| Full name: THAP domain containing 11 | Alias Symbol: HRIHFB2206|CTG-B45d|CTG-B43a | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 57215 | HGNC ID: HGNC:23194 | Ensembl Gene: ENSG00000168286 | OMIM ID: 609119 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of THAP11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THAP11 | 57215 | 212910_at | 0.1858 | 0.6802 | |
| GSE20347 | THAP11 | 57215 | 212910_at | 0.2177 | 0.0498 | |
| GSE23400 | THAP11 | 57215 | 212910_at | 0.1440 | 0.0012 | |
| GSE26886 | THAP11 | 57215 | 212910_at | 0.0474 | 0.8386 | |
| GSE29001 | THAP11 | 57215 | 212910_at | 0.2072 | 0.3762 | |
| GSE38129 | THAP11 | 57215 | 212910_at | 0.1655 | 0.0864 | |
| GSE45670 | THAP11 | 57215 | 212910_at | 0.0953 | 0.4801 | |
| GSE53622 | THAP11 | 57215 | 130748 | 0.1029 | 0.0832 | |
| GSE53624 | THAP11 | 57215 | 130748 | 0.0498 | 0.5019 | |
| GSE63941 | THAP11 | 57215 | 212910_at | 0.7409 | 0.0496 | |
| GSE77861 | THAP11 | 57215 | 212910_at | 0.2720 | 0.0777 | |
| GSE97050 | THAP11 | 57215 | A_24_P365954 | 0.1973 | 0.4471 | |
| SRP007169 | THAP11 | 57215 | RNAseq | -0.2072 | 0.5768 | |
| SRP008496 | THAP11 | 57215 | RNAseq | -0.0811 | 0.6810 | |
| SRP064894 | THAP11 | 57215 | RNAseq | 0.0817 | 0.6885 | |
| SRP133303 | THAP11 | 57215 | RNAseq | 0.2759 | 0.0810 | |
| SRP159526 | THAP11 | 57215 | RNAseq | 0.3089 | 0.1933 | |
| SRP193095 | THAP11 | 57215 | RNAseq | 0.2689 | 0.0303 | |
| SRP219564 | THAP11 | 57215 | RNAseq | 0.0176 | 0.9504 | |
| TCGA | THAP11 | 57215 | RNAseq | 0.0817 | 0.1190 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THAP11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THAP11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THAP11 | 57215 | 9 | 2 | 19 | |
| GSE20123 | THAP11 | 57215 | 9 | 2 | 19 | |
| GSE43470 | THAP11 | 57215 | 1 | 9 | 33 | |
| GSE46452 | THAP11 | 57215 | 38 | 1 | 20 | |
| GSE47630 | THAP11 | 57215 | 11 | 8 | 21 | |
| GSE54993 | THAP11 | 57215 | 2 | 4 | 64 | |
| GSE54994 | THAP11 | 57215 | 8 | 10 | 35 | |
| GSE60625 | THAP11 | 57215 | 4 | 0 | 7 | |
| GSE74703 | THAP11 | 57215 | 1 | 6 | 29 | |
| GSE74704 | THAP11 | 57215 | 5 | 1 | 14 | |
| TCGA | THAP11 | 57215 | 28 | 13 | 55 |
Total number of gains: 116; Total number of losses: 56; Total Number of normals: 316.
Somatic mutations of THAP11:
Generating mutation plots.
Highly correlated genes for THAP11:
Showing top 20/903 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THAP11 | PIP4K2C | 0.779814 | 3 | 0 | 3 |
| THAP11 | CNOT1 | 0.758226 | 3 | 0 | 3 |
| THAP11 | POLB | 0.752598 | 3 | 0 | 3 |
| THAP11 | LRRC58 | 0.747411 | 3 | 0 | 3 |
| THAP11 | IRF2BPL | 0.74467 | 4 | 0 | 4 |
| THAP11 | FBXO39 | 0.730142 | 3 | 0 | 3 |
| THAP11 | CCDC124 | 0.72698 | 3 | 0 | 3 |
| THAP11 | ELP2 | 0.72567 | 3 | 0 | 3 |
| THAP11 | GMCL1 | 0.725473 | 4 | 0 | 3 |
| THAP11 | AP1AR | 0.721965 | 3 | 0 | 3 |
| THAP11 | ACTR2 | 0.716787 | 3 | 0 | 3 |
| THAP11 | TMEM60 | 0.715483 | 5 | 0 | 4 |
| THAP11 | TCEANC2 | 0.710944 | 3 | 0 | 3 |
| THAP11 | RSRC2 | 0.709776 | 3 | 0 | 3 |
| THAP11 | BAG4 | 0.706015 | 4 | 0 | 3 |
| THAP11 | NUP50 | 0.704314 | 4 | 0 | 3 |
| THAP11 | AQR | 0.703454 | 3 | 0 | 3 |
| THAP11 | ZNF70 | 0.701766 | 3 | 0 | 3 |
| THAP11 | RIN2 | 0.700814 | 4 | 0 | 4 |
| THAP11 | KDM5B | 0.700088 | 3 | 0 | 3 |
For details and further investigation, click here
