POLR2G

 

Full name: RNA polymerase II subunit G Alias Symbol: hRPB19|hsRPB7|RPB7
Type: protein-coding gene Cytoband: 11q12.3
Entrez ID: 5436 HGNC ID: HGNC:9194 Ensembl Gene: ENSG00000168002 OMIM ID: 602013
Drug and gene relationship at DGIdb

 

Expression of POLR2G:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 POLR2G 5436 202306_at 0.3332 0.4246
GSE20347 POLR2G 5436 202306_at 0.5205 0.0018
GSE23400 POLR2G 5436 202306_at 0.5801 0.0000
GSE26886 POLR2G 5436 202306_at 0.6990 0.0000
GSE29001 POLR2G 5436 202306_at 0.4016 0.1640
GSE38129 POLR2G 5436 202306_at 0.6068 0.0000
GSE45670 POLR2G 5436 202306_at 0.4519 0.0009
GSE53622 POLR2G 5436 26172 0.3607 0.0000
GSE53624 POLR2G 5436 26172 0.8335 0.0000
GSE63941 POLR2G 5436 202306_at 0.4756 0.2202
GSE77861 POLR2G 5436 202306_at 0.4861 0.0065
GSE97050 POLR2G 5436 A_33_P3396522 0.2892 0.2422
SRP007169 POLR2G 5436 RNAseq 0.8815 0.0239
SRP008496 POLR2G 5436 RNAseq 0.7470 0.0028
SRP064894 POLR2G 5436 RNAseq 0.6690 0.0021
SRP133303 POLR2G 5436 RNAseq 0.4667 0.0140
SRP159526 POLR2G 5436 RNAseq 0.3899 0.0093
SRP193095 POLR2G 5436 RNAseq 0.3038 0.0088
SRP219564 POLR2G 5436 RNAseq 0.3765 0.3555
TCGA POLR2G 5436 RNAseq 0.2168 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by POLR2G expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of POLR2G:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 POLR2G 5436 6 5 19
GSE20123 POLR2G 5436 6 5 19
GSE43470 POLR2G 5436 1 6 36
GSE46452 POLR2G 5436 8 4 47
GSE47630 POLR2G 5436 3 7 30
GSE54993 POLR2G 5436 3 0 67
GSE54994 POLR2G 5436 4 5 44
GSE60625 POLR2G 5436 0 3 8
GSE74703 POLR2G 5436 1 3 32
GSE74704 POLR2G 5436 4 3 13
TCGA POLR2G 5436 12 11 73

Total number of gains: 48; Total number of losses: 52; Total Number of normals: 388.  


 

Somatic mutations of POLR2G:

 

Generating mutation plots.

 

Highly correlated genes for POLR2G:

 

Showing top 20/1958 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
POLR2GSLC39A30.788332303
POLR2GEBNA1BP20.783024303
POLR2GZNF7070.78236303
POLR2GFHOD30.769457303
POLR2GZNF2670.758218303
POLR2GHAS30.755976403
POLR2GKDSR0.75557303
POLR2GPDPR0.754611404
POLR2GCRTC20.753302404
POLR2GRPA30.74788911011
POLR2GPHLPP10.747862303
POLR2GHSD17B110.746208303
POLR2GSLC38A50.743559303
POLR2GHIBADH0.74319404
POLR2GBOLA30.740993606
POLR2GSSRP10.74041313012
POLR2GPRELID20.737446303
POLR2GCTBP20.73582404
POLR2GZNF6640.73516303
POLR2GTEAD20.73143303

For details and further investigation, click here