| Full name: solute carrier family 44 member 3 | Alias Symbol: MGC45474|CTL3 | ||
| Type: protein-coding gene | Cytoband: 1p21.3 | ||
| Entrez ID: 126969 | HGNC ID: HGNC:28689 | Ensembl Gene: ENSG00000143036 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
SLC44A3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05231 | Choline metabolism in cancer |
Expression of SLC44A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC44A3 | 126969 | 228221_at | -0.9507 | 0.3760 | |
| GSE26886 | SLC44A3 | 126969 | 228221_at | -2.7859 | 0.0000 | |
| GSE45670 | SLC44A3 | 126969 | 228221_at | -1.1056 | 0.0094 | |
| GSE53622 | SLC44A3 | 126969 | 6839 | -1.4110 | 0.0000 | |
| GSE53624 | SLC44A3 | 126969 | 6839 | -1.9333 | 0.0000 | |
| GSE63941 | SLC44A3 | 126969 | 228221_at | -0.0380 | 0.9767 | |
| GSE77861 | SLC44A3 | 126969 | 228221_at | -1.9752 | 0.0003 | |
| GSE97050 | SLC44A3 | 126969 | A_23_P86195 | -0.4053 | 0.3410 | |
| SRP007169 | SLC44A3 | 126969 | RNAseq | -3.5780 | 0.0000 | |
| SRP064894 | SLC44A3 | 126969 | RNAseq | -1.3830 | 0.0005 | |
| SRP133303 | SLC44A3 | 126969 | RNAseq | -1.9101 | 0.0000 | |
| SRP159526 | SLC44A3 | 126969 | RNAseq | -2.3970 | 0.0000 | |
| SRP193095 | SLC44A3 | 126969 | RNAseq | -1.4531 | 0.0000 | |
| SRP219564 | SLC44A3 | 126969 | RNAseq | -0.9048 | 0.1560 | |
| TCGA | SLC44A3 | 126969 | RNAseq | -0.8865 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by SLC44A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC44A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC44A3 | 126969 | 0 | 8 | 22 | |
| GSE20123 | SLC44A3 | 126969 | 0 | 8 | 22 | |
| GSE43470 | SLC44A3 | 126969 | 2 | 6 | 35 | |
| GSE46452 | SLC44A3 | 126969 | 1 | 1 | 57 | |
| GSE47630 | SLC44A3 | 126969 | 8 | 5 | 27 | |
| GSE54993 | SLC44A3 | 126969 | 0 | 1 | 69 | |
| GSE54994 | SLC44A3 | 126969 | 6 | 3 | 44 | |
| GSE60625 | SLC44A3 | 126969 | 0 | 0 | 11 | |
| GSE74703 | SLC44A3 | 126969 | 1 | 5 | 30 | |
| GSE74704 | SLC44A3 | 126969 | 0 | 5 | 15 | |
| TCGA | SLC44A3 | 126969 | 6 | 24 | 66 |
Total number of gains: 24; Total number of losses: 66; Total Number of normals: 398.
Somatic mutations of SLC44A3:
Generating mutation plots.
Highly correlated genes for SLC44A3:
Showing top 20/1657 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC44A3 | BLNK | 0.805591 | 7 | 0 | 7 |
| SLC44A3 | CA13 | 0.800941 | 3 | 0 | 3 |
| SLC44A3 | DLG2 | 0.773181 | 6 | 0 | 6 |
| SLC44A3 | PEX2 | 0.77227 | 3 | 0 | 3 |
| SLC44A3 | ZNF626 | 0.770791 | 4 | 0 | 4 |
| SLC44A3 | LMBRD1 | 0.766631 | 6 | 0 | 6 |
| SLC44A3 | KAT2B | 0.764294 | 7 | 0 | 6 |
| SLC44A3 | SLC10A5 | 0.764157 | 3 | 0 | 3 |
| SLC44A3 | ACAA1 | 0.76302 | 5 | 0 | 5 |
| SLC44A3 | VSIG2 | 0.762262 | 6 | 0 | 6 |
| SLC44A3 | SIM2 | 0.758188 | 7 | 0 | 7 |
| SLC44A3 | SCP2 | 0.756681 | 8 | 0 | 7 |
| SLC44A3 | C1orf116 | 0.756188 | 6 | 0 | 6 |
| SLC44A3 | CCDC6 | 0.756134 | 7 | 0 | 7 |
| SLC44A3 | PADI1 | 0.756077 | 4 | 0 | 4 |
| SLC44A3 | PEA15 | 0.755554 | 3 | 0 | 3 |
| SLC44A3 | USP6NL | 0.75535 | 7 | 0 | 7 |
| SLC44A3 | RMND5B | 0.754522 | 7 | 0 | 7 |
| SLC44A3 | STXBP5 | 0.754088 | 7 | 0 | 7 |
| SLC44A3 | CMPK1 | 0.753151 | 7 | 0 | 7 |
For details and further investigation, click here
