | ASCL5 | 647219 | 6 | 0 | 37 | |
| GSE46452 | ASCL5 | 647219 | 3 | 1 | 55 | |
| GSE47630 | ASCL5 | 647219 | 14 | 0 | 26 | |
| GSE54993 | ASCL5 | 647219 | 0 | 6 | 64 | |
| GSE54994 | ASCL5 | 647219 | 15 | 0 | 38 | |
| GSE60625 | ASCL5 | 647219 | 0 | 0 | 11 | |
| GSE74703 | ASCL5 | 647219 | 6 | 0 | 30 | |
| GSE74704 | ASCL5 | 647219 | 5 | 0 | 15 | |
| TCGA | ASCL5 | 647219 | 43 | 4 | 49 |
Total number of gains: 114; Total number of losses: 11; Total Number of normals: 363.
Somatic mutations of ASCL5:
Generating mutation plots.
Highly correlated genes for ASCL5:
Showing top 20/100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASCL5 | AGXT | 0.690666 | 3 | 0 | 3 |
| ASCL5 | SIM1 | 0.683963 | 3 | 0 | 3 |
| ASCL5 | HHATL | 0.683667 | 3 | 0 | 3 |
| ASCL5 | MIOX | 0.665474 | 3 | 0 | 3 |
| ASCL5 | VWA5B1 | 0.660074 | 4 | 0 | 3 |
| ASCL5 | PPP5C | 0.657025 | 3 | 0 | 3 |
| ASCL5 | CLCF1 | 0.654624 | 3 | 0 | 3 |
| ASCL5 | KHDC3L | 0.64286 | 3 | 0 | 3 |
| ASCL5 | KLHL31 | 0.637896 | 3 | 0 | 3 |
| ASCL5 | SLC22A6 | 0.634135 | 4 | 0 | 3 |
| ASCL5 | GNAT1 | 0.632837 | 4 | 0 | 4 |
| ASCL5 | PM20D1 | 0.629819 | 3 | 0 | 3 |
| ASCL5 | MARK4 | 0.629073 | 3 | 0 | 3 |
| ASCL5 | KLK1 | 0.627487 | 3 | 0 | 3 |
| ASCL5 | STAC3 | 0.618254 | 3 | 0 | 3 |
| ASCL5 | SLC18A3 | 0.618081 | 4 | 0 | 3 |
| ASCL5 | ZNF446 | 0.615737 | 3 | 0 | 3 |
| ASCL5 | MAPK8IP2 | 0.613623 | 3 | 0 | 3 |
| ASCL5 | LINC00544 | 0.613349 | 3 | 0 | 3 |
| ASCL5 | C1orf127 | 0.611178 | 3 | 0 | 3 |
For details and further investigation, click here
