| Full name: odd-skipped related transcription factor 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p24.1 | ||
| Entrez ID: 130497 | HGNC ID: HGNC:8111 | Ensembl Gene: ENSG00000143867 | OMIM ID: 608891 |
| Drug and gene relationship at DGIdb | |||
Expression of OSR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSR1 | 130497 | 228399_at | -0.1237 | 0.8885 | |
| GSE26886 | OSR1 | 130497 | 228399_at | 0.6839 | 0.0024 | |
| GSE45670 | OSR1 | 130497 | 228399_at | -0.9550 | 0.0003 | |
| GSE63941 | OSR1 | 130497 | 228399_at | -1.4539 | 0.0019 | |
| GSE77861 | OSR1 | 130497 | 228399_at | 0.1652 | 0.1870 | |
| GSE97050 | OSR1 | 130497 | A_23_P323272 | -0.4479 | 0.3127 | |
| SRP064894 | OSR1 | 130497 | RNAseq | 1.0694 | 0.0686 | |
| SRP133303 | OSR1 | 130497 | RNAseq | -1.1070 | 0.0632 | |
| SRP159526 | OSR1 | 130497 | RNAseq | 3.7237 | 0.0002 | |
| SRP219564 | OSR1 | 130497 | RNAseq | -0.3697 | 0.7440 | |
| TCGA | OSR1 | 130497 | RNAseq | -0.7697 | 0.0031 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by OSR1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of OSR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSR1 | 130497 | 9 | 2 | 19 | |
| GSE20123 | OSR1 | 130497 | 9 | 2 | 19 | |
| GSE43470 | OSR1 | 130497 | 2 | 0 | 41 | |
| GSE46452 | OSR1 | 130497 | 3 | 4 | 52 | |
| GSE47630 | OSR1 | 130497 | 7 | 0 | 33 | |
| GSE54993 | OSR1 | 130497 | 0 | 7 | 63 | |
| GSE54994 | OSR1 | 130497 | 11 | 0 | 42 | |
| GSE60625 | OSR1 | 130497 | 0 | 3 | 8 | |
| GSE74703 | OSR1 | 130497 | 2 | 0 | 34 | |
| GSE74704 | OSR1 | 130497 | 8 | 2 | 10 | |
| TCGA | OSR1 | 130497 | 37 | 2 | 57 |
Total number of gains: 88; Total number of losses: 22; Total Number of normals: 378.
Somatic mutations of OSR1:
Generating mutation plots.
Highly correlated genes for OSR1:
Showing top 20/408 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSR1 | SEMA3E | 0.775591 | 3 | 0 | 3 |
| OSR1 | CNTN3 | 0.750389 | 3 | 0 | 3 |
| OSR1 | TBX5-AS1 | 0.741376 | 4 | 0 | 4 |
| OSR1 | MYOC | 0.74002 | 3 | 0 | 3 |
| OSR1 | NBPF20 | 0.734467 | 3 | 0 | 3 |
| OSR1 | DENND2A | 0.733211 | 5 | 0 | 5 |
| OSR1 | TMEM255A | 0.720225 | 3 | 0 | 3 |
| OSR1 | DACT3 | 0.713613 | 6 | 0 | 6 |
| OSR1 | ADAMTSL1 | 0.712989 | 4 | 0 | 4 |
| OSR1 | ABCA9 | 0.712625 | 3 | 0 | 3 |
| OSR1 | ITGBL1 | 0.711721 | 4 | 0 | 4 |
| OSR1 | KCND2 | 0.709164 | 3 | 0 | 3 |
| OSR1 | FBLN2 | 0.704326 | 4 | 0 | 4 |
| OSR1 | C9orf24 | 0.703957 | 3 | 0 | 3 |
| OSR1 | CDH11 | 0.69926 | 3 | 0 | 3 |
| OSR1 | FAR2 | 0.698716 | 3 | 0 | 3 |
| OSR1 | SHISA3 | 0.695101 | 4 | 0 | 3 |
| OSR1 | STMN3 | 0.687021 | 3 | 0 | 3 |
| OSR1 | PABPC5 | 0.685278 | 3 | 0 | 3 |
| OSR1 | SOD3 | 0.685209 | 5 | 0 | 4 |
For details and further investigation, click here
