| Full name: solute carrier family 22 member 23 | Alias Symbol: FLJ22174 | ||
| Type: protein-coding gene | Cytoband: 6p25.2 | ||
| Entrez ID: 63027 | HGNC ID: HGNC:21106 | Ensembl Gene: ENSG00000137266 | OMIM ID: 611697 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC22A23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC22A23 | 63027 | 223194_s_at | 0.2660 | 0.6941 | |
| GSE26886 | SLC22A23 | 63027 | 223194_s_at | -0.6143 | 0.0273 | |
| GSE45670 | SLC22A23 | 63027 | 223194_s_at | 0.2723 | 0.0614 | |
| GSE53622 | SLC22A23 | 63027 | 75531 | -0.3255 | 0.0078 | |
| GSE53624 | SLC22A23 | 63027 | 75531 | -0.3027 | 0.0000 | |
| GSE63941 | SLC22A23 | 63027 | 223194_s_at | -0.9837 | 0.1111 | |
| GSE77861 | SLC22A23 | 63027 | 223194_s_at | 0.1442 | 0.6738 | |
| GSE97050 | SLC22A23 | 63027 | A_33_P3409154 | 0.2594 | 0.2631 | |
| SRP007169 | SLC22A23 | 63027 | RNAseq | -1.1829 | 0.0001 | |
| SRP008496 | SLC22A23 | 63027 | RNAseq | -0.5982 | 0.0863 | |
| SRP064894 | SLC22A23 | 63027 | RNAseq | -0.0934 | 0.6898 | |
| SRP133303 | SLC22A23 | 63027 | RNAseq | -0.2783 | 0.1937 | |
| SRP159526 | SLC22A23 | 63027 | RNAseq | -0.1782 | 0.6737 | |
| SRP193095 | SLC22A23 | 63027 | RNAseq | -0.4688 | 0.0009 | |
| SRP219564 | SLC22A23 | 63027 | RNAseq | -0.4197 | 0.5018 | |
| TCGA | SLC22A23 | 63027 | RNAseq | -0.0842 | 0.3191 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC22A23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC22A23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC22A23 | 63027 | 4 | 5 | 21 | |
| GSE20123 | SLC22A23 | 63027 | 4 | 5 | 21 | |
| GSE43470 | SLC22A23 | 63027 | 8 | 2 | 33 | |
| GSE46452 | SLC22A23 | 63027 | 1 | 10 | 48 | |
| GSE47630 | SLC22A23 | 63027 | 7 | 8 | 25 | |
| GSE54993 | SLC22A23 | 63027 | 1 | 1 | 68 | |
| GSE54994 | SLC22A23 | 63027 | 10 | 3 | 40 | |
| GSE60625 | SLC22A23 | 63027 | 0 | 1 | 10 | |
| GSE74703 | SLC22A23 | 63027 | 7 | 2 | 27 | |
| GSE74704 | SLC22A23 | 63027 | 2 | 2 | 16 | |
| TCGA | SLC22A23 | 63027 | 17 | 30 | 49 |
Total number of gains: 61; Total number of losses: 69; Total Number of normals: 358.
Somatic mutations of SLC22A23:
Generating mutation plots.
Highly correlated genes for SLC22A23:
Showing top 20/416 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC22A23 | PDCD6 | 0.769269 | 3 | 0 | 3 |
| SLC22A23 | GLTP | 0.751397 | 3 | 0 | 3 |
| SLC22A23 | E2F2 | 0.751029 | 3 | 0 | 3 |
| SLC22A23 | CAPZA1 | 0.749312 | 3 | 0 | 3 |
| SLC22A23 | NHSL1 | 0.73248 | 4 | 0 | 3 |
| SLC22A23 | EIF6 | 0.721455 | 3 | 0 | 3 |
| SLC22A23 | AP2S1 | 0.71578 | 3 | 0 | 3 |
| SLC22A23 | FDXR | 0.705573 | 3 | 0 | 3 |
| SLC22A23 | DDX52 | 0.691004 | 3 | 0 | 3 |
| SLC22A23 | XKRX | 0.685619 | 4 | 0 | 4 |
| SLC22A23 | WIPF2 | 0.685413 | 4 | 0 | 4 |
| SLC22A23 | CKMT1A | 0.683155 | 3 | 0 | 3 |
| SLC22A23 | KCNK7 | 0.682829 | 3 | 0 | 3 |
| SLC22A23 | MOSPD3 | 0.681294 | 3 | 0 | 3 |
| SLC22A23 | SH2D4A | 0.680376 | 4 | 0 | 3 |
| SLC22A23 | ORMDL2 | 0.679093 | 3 | 0 | 3 |
| SLC22A23 | ARF3 | 0.678214 | 3 | 0 | 3 |
| SLC22A23 | IPMK | 0.677205 | 3 | 0 | 3 |
| SLC22A23 | EYA3 | 0.671304 | 3 | 0 | 3 |
| SLC22A23 | CNKSR1 | 0.670476 | 3 | 0 | 3 |
For details and further investigation, click here
