| Full name: contactin 3 | Alias Symbol: BIG-1 | ||
| Type: protein-coding gene | Cytoband: 3p12.3 | ||
| Entrez ID: 5067 | HGNC ID: HGNC:2173 | Ensembl Gene: ENSG00000113805 | OMIM ID: 601325 |
| Drug and gene relationship at DGIdb | |||
Expression of CNTN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTN3 | 5067 | 229831_at | -0.8303 | 0.4278 | |
| GSE26886 | CNTN3 | 5067 | 229831_at | 0.0187 | 0.8972 | |
| GSE45670 | CNTN3 | 5067 | 229831_at | -1.3782 | 0.0002 | |
| GSE53622 | CNTN3 | 5067 | 111970 | -0.3860 | 0.0126 | |
| GSE53624 | CNTN3 | 5067 | 111970 | -0.3249 | 0.0053 | |
| GSE63941 | CNTN3 | 5067 | 229831_at | -4.4186 | 0.0001 | |
| GSE77861 | CNTN3 | 5067 | 229831_at | 0.0019 | 0.9823 | |
| TCGA | CNTN3 | 5067 | RNAseq | -2.6587 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CNTN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTN3 | 5067 | 1 | 18 | 11 | |
| GSE20123 | CNTN3 | 5067 | 1 | 18 | 11 | |
| GSE43470 | CNTN3 | 5067 | 0 | 20 | 23 | |
| GSE46452 | CNTN3 | 5067 | 2 | 17 | 40 | |
| GSE47630 | CNTN3 | 5067 | 1 | 23 | 16 | |
| GSE54993 | CNTN3 | 5067 | 4 | 3 | 63 | |
| GSE54994 | CNTN3 | 5067 | 1 | 31 | 21 | |
| GSE60625 | CNTN3 | 5067 | 3 | 1 | 7 | |
| GSE74703 | CNTN3 | 5067 | 0 | 17 | 19 | |
| GSE74704 | CNTN3 | 5067 | 1 | 13 | 6 | |
| TCGA | CNTN3 | 5067 | 1 | 79 | 16 |
Total number of gains: 15; Total number of losses: 240; Total Number of normals: 233.
Somatic mutations of CNTN3:
Generating mutation plots.
Highly correlated genes for CNTN3:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTN3 | PCDH9 | 0.87457 | 3 | 0 | 3 |
| CNTN3 | TBX5 | 0.871942 | 3 | 0 | 3 |
| CNTN3 | TBX5-AS1 | 0.835337 | 3 | 0 | 3 |
| CNTN3 | MGARP | 0.816199 | 3 | 0 | 3 |
| CNTN3 | HABP4 | 0.804938 | 3 | 0 | 3 |
| CNTN3 | ITGA1 | 0.80285 | 4 | 0 | 4 |
| CNTN3 | STARD9 | 0.799104 | 3 | 0 | 3 |
| CNTN3 | CACNA1C | 0.799056 | 3 | 0 | 3 |
| CNTN3 | GYPC | 0.787771 | 3 | 0 | 3 |
| CNTN3 | SGIP1 | 0.78712 | 3 | 0 | 3 |
| CNTN3 | INMT | 0.772731 | 3 | 0 | 3 |
| CNTN3 | MAP1A | 0.771266 | 3 | 0 | 3 |
| CNTN3 | PEG3 | 0.769936 | 3 | 0 | 3 |
| CNTN3 | FGF7 | 0.761687 | 4 | 0 | 4 |
| CNTN3 | OSR1 | 0.750389 | 3 | 0 | 3 |
| CNTN3 | PDE1C | 0.743163 | 3 | 0 | 3 |
| CNTN3 | SYNC | 0.738925 | 3 | 0 | 3 |
| CNTN3 | TIMP3 | 0.738703 | 4 | 0 | 4 |
| CNTN3 | LINC00472 | 0.738336 | 3 | 0 | 3 |
| CNTN3 | GPRASP1 | 0.730186 | 3 | 0 | 3 |
For details and further investigation, click here
