| Full name: glutathione S-transferase zeta 1 | Alias Symbol: GSTZ1-1|MAAI|MAI | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 2954 | HGNC ID: HGNC:4643 | Ensembl Gene: ENSG00000100577 | OMIM ID: 603758 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTZ1 | 2954 | 209531_at | -0.7850 | 0.1270 | |
| GSE20347 | GSTZ1 | 2954 | 209531_at | -0.5858 | 0.0037 | |
| GSE23400 | GSTZ1 | 2954 | 209531_at | 0.0570 | 0.5735 | |
| GSE26886 | GSTZ1 | 2954 | 209531_at | -0.2091 | 0.3146 | |
| GSE29001 | GSTZ1 | 2954 | 209531_at | -0.1876 | 0.5178 | |
| GSE38129 | GSTZ1 | 2954 | 209531_at | -0.2712 | 0.1929 | |
| GSE45670 | GSTZ1 | 2954 | 209531_at | 0.0447 | 0.8466 | |
| GSE53622 | GSTZ1 | 2954 | 57976 | -0.2337 | 0.0298 | |
| GSE53624 | GSTZ1 | 2954 | 57976 | -0.1919 | 0.0400 | |
| GSE63941 | GSTZ1 | 2954 | 209531_at | 1.0273 | 0.0480 | |
| GSE77861 | GSTZ1 | 2954 | 209531_at | -0.1593 | 0.6841 | |
| GSE97050 | GSTZ1 | 2954 | A_23_P106204 | 0.1035 | 0.6763 | |
| SRP007169 | GSTZ1 | 2954 | RNAseq | 0.3741 | 0.5617 | |
| SRP064894 | GSTZ1 | 2954 | RNAseq | 0.5517 | 0.0752 | |
| SRP133303 | GSTZ1 | 2954 | RNAseq | -0.1541 | 0.6170 | |
| SRP159526 | GSTZ1 | 2954 | RNAseq | -0.3523 | 0.4542 | |
| SRP193095 | GSTZ1 | 2954 | RNAseq | -0.6661 | 0.0000 | |
| SRP219564 | GSTZ1 | 2954 | RNAseq | 0.1662 | 0.7043 | |
| TCGA | GSTZ1 | 2954 | RNAseq | 0.0187 | 0.8251 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GSTZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTZ1 | 2954 | 8 | 3 | 19 | |
| GSE20123 | GSTZ1 | 2954 | 8 | 3 | 19 | |
| GSE43470 | GSTZ1 | 2954 | 8 | 3 | 32 | |
| GSE46452 | GSTZ1 | 2954 | 16 | 3 | 40 | |
| GSE47630 | GSTZ1 | 2954 | 11 | 8 | 21 | |
| GSE54993 | GSTZ1 | 2954 | 3 | 8 | 59 | |
| GSE54994 | GSTZ1 | 2954 | 19 | 4 | 30 | |
| GSE60625 | GSTZ1 | 2954 | 0 | 2 | 9 | |
| GSE74703 | GSTZ1 | 2954 | 7 | 3 | 26 | |
| GSE74704 | GSTZ1 | 2954 | 3 | 3 | 14 | |
| TCGA | GSTZ1 | 2954 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of GSTZ1:
Generating mutation plots.
Highly correlated genes for GSTZ1:
Showing top 20/485 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTZ1 | CETN2 | 0.735416 | 3 | 0 | 3 |
| GSTZ1 | IMPACT | 0.733809 | 3 | 0 | 3 |
| GSTZ1 | HIPK1 | 0.724006 | 3 | 0 | 3 |
| GSTZ1 | COPS2 | 0.7228 | 3 | 0 | 3 |
| GSTZ1 | C15orf62 | 0.718197 | 3 | 0 | 3 |
| GSTZ1 | COX16 | 0.704404 | 4 | 0 | 4 |
| GSTZ1 | PSMD8 | 0.701715 | 3 | 0 | 3 |
| GSTZ1 | TAF7 | 0.700091 | 3 | 0 | 3 |
| GSTZ1 | ITGA2 | 0.696131 | 3 | 0 | 3 |
| GSTZ1 | PTCD2 | 0.694708 | 3 | 0 | 3 |
| GSTZ1 | FASTKD2 | 0.693212 | 4 | 0 | 4 |
| GSTZ1 | ACSL3 | 0.688734 | 3 | 0 | 3 |
| GSTZ1 | CHURC1 | 0.686388 | 4 | 0 | 4 |
| GSTZ1 | ZBTB25 | 0.685273 | 4 | 0 | 4 |
| GSTZ1 | ZC3H14 | 0.684739 | 3 | 0 | 3 |
| GSTZ1 | VPS41 | 0.67386 | 3 | 0 | 3 |
| GSTZ1 | VPS26A | 0.672696 | 4 | 0 | 3 |
| GSTZ1 | PSMD7 | 0.671911 | 4 | 0 | 3 |
| GSTZ1 | AMD1 | 0.671846 | 4 | 0 | 3 |
| GSTZ1 | CLIC1 | 0.671183 | 5 | 0 | 4 |
For details and further investigation, click here
