| Full name: telomeric repeat binding factor 2 | Alias Symbol: TRF2 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 7014 | HGNC ID: HGNC:11729 | Ensembl Gene: ENSG00000132604 | OMIM ID: 602027 |
| Drug and gene relationship at DGIdb | |||
Expression of TERF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TERF2 | 7014 | 203611_at | 0.0477 | 0.9394 | |
| GSE20347 | TERF2 | 7014 | 203611_at | 0.1187 | 0.3925 | |
| GSE23400 | TERF2 | 7014 | 203611_at | 0.1825 | 0.0003 | |
| GSE26886 | TERF2 | 7014 | 203611_at | 0.0423 | 0.8939 | |
| GSE29001 | TERF2 | 7014 | 203611_at | 0.2343 | 0.3634 | |
| GSE38129 | TERF2 | 7014 | 203611_at | 0.0115 | 0.9420 | |
| GSE45670 | TERF2 | 7014 | 203611_at | -0.0288 | 0.8502 | |
| GSE63941 | TERF2 | 7014 | 203611_at | 1.6641 | 0.0032 | |
| GSE77861 | TERF2 | 7014 | 203611_at | 0.2913 | 0.1023 | |
| GSE97050 | TERF2 | 7014 | A_23_P417200 | 0.1157 | 0.6380 | |
| SRP007169 | TERF2 | 7014 | RNAseq | -0.3149 | 0.3935 | |
| SRP008496 | TERF2 | 7014 | RNAseq | -0.2126 | 0.3813 | |
| SRP064894 | TERF2 | 7014 | RNAseq | -0.0568 | 0.5709 | |
| SRP133303 | TERF2 | 7014 | RNAseq | 0.1203 | 0.2542 | |
| SRP159526 | TERF2 | 7014 | RNAseq | 0.1498 | 0.4977 | |
| SRP193095 | TERF2 | 7014 | RNAseq | 0.1930 | 0.0988 | |
| SRP219564 | TERF2 | 7014 | RNAseq | -0.0260 | 0.9251 | |
| TCGA | TERF2 | 7014 | RNAseq | -0.0079 | 0.8757 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TERF2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TERF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TERF2 | 7014 | 8 | 1 | 21 | |
| GSE20123 | TERF2 | 7014 | 8 | 1 | 21 | |
| GSE43470 | TERF2 | 7014 | 2 | 7 | 34 | |
| GSE46452 | TERF2 | 7014 | 38 | 1 | 20 | |
| GSE47630 | TERF2 | 7014 | 11 | 8 | 21 | |
| GSE54993 | TERF2 | 7014 | 2 | 4 | 64 | |
| GSE54994 | TERF2 | 7014 | 8 | 10 | 35 | |
| GSE60625 | TERF2 | 7014 | 4 | 0 | 7 | |
| GSE74703 | TERF2 | 7014 | 2 | 4 | 30 | |
| GSE74704 | TERF2 | 7014 | 4 | 0 | 16 | |
| TCGA | TERF2 | 7014 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 48; Total Number of normals: 324.
Somatic mutations of TERF2:
Generating mutation plots.
Highly correlated genes for TERF2:
Showing top 20/549 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TERF2 | PIP4K2B | 0.810664 | 3 | 0 | 3 |
| TERF2 | ZNF691 | 0.79923 | 3 | 0 | 3 |
| TERF2 | PCDH12 | 0.786032 | 3 | 0 | 3 |
| TERF2 | NECAP1 | 0.776932 | 3 | 0 | 3 |
| TERF2 | CMIP | 0.770321 | 3 | 0 | 3 |
| TERF2 | RRNAD1 | 0.768378 | 3 | 0 | 3 |
| TERF2 | MCCC2 | 0.767936 | 3 | 0 | 3 |
| TERF2 | CREB3 | 0.765248 | 3 | 0 | 3 |
| TERF2 | ZNF317 | 0.758645 | 3 | 0 | 3 |
| TERF2 | NIPA1 | 0.757784 | 3 | 0 | 3 |
| TERF2 | COMMD2 | 0.754101 | 3 | 0 | 3 |
| TERF2 | C19orf54 | 0.752952 | 3 | 0 | 3 |
| TERF2 | MED9 | 0.752777 | 3 | 0 | 3 |
| TERF2 | WDR5 | 0.745552 | 3 | 0 | 3 |
| TERF2 | PPP1R35 | 0.741502 | 4 | 0 | 4 |
| TERF2 | C12orf45 | 0.73979 | 3 | 0 | 3 |
| TERF2 | PRKCSH | 0.73279 | 4 | 0 | 4 |
| TERF2 | DUSP18 | 0.731708 | 3 | 0 | 3 |
| TERF2 | RAVER1 | 0.730256 | 3 | 0 | 3 |
| TERF2 | EPPK1 | 0.726376 | 3 | 0 | 3 |
For details and further investigation, click here
