| Full name: kinesin family member 3B | Alias Symbol: KIAA0359|FLA8|KLP-11 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 9371 | HGNC ID: HGNC:6320 | Ensembl Gene: ENSG00000101350 | OMIM ID: 603754 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KIF3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF3B | 9371 | 225205_at | 1.0164 | 0.0632 | |
| GSE20347 | KIF3B | 9371 | 203943_at | 0.8563 | 0.0000 | |
| GSE23400 | KIF3B | 9371 | 203943_at | 0.5354 | 0.0000 | |
| GSE26886 | KIF3B | 9371 | 225205_at | 1.1058 | 0.0000 | |
| GSE29001 | KIF3B | 9371 | 203943_at | 0.8807 | 0.0009 | |
| GSE38129 | KIF3B | 9371 | 203943_at | 0.5987 | 0.0000 | |
| GSE45670 | KIF3B | 9371 | 225205_at | 0.4993 | 0.0011 | |
| GSE53622 | KIF3B | 9371 | 87211 | 0.8889 | 0.0000 | |
| GSE53624 | KIF3B | 9371 | 87211 | 1.0333 | 0.0000 | |
| GSE63941 | KIF3B | 9371 | 225205_at | -0.8594 | 0.0260 | |
| GSE77861 | KIF3B | 9371 | 225205_at | 0.6729 | 0.0168 | |
| GSE97050 | KIF3B | 9371 | A_24_P941824 | 0.6543 | 0.1905 | |
| SRP007169 | KIF3B | 9371 | RNAseq | 1.4342 | 0.0003 | |
| SRP008496 | KIF3B | 9371 | RNAseq | 1.3831 | 0.0000 | |
| SRP064894 | KIF3B | 9371 | RNAseq | 0.9696 | 0.0000 | |
| SRP133303 | KIF3B | 9371 | RNAseq | 0.7342 | 0.0000 | |
| SRP159526 | KIF3B | 9371 | RNAseq | 0.8663 | 0.0010 | |
| SRP193095 | KIF3B | 9371 | RNAseq | 0.5893 | 0.0008 | |
| SRP219564 | KIF3B | 9371 | RNAseq | 0.7477 | 0.0422 | |
| TCGA | KIF3B | 9371 | RNAseq | -0.0657 | 0.1449 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by KIF3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF3B | 9371 | 15 | 0 | 15 | |
| GSE20123 | KIF3B | 9371 | 15 | 0 | 15 | |
| GSE43470 | KIF3B | 9371 | 12 | 0 | 31 | |
| GSE46452 | KIF3B | 9371 | 29 | 0 | 30 | |
| GSE47630 | KIF3B | 9371 | 24 | 1 | 15 | |
| GSE54993 | KIF3B | 9371 | 0 | 18 | 52 | |
| GSE54994 | KIF3B | 9371 | 26 | 1 | 26 | |
| GSE60625 | KIF3B | 9371 | 0 | 0 | 11 | |
| GSE74703 | KIF3B | 9371 | 11 | 0 | 25 | |
| GSE74704 | KIF3B | 9371 | 10 | 0 | 10 | |
| TCGA | KIF3B | 9371 | 49 | 1 | 46 |
Total number of gains: 191; Total number of losses: 21; Total Number of normals: 276.
Somatic mutations of KIF3B:
Generating mutation plots.
Highly correlated genes for KIF3B:
Showing top 20/1610 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF3B | SNAP47 | 0.772003 | 3 | 0 | 3 |
| KIF3B | ZNF707 | 0.756334 | 3 | 0 | 3 |
| KIF3B | USP42 | 0.75437 | 5 | 0 | 5 |
| KIF3B | SH3RF3 | 0.753345 | 3 | 0 | 3 |
| KIF3B | ALG10B | 0.748474 | 3 | 0 | 3 |
| KIF3B | MMS22L | 0.746095 | 3 | 0 | 3 |
| KIF3B | NF1 | 0.737409 | 3 | 0 | 3 |
| KIF3B | HHAT | 0.733527 | 3 | 0 | 3 |
| KIF3B | YWHAG | 0.732313 | 3 | 0 | 3 |
| KIF3B | KTI12 | 0.732205 | 3 | 0 | 3 |
| KIF3B | MGAT4B | 0.731471 | 3 | 0 | 3 |
| KIF3B | SLC35B3 | 0.7306 | 3 | 0 | 3 |
| KIF3B | UHMK1 | 0.730503 | 6 | 0 | 6 |
| KIF3B | APMAP | 0.726004 | 11 | 0 | 10 |
| KIF3B | KLHL36 | 0.725314 | 4 | 0 | 4 |
| KIF3B | RAB34 | 0.721684 | 3 | 0 | 3 |
| KIF3B | PDRG1 | 0.720237 | 7 | 0 | 6 |
| KIF3B | FADS1 | 0.719971 | 3 | 0 | 3 |
| KIF3B | SLC39A10 | 0.719631 | 6 | 0 | 5 |
| KIF3B | MEX3B | 0.719352 | 4 | 0 | 4 |
For details and further investigation, click here
