| Full name: CCHC-type zinc finger nucleic acid binding protein | Alias Symbol: RNF163|ZCCHC22|CNBP1 | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 7555 | HGNC ID: HGNC:13164 | Ensembl Gene: ENSG00000169714 | OMIM ID: 116955 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CNBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNBP | 7555 | 206158_s_at | 0.1529 | 0.4861 | |
| GSE20347 | CNBP | 7555 | 206158_s_at | 0.3705 | 0.0007 | |
| GSE23400 | CNBP | 7555 | 206158_s_at | 0.4881 | 0.0000 | |
| GSE26886 | CNBP | 7555 | 206158_s_at | -0.0821 | 0.6284 | |
| GSE29001 | CNBP | 7555 | 206158_s_at | 0.4383 | 0.1347 | |
| GSE38129 | CNBP | 7555 | 206158_s_at | 0.2963 | 0.0047 | |
| GSE45670 | CNBP | 7555 | 206158_s_at | 0.0772 | 0.5705 | |
| GSE63941 | CNBP | 7555 | 206158_s_at | 0.2266 | 0.5441 | |
| GSE77861 | CNBP | 7555 | 206158_s_at | 0.4231 | 0.1043 | |
| GSE97050 | CNBP | 7555 | A_23_P84651 | -0.0430 | 0.8913 | |
| SRP007169 | CNBP | 7555 | RNAseq | -0.1306 | 0.7000 | |
| SRP008496 | CNBP | 7555 | RNAseq | 0.1514 | 0.5091 | |
| SRP064894 | CNBP | 7555 | RNAseq | 0.0880 | 0.5622 | |
| SRP133303 | CNBP | 7555 | RNAseq | 0.2110 | 0.0698 | |
| SRP159526 | CNBP | 7555 | RNAseq | 0.1910 | 0.3454 | |
| SRP193095 | CNBP | 7555 | RNAseq | -0.0292 | 0.8003 | |
| SRP219564 | CNBP | 7555 | RNAseq | -0.2425 | 0.1302 | |
| TCGA | CNBP | 7555 | RNAseq | 0.0749 | 0.0507 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CNBP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CNBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNBP | 7555 | 17 | 0 | 13 | |
| GSE20123 | CNBP | 7555 | 17 | 0 | 13 | |
| GSE43470 | CNBP | 7555 | 19 | 0 | 24 | |
| GSE46452 | CNBP | 7555 | 14 | 5 | 40 | |
| GSE47630 | CNBP | 7555 | 18 | 3 | 19 | |
| GSE54993 | CNBP | 7555 | 2 | 8 | 60 | |
| GSE54994 | CNBP | 7555 | 32 | 3 | 18 | |
| GSE60625 | CNBP | 7555 | 0 | 6 | 5 | |
| GSE74703 | CNBP | 7555 | 17 | 0 | 19 | |
| GSE74704 | CNBP | 7555 | 13 | 0 | 7 | |
| TCGA | CNBP | 7555 | 58 | 5 | 33 |
Total number of gains: 207; Total number of losses: 30; Total Number of normals: 251.
Somatic mutations of CNBP:
Generating mutation plots.
Highly correlated genes for CNBP:
Showing top 20/1069 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNBP | PDE8A | 0.747348 | 3 | 0 | 3 |
| CNBP | ARL13B | 0.740516 | 5 | 0 | 4 |
| CNBP | TOMM40L | 0.731957 | 3 | 0 | 3 |
| CNBP | PET117 | 0.726498 | 3 | 0 | 3 |
| CNBP | PHB | 0.719292 | 6 | 0 | 6 |
| CNBP | USP24 | 0.707024 | 3 | 0 | 3 |
| CNBP | DARS2 | 0.700358 | 3 | 0 | 3 |
| CNBP | ZMYM6 | 0.693335 | 4 | 0 | 4 |
| CNBP | ZNF830 | 0.692693 | 3 | 0 | 3 |
| CNBP | ISCA2 | 0.691912 | 3 | 0 | 3 |
| CNBP | MRPL3 | 0.689911 | 10 | 0 | 8 |
| CNBP | NBAS | 0.688325 | 4 | 0 | 3 |
| CNBP | ATP6V1C1 | 0.686389 | 8 | 0 | 7 |
| CNBP | THAP11 | 0.686278 | 7 | 0 | 7 |
| CNBP | CBX6 | 0.685451 | 3 | 0 | 3 |
| CNBP | HAT1 | 0.684854 | 9 | 0 | 9 |
| CNBP | SSR3 | 0.684438 | 7 | 0 | 6 |
| CNBP | LRRC58 | 0.68386 | 5 | 0 | 5 |
| CNBP | ARMC1 | 0.683691 | 7 | 0 | 6 |
| CNBP | SRI | 0.681456 | 4 | 0 | 4 |
For details and further investigation, click here
