| Full name: chromosome 12 open reading frame 40 | Alias Symbol: FLJ40126 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 283461 | HGNC ID: HGNC:26846 | Ensembl Gene: ENSG00000180116 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf40 | 283461 | 1553424_at | -0.0190 | 0.9486 | |
| GSE26886 | C12orf40 | 283461 | 1553424_at | 0.1874 | 0.0883 | |
| GSE45670 | C12orf40 | 283461 | 1553424_at | -0.0329 | 0.7553 | |
| GSE53622 | C12orf40 | 283461 | 47455 | -1.2407 | 0.0000 | |
| GSE53624 | C12orf40 | 283461 | 47455 | -1.0287 | 0.0000 | |
| GSE63941 | C12orf40 | 283461 | 1553424_at | 0.2252 | 0.0596 | |
| GSE77861 | C12orf40 | 283461 | 1553424_at | -0.0424 | 0.6181 | |
| SRP133303 | C12orf40 | 283461 | RNAseq | 0.1778 | 0.3827 | |
| SRP193095 | C12orf40 | 283461 | RNAseq | 0.4153 | 0.0276 | |
| TCGA | C12orf40 | 283461 | RNAseq | 0.3259 | 0.8420 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by C12orf40 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf40 | 283461 | 6 | 1 | 23 | |
| GSE20123 | C12orf40 | 283461 | 6 | 1 | 23 | |
| GSE43470 | C12orf40 | 283461 | 5 | 3 | 35 | |
| GSE46452 | C12orf40 | 283461 | 8 | 1 | 50 | |
| GSE47630 | C12orf40 | 283461 | 11 | 2 | 27 | |
| GSE54993 | C12orf40 | 283461 | 1 | 8 | 61 | |
| GSE54994 | C12orf40 | 283461 | 7 | 1 | 45 | |
| GSE60625 | C12orf40 | 283461 | 0 | 0 | 11 | |
| GSE74703 | C12orf40 | 283461 | 4 | 2 | 30 | |
| GSE74704 | C12orf40 | 283461 | 3 | 1 | 16 | |
| TCGA | C12orf40 | 283461 | 18 | 13 | 65 |
Total number of gains: 69; Total number of losses: 33; Total Number of normals: 386.
Somatic mutations of C12orf40:
Generating mutation plots.
Highly correlated genes for C12orf40:
Showing top 20/128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf40 | CLDN19 | 0.751736 | 3 | 0 | 3 |
| C12orf40 | STAR | 0.699279 | 3 | 0 | 3 |
| C12orf40 | NXNL1 | 0.684407 | 3 | 0 | 3 |
| C12orf40 | C4orf45 | 0.673417 | 3 | 0 | 3 |
| C12orf40 | LPIN3 | 0.659421 | 3 | 0 | 3 |
| C12orf40 | ARHGDIG | 0.639282 | 3 | 0 | 3 |
| C12orf40 | MAP1LC3B2 | 0.634486 | 3 | 0 | 3 |
| C12orf40 | SLC6A13 | 0.632381 | 3 | 0 | 3 |
| C12orf40 | CYP17A1 | 0.630779 | 3 | 0 | 3 |
| C12orf40 | XRRA1 | 0.629899 | 3 | 0 | 3 |
| C12orf40 | SOX10 | 0.62737 | 3 | 0 | 3 |
| C12orf40 | SRD5A2 | 0.624121 | 3 | 0 | 3 |
| C12orf40 | BEND4 | 0.622028 | 4 | 0 | 3 |
| C12orf40 | FAM186B | 0.620812 | 3 | 0 | 3 |
| C12orf40 | CLCF1 | 0.619101 | 3 | 0 | 3 |
| C12orf40 | FOXN4 | 0.618761 | 3 | 0 | 3 |
| C12orf40 | BTNL3 | 0.618167 | 4 | 0 | 4 |
| C12orf40 | CNTD2 | 0.612536 | 3 | 0 | 3 |
| C12orf40 | ZSCAN10 | 0.610276 | 4 | 0 | 4 |
| C12orf40 | C20orf141 | 0.608551 | 4 | 0 | 4 |
For details and further investigation, click here
