| Full name: contactin 1 | Alias Symbol: F3|GP135 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 1272 | HGNC ID: HGNC:2171 | Ensembl Gene: ENSG00000018236 | OMIM ID: 600016 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CNTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTN1 | 1272 | 227209_at | 0.8739 | 0.6253 | |
| GSE20347 | CNTN1 | 1272 | 211203_s_at | 0.2444 | 0.0097 | |
| GSE23400 | CNTN1 | 1272 | 211203_s_at | 0.0404 | 0.6262 | |
| GSE26886 | CNTN1 | 1272 | 227209_at | 0.9119 | 0.1864 | |
| GSE29001 | CNTN1 | 1272 | 211203_s_at | 0.1174 | 0.6058 | |
| GSE38129 | CNTN1 | 1272 | 211203_s_at | 0.1670 | 0.1597 | |
| GSE45670 | CNTN1 | 1272 | 227209_at | 0.6070 | 0.3359 | |
| GSE53622 | CNTN1 | 1272 | 46851 | 0.1773 | 0.4776 | |
| GSE53624 | CNTN1 | 1272 | 46851 | 0.6500 | 0.0000 | |
| GSE63941 | CNTN1 | 1272 | 211203_s_at | 3.1267 | 0.0454 | |
| GSE77861 | CNTN1 | 1272 | 227209_at | 0.6738 | 0.0881 | |
| GSE97050 | CNTN1 | 1272 | A_33_P3409090 | -0.0035 | 0.9975 | |
| SRP007169 | CNTN1 | 1272 | RNAseq | 2.3467 | 0.0003 | |
| SRP008496 | CNTN1 | 1272 | RNAseq | 2.2965 | 0.0000 | |
| SRP064894 | CNTN1 | 1272 | RNAseq | 0.3206 | 0.4086 | |
| SRP133303 | CNTN1 | 1272 | RNAseq | 1.6060 | 0.0016 | |
| SRP159526 | CNTN1 | 1272 | RNAseq | 0.4372 | 0.4037 | |
| SRP193095 | CNTN1 | 1272 | RNAseq | 1.3642 | 0.0001 | |
| SRP219564 | CNTN1 | 1272 | RNAseq | 0.0787 | 0.9295 | |
| TCGA | CNTN1 | 1272 | RNAseq | -0.0067 | 0.9825 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CNTN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTN1 | 1272 | 6 | 1 | 23 | |
| GSE20123 | CNTN1 | 1272 | 6 | 1 | 23 | |
| GSE43470 | CNTN1 | 1272 | 4 | 4 | 35 | |
| GSE46452 | CNTN1 | 1272 | 8 | 1 | 50 | |
| GSE47630 | CNTN1 | 1272 | 11 | 2 | 27 | |
| GSE54993 | CNTN1 | 1272 | 0 | 8 | 62 | |
| GSE54994 | CNTN1 | 1272 | 7 | 1 | 45 | |
| GSE60625 | CNTN1 | 1272 | 0 | 0 | 11 | |
| GSE74703 | CNTN1 | 1272 | 4 | 2 | 30 | |
| GSE74704 | CNTN1 | 1272 | 2 | 1 | 17 | |
| TCGA | CNTN1 | 1272 | 16 | 14 | 66 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of CNTN1:
Generating mutation plots.
Highly correlated genes for CNTN1:
Showing top 20/225 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTN1 | ABCG1 | 0.778043 | 3 | 0 | 3 |
| CNTN1 | C1orf226 | 0.742554 | 3 | 0 | 3 |
| CNTN1 | ARL13B | 0.731563 | 3 | 0 | 3 |
| CNTN1 | NUTF2 | 0.711339 | 3 | 0 | 3 |
| CNTN1 | EPHA4 | 0.701334 | 3 | 0 | 3 |
| CNTN1 | PDPR | 0.68316 | 4 | 0 | 4 |
| CNTN1 | TERF2 | 0.6809 | 3 | 0 | 3 |
| CNTN1 | VASP | 0.678779 | 4 | 0 | 4 |
| CNTN1 | SAG | 0.673837 | 3 | 0 | 3 |
| CNTN1 | MRPL10 | 0.673454 | 4 | 0 | 3 |
| CNTN1 | TGFBR1 | 0.665163 | 4 | 0 | 4 |
| CNTN1 | ATXN1L | 0.663907 | 4 | 0 | 3 |
| CNTN1 | ZNF174 | 0.662338 | 3 | 0 | 3 |
| CNTN1 | EGFR | 0.660293 | 3 | 0 | 3 |
| CNTN1 | MOB3C | 0.657608 | 4 | 0 | 3 |
| CNTN1 | NDUFV1 | 0.655868 | 3 | 0 | 3 |
| CNTN1 | ZNF827 | 0.653474 | 3 | 0 | 3 |
| CNTN1 | NUCKS1 | 0.652263 | 3 | 0 | 3 |
| CNTN1 | CHMP1B | 0.650911 | 3 | 0 | 3 |
| CNTN1 | TET1 | 0.650291 | 3 | 0 | 3 |
For details and further investigation, click here
