| Full name: signal sequence receptor subunit 3 | Alias Symbol: TRAPG | ||
| Type: protein-coding gene | Cytoband: 3q25.31 | ||
| Entrez ID: 6747 | HGNC ID: HGNC:11325 | Ensembl Gene: ENSG00000114850 | OMIM ID: 606213 |
| Drug and gene relationship at DGIdb | |||
Expression of SSR3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSR3 | 6747 | 222411_s_at | 0.4297 | 0.2409 | |
| GSE20347 | SSR3 | 6747 | 217790_s_at | 0.4955 | 0.0176 | |
| GSE23400 | SSR3 | 6747 | 217790_s_at | 0.3799 | 0.0000 | |
| GSE26886 | SSR3 | 6747 | 222411_s_at | 0.2733 | 0.1501 | |
| GSE29001 | SSR3 | 6747 | 217790_s_at | 0.4722 | 0.0252 | |
| GSE38129 | SSR3 | 6747 | 217790_s_at | 0.4972 | 0.0023 | |
| GSE45670 | SSR3 | 6747 | 222411_s_at | 0.7310 | 0.0017 | |
| GSE53622 | SSR3 | 6747 | 33743 | 0.3756 | 0.0000 | |
| GSE53624 | SSR3 | 6747 | 33743 | 0.6536 | 0.0000 | |
| GSE63941 | SSR3 | 6747 | 222411_s_at | 0.4162 | 0.4653 | |
| GSE77861 | SSR3 | 6747 | 222411_s_at | 0.3701 | 0.1536 | |
| GSE97050 | SSR3 | 6747 | A_24_P319942 | 0.1434 | 0.6804 | |
| SRP007169 | SSR3 | 6747 | RNAseq | -0.0400 | 0.9146 | |
| SRP008496 | SSR3 | 6747 | RNAseq | 0.2915 | 0.1665 | |
| SRP064894 | SSR3 | 6747 | RNAseq | 0.8704 | 0.0000 | |
| SRP133303 | SSR3 | 6747 | RNAseq | 1.1788 | 0.0000 | |
| SRP159526 | SSR3 | 6747 | RNAseq | 1.4166 | 0.0005 | |
| SRP193095 | SSR3 | 6747 | RNAseq | 0.3817 | 0.0197 | |
| SRP219564 | SSR3 | 6747 | RNAseq | 0.3804 | 0.5069 | |
| TCGA | SSR3 | 6747 | RNAseq | 0.0149 | 0.7294 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SSR3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSR3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSR3 | 6747 | 21 | 1 | 8 | |
| GSE20123 | SSR3 | 6747 | 21 | 1 | 8 | |
| GSE43470 | SSR3 | 6747 | 23 | 0 | 20 | |
| GSE46452 | SSR3 | 6747 | 18 | 2 | 39 | |
| GSE47630 | SSR3 | 6747 | 19 | 3 | 18 | |
| GSE54993 | SSR3 | 6747 | 1 | 11 | 58 | |
| GSE54994 | SSR3 | 6747 | 38 | 1 | 14 | |
| GSE60625 | SSR3 | 6747 | 0 | 6 | 5 | |
| GSE74703 | SSR3 | 6747 | 20 | 0 | 16 | |
| GSE74704 | SSR3 | 6747 | 14 | 0 | 6 | |
| TCGA | SSR3 | 6747 | 73 | 1 | 22 |
Total number of gains: 248; Total number of losses: 26; Total Number of normals: 214.
Somatic mutations of SSR3:
Generating mutation plots.
Highly correlated genes for SSR3:
Showing top 20/1383 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSR3 | MRPL10 | 0.767341 | 3 | 0 | 3 |
| SSR3 | ISY1 | 0.755282 | 3 | 0 | 3 |
| SSR3 | ACY1 | 0.742954 | 3 | 0 | 3 |
| SSR3 | TMEM167A | 0.741926 | 3 | 0 | 3 |
| SSR3 | FXR1 | 0.737935 | 8 | 0 | 8 |
| SSR3 | GGNBP2 | 0.731871 | 3 | 0 | 3 |
| SSR3 | SLC35B2 | 0.716928 | 3 | 0 | 3 |
| SSR3 | E2F5 | 0.716112 | 3 | 0 | 3 |
| SSR3 | NIPA1 | 0.716092 | 4 | 0 | 4 |
| SSR3 | NSUN3 | 0.715104 | 5 | 0 | 5 |
| SSR3 | RAB34 | 0.71011 | 3 | 0 | 3 |
| SSR3 | ZDHHC16 | 0.708186 | 3 | 0 | 3 |
| SSR3 | SEC22A | 0.706984 | 6 | 0 | 5 |
| SSR3 | TYW5 | 0.705219 | 3 | 0 | 3 |
| SSR3 | ZNF275 | 0.704325 | 3 | 0 | 3 |
| SSR3 | DNAJC19 | 0.70206 | 4 | 0 | 4 |
| SSR3 | C1orf226 | 0.699832 | 4 | 0 | 3 |
| SSR3 | CENPA | 0.699758 | 7 | 0 | 6 |
| SSR3 | RAB7A | 0.698129 | 3 | 0 | 3 |
| SSR3 | FADS1 | 0.695834 | 3 | 0 | 3 |
For details and further investigation, click here
