| Full name: chloride intracellular channel 1 | Alias Symbol: NCC27|p64CLCP|G6|CLCNL1 | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 1192 | HGNC ID: HGNC:2062 | Ensembl Gene: ENSG00000213719 | OMIM ID: 602872 |
| Drug and gene relationship at DGIdb | |||
Expression of CLIC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLIC1 | 1192 | 208659_at | 0.1843 | 0.7058 | |
| GSE20347 | CLIC1 | 1192 | 208659_at | -0.2216 | 0.0956 | |
| GSE23400 | CLIC1 | 1192 | 208659_at | 0.0770 | 0.2981 | |
| GSE26886 | CLIC1 | 1192 | 208659_at | -0.0279 | 0.9053 | |
| GSE29001 | CLIC1 | 1192 | 208659_at | -0.4578 | 0.3003 | |
| GSE38129 | CLIC1 | 1192 | 208659_at | 0.1109 | 0.3688 | |
| GSE45670 | CLIC1 | 1192 | 208659_at | 0.0998 | 0.4475 | |
| GSE53622 | CLIC1 | 1192 | 163354 | -0.1548 | 0.0433 | |
| GSE53624 | CLIC1 | 1192 | 163354 | 0.0164 | 0.8106 | |
| GSE63941 | CLIC1 | 1192 | 208659_at | 0.1848 | 0.6620 | |
| GSE77861 | CLIC1 | 1192 | 208659_at | 0.0102 | 0.9763 | |
| GSE97050 | CLIC1 | 1192 | A_23_P30884 | 0.4171 | 0.3001 | |
| SRP007169 | CLIC1 | 1192 | RNAseq | -0.1243 | 0.7313 | |
| SRP008496 | CLIC1 | 1192 | RNAseq | -0.1909 | 0.3041 | |
| SRP064894 | CLIC1 | 1192 | RNAseq | 0.2237 | 0.3871 | |
| SRP133303 | CLIC1 | 1192 | RNAseq | 0.0709 | 0.5888 | |
| SRP159526 | CLIC1 | 1192 | RNAseq | -0.3417 | 0.2692 | |
| SRP193095 | CLIC1 | 1192 | RNAseq | -0.3047 | 0.0357 | |
| SRP219564 | CLIC1 | 1192 | RNAseq | -0.0722 | 0.8599 | |
| TCGA | CLIC1 | 1192 | RNAseq | 0.1105 | 0.0175 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLIC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLIC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLIC1 | 1192 | 5 | 1 | 24 | |
| GSE20123 | CLIC1 | 1192 | 5 | 1 | 24 | |
| GSE43470 | CLIC1 | 1192 | 5 | 1 | 37 | |
| GSE46452 | CLIC1 | 1192 | 1 | 10 | 48 | |
| GSE47630 | CLIC1 | 1192 | 7 | 4 | 29 | |
| GSE54993 | CLIC1 | 1192 | 2 | 1 | 67 | |
| GSE54994 | CLIC1 | 1192 | 11 | 4 | 38 | |
| GSE60625 | CLIC1 | 1192 | 0 | 1 | 10 | |
| GSE74703 | CLIC1 | 1192 | 5 | 0 | 31 | |
| GSE74704 | CLIC1 | 1192 | 2 | 0 | 18 | |
| TCGA | CLIC1 | 1192 | 16 | 16 | 64 |
Total number of gains: 59; Total number of losses: 39; Total Number of normals: 390.
Somatic mutations of CLIC1:
Generating mutation plots.
Highly correlated genes for CLIC1:
Showing top 20/462 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLIC1 | ALDH18A1 | 0.748326 | 3 | 0 | 3 |
| CLIC1 | NAA50 | 0.726613 | 3 | 0 | 3 |
| CLIC1 | REST | 0.721831 | 3 | 0 | 3 |
| CLIC1 | TBL2 | 0.72152 | 3 | 0 | 3 |
| CLIC1 | POLR2G | 0.70534 | 3 | 0 | 3 |
| CLIC1 | ZBTB9 | 0.700736 | 4 | 0 | 3 |
| CLIC1 | RNASET2 | 0.700139 | 3 | 0 | 3 |
| CLIC1 | C12orf10 | 0.698493 | 3 | 0 | 3 |
| CLIC1 | UBE2L3 | 0.697471 | 6 | 0 | 6 |
| CLIC1 | LRP11 | 0.69265 | 3 | 0 | 3 |
| CLIC1 | GLIS3 | 0.690411 | 3 | 0 | 3 |
| CLIC1 | WIPF2 | 0.68354 | 3 | 0 | 3 |
| CLIC1 | EIF6 | 0.6829 | 9 | 0 | 8 |
| CLIC1 | EAPP | 0.678338 | 3 | 0 | 3 |
| CLIC1 | GTF2A1 | 0.671815 | 4 | 0 | 3 |
| CLIC1 | GSTZ1 | 0.671183 | 5 | 0 | 4 |
| CLIC1 | ZNF184 | 0.667815 | 5 | 0 | 4 |
| CLIC1 | RRP36 | 0.66712 | 7 | 0 | 6 |
| CLIC1 | SLC22A23 | 0.666252 | 3 | 0 | 3 |
| CLIC1 | KIF3B | 0.662998 | 3 | 0 | 3 |
For details and further investigation, click here
