| Full name: ATP binding cassette subfamily G member 1 | Alias Symbol: ABC8 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 9619 | HGNC ID: HGNC:73 | Ensembl Gene: ENSG00000160179 | OMIM ID: 603076 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCG1 | 9619 | 204567_s_at | 0.8713 | 0.2047 | |
| GSE20347 | ABCG1 | 9619 | 204567_s_at | 1.4585 | 0.0009 | |
| GSE23400 | ABCG1 | 9619 | 211113_s_at | 0.1931 | 0.0001 | |
| GSE26886 | ABCG1 | 9619 | 204567_s_at | 0.3800 | 0.5746 | |
| GSE29001 | ABCG1 | 9619 | 204567_s_at | 1.1645 | 0.0303 | |
| GSE38129 | ABCG1 | 9619 | 204567_s_at | 1.3114 | 0.0002 | |
| GSE45670 | ABCG1 | 9619 | 204567_s_at | 1.2003 | 0.0003 | |
| GSE53622 | ABCG1 | 9619 | 68815 | 0.5331 | 0.0004 | |
| GSE53624 | ABCG1 | 9619 | 68815 | 0.7338 | 0.0000 | |
| GSE63941 | ABCG1 | 9619 | 204567_s_at | 1.4290 | 0.4021 | |
| GSE77861 | ABCG1 | 9619 | 211113_s_at | 0.2605 | 0.1097 | |
| GSE97050 | ABCG1 | 9619 | A_23_P166297 | -0.0812 | 0.7070 | |
| SRP007169 | ABCG1 | 9619 | RNAseq | 1.7405 | 0.0006 | |
| SRP008496 | ABCG1 | 9619 | RNAseq | 0.4141 | 0.2677 | |
| SRP064894 | ABCG1 | 9619 | RNAseq | 1.0300 | 0.0002 | |
| SRP133303 | ABCG1 | 9619 | RNAseq | 0.8790 | 0.0000 | |
| SRP159526 | ABCG1 | 9619 | RNAseq | 1.8801 | 0.0000 | |
| SRP193095 | ABCG1 | 9619 | RNAseq | -0.0145 | 0.9590 | |
| SRP219564 | ABCG1 | 9619 | RNAseq | 1.2215 | 0.0150 | |
| TCGA | ABCG1 | 9619 | RNAseq | -0.1728 | 0.0752 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by ABCG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCG1 | 9619 | 2 | 8 | 20 | |
| GSE20123 | ABCG1 | 9619 | 2 | 8 | 20 | |
| GSE43470 | ABCG1 | 9619 | 0 | 13 | 30 | |
| GSE46452 | ABCG1 | 9619 | 1 | 21 | 37 | |
| GSE47630 | ABCG1 | 9619 | 6 | 17 | 17 | |
| GSE54993 | ABCG1 | 9619 | 8 | 1 | 61 | |
| GSE54994 | ABCG1 | 9619 | 3 | 8 | 42 | |
| GSE60625 | ABCG1 | 9619 | 0 | 0 | 11 | |
| GSE74703 | ABCG1 | 9619 | 0 | 10 | 26 | |
| GSE74704 | ABCG1 | 9619 | 1 | 4 | 15 | |
| TCGA | ABCG1 | 9619 | 7 | 41 | 48 |
Total number of gains: 30; Total number of losses: 131; Total Number of normals: 327.
Somatic mutations of ABCG1:
Generating mutation plots.
Highly correlated genes for ABCG1:
Showing top 20/601 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCG1 | CNTN1 | 0.778043 | 3 | 0 | 3 |
| ABCG1 | PDK1 | 0.774035 | 3 | 0 | 3 |
| ABCG1 | C2orf69 | 0.752437 | 3 | 0 | 3 |
| ABCG1 | NEIL2 | 0.728226 | 3 | 0 | 3 |
| ABCG1 | NUS1 | 0.72069 | 3 | 0 | 3 |
| ABCG1 | CCDC127 | 0.716865 | 4 | 0 | 4 |
| ABCG1 | RLIM | 0.712906 | 3 | 0 | 3 |
| ABCG1 | RNF115 | 0.703553 | 3 | 0 | 3 |
| ABCG1 | RBM12 | 0.699526 | 3 | 0 | 3 |
| ABCG1 | SUPT16H | 0.69926 | 6 | 0 | 5 |
| ABCG1 | CERCAM | 0.694226 | 3 | 0 | 3 |
| ABCG1 | IFIH1 | 0.686186 | 3 | 0 | 3 |
| ABCG1 | ORC2 | 0.673998 | 4 | 0 | 3 |
| ABCG1 | DERL1 | 0.673922 | 4 | 0 | 4 |
| ABCG1 | COA5 | 0.671712 | 3 | 0 | 3 |
| ABCG1 | RNF139 | 0.671578 | 3 | 0 | 3 |
| ABCG1 | ASB2 | 0.664731 | 3 | 0 | 3 |
| ABCG1 | MAML1 | 0.658917 | 3 | 0 | 3 |
| ABCG1 | ZNF3 | 0.658811 | 5 | 0 | 5 |
| ABCG1 | CHORDC1 | 0.656683 | 3 | 0 | 3 |
For details and further investigation, click here
