| Full name: LDL receptor related protein 11 | Alias Symbol: bA350J20.3|MANSC3 | ||
| Type: protein-coding gene | Cytoband: 6q25.1 | ||
| Entrez ID: 84918 | HGNC ID: HGNC:16936 | Ensembl Gene: ENSG00000120256 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRP11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRP11 | 84918 | 225060_at | 0.2111 | 0.8184 | |
| GSE26886 | LRP11 | 84918 | 225060_at | -0.9998 | 0.0001 | |
| GSE45670 | LRP11 | 84918 | 225060_at | 0.2257 | 0.2334 | |
| GSE53622 | LRP11 | 84918 | 98704 | -0.0694 | 0.5658 | |
| GSE53624 | LRP11 | 84918 | 98704 | -0.2051 | 0.0183 | |
| GSE63941 | LRP11 | 84918 | 225060_at | -0.7902 | 0.2282 | |
| GSE77861 | LRP11 | 84918 | 225060_at | -0.3570 | 0.1226 | |
| GSE97050 | LRP11 | 84918 | A_23_P19657 | 0.5298 | 0.1255 | |
| SRP007169 | LRP11 | 84918 | RNAseq | -0.6488 | 0.1357 | |
| SRP008496 | LRP11 | 84918 | RNAseq | -0.5728 | 0.0525 | |
| SRP064894 | LRP11 | 84918 | RNAseq | -0.0234 | 0.9257 | |
| SRP133303 | LRP11 | 84918 | RNAseq | 0.1309 | 0.4231 | |
| SRP159526 | LRP11 | 84918 | RNAseq | -0.4422 | 0.2280 | |
| SRP193095 | LRP11 | 84918 | RNAseq | -0.3462 | 0.0492 | |
| SRP219564 | LRP11 | 84918 | RNAseq | -0.7480 | 0.1462 | |
| TCGA | LRP11 | 84918 | RNAseq | 0.0848 | 0.1939 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRP11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRP11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRP11 | 84918 | 2 | 4 | 24 | |
| GSE20123 | LRP11 | 84918 | 1 | 3 | 26 | |
| GSE43470 | LRP11 | 84918 | 4 | 0 | 39 | |
| GSE46452 | LRP11 | 84918 | 3 | 10 | 46 | |
| GSE47630 | LRP11 | 84918 | 9 | 4 | 27 | |
| GSE54993 | LRP11 | 84918 | 3 | 2 | 65 | |
| GSE54994 | LRP11 | 84918 | 8 | 8 | 37 | |
| GSE60625 | LRP11 | 84918 | 0 | 1 | 10 | |
| GSE74703 | LRP11 | 84918 | 4 | 0 | 32 | |
| GSE74704 | LRP11 | 84918 | 0 | 1 | 19 | |
| TCGA | LRP11 | 84918 | 11 | 21 | 64 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of LRP11:
Generating mutation plots.
Highly correlated genes for LRP11:
Showing top 20/558 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRP11 | KDM2B | 0.828442 | 3 | 0 | 3 |
| LRP11 | PIGM | 0.77453 | 3 | 0 | 3 |
| LRP11 | SLC35A5 | 0.761035 | 3 | 0 | 3 |
| LRP11 | RBM20 | 0.754998 | 3 | 0 | 3 |
| LRP11 | STK38 | 0.753434 | 3 | 0 | 3 |
| LRP11 | C2orf76 | 0.751604 | 3 | 0 | 3 |
| LRP11 | LATS1 | 0.747986 | 3 | 0 | 3 |
| LRP11 | DDAH1 | 0.746098 | 3 | 0 | 3 |
| LRP11 | PPIP5K2 | 0.738167 | 3 | 0 | 3 |
| LRP11 | PGM1 | 0.73506 | 3 | 0 | 3 |
| LRP11 | SPIN4 | 0.732442 | 4 | 0 | 3 |
| LRP11 | MAP4K5 | 0.726299 | 4 | 0 | 3 |
| LRP11 | SGSH | 0.724262 | 4 | 0 | 4 |
| LRP11 | TRAPPC6B | 0.721579 | 4 | 0 | 3 |
| LRP11 | C2orf16 | 0.721424 | 3 | 0 | 3 |
| LRP11 | ZNF662 | 0.716985 | 3 | 0 | 3 |
| LRP11 | GANC | 0.715847 | 4 | 0 | 4 |
| LRP11 | ZNF485 | 0.712598 | 3 | 0 | 3 |
| LRP11 | PLEKHM2 | 0.710428 | 3 | 0 | 3 |
| LRP11 | ZNF354B | 0.709701 | 3 | 0 | 3 |
For details and further investigation, click here
