| Full name: glycophorin C (Gerbich blood group) | Alias Symbol: GPC|GYPD|Ge|CD236|CD236R | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 2995 | HGNC ID: HGNC:4704 | Ensembl Gene: ENSG00000136732 | OMIM ID: 110750 |
| Drug and gene relationship at DGIdb | |||
Expression of GYPC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GYPC | 2995 | 202947_s_at | -0.7544 | 0.1929 | |
| GSE20347 | GYPC | 2995 | 202947_s_at | -0.7833 | 0.0000 | |
| GSE23400 | GYPC | 2995 | 202947_s_at | -0.3513 | 0.0000 | |
| GSE26886 | GYPC | 2995 | 202947_s_at | -0.1919 | 0.2762 | |
| GSE29001 | GYPC | 2995 | 202947_s_at | -0.3966 | 0.0130 | |
| GSE38129 | GYPC | 2995 | 202947_s_at | -1.1496 | 0.0001 | |
| GSE45670 | GYPC | 2995 | 202947_s_at | -1.1497 | 0.0000 | |
| GSE53622 | GYPC | 2995 | 148794 | -1.1715 | 0.0000 | |
| GSE53624 | GYPC | 2995 | 148794 | -0.9794 | 0.0000 | |
| GSE63941 | GYPC | 2995 | 202947_s_at | -2.3432 | 0.0000 | |
| GSE77861 | GYPC | 2995 | 202947_s_at | -0.3424 | 0.0026 | |
| GSE97050 | GYPC | 2995 | A_24_P139901 | -0.4932 | 0.1643 | |
| SRP007169 | GYPC | 2995 | RNAseq | 0.2798 | 0.6478 | |
| SRP008496 | GYPC | 2995 | RNAseq | 0.5133 | 0.2309 | |
| SRP064894 | GYPC | 2995 | RNAseq | -0.5098 | 0.1883 | |
| SRP133303 | GYPC | 2995 | RNAseq | -0.8443 | 0.0100 | |
| SRP159526 | GYPC | 2995 | RNAseq | -0.3905 | 0.1911 | |
| SRP193095 | GYPC | 2995 | RNAseq | -0.7704 | 0.0011 | |
| SRP219564 | GYPC | 2995 | RNAseq | -0.5605 | 0.5097 | |
| TCGA | GYPC | 2995 | RNAseq | -0.5192 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by GYPC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GYPC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GYPC | 2995 | 3 | 4 | 23 | |
| GSE20123 | GYPC | 2995 | 3 | 4 | 23 | |
| GSE43470 | GYPC | 2995 | 2 | 1 | 40 | |
| GSE46452 | GYPC | 2995 | 1 | 3 | 55 | |
| GSE47630 | GYPC | 2995 | 6 | 0 | 34 | |
| GSE54993 | GYPC | 2995 | 0 | 6 | 64 | |
| GSE54994 | GYPC | 2995 | 11 | 0 | 42 | |
| GSE60625 | GYPC | 2995 | 0 | 3 | 8 | |
| GSE74703 | GYPC | 2995 | 2 | 1 | 33 | |
| GSE74704 | GYPC | 2995 | 2 | 2 | 16 | |
| TCGA | GYPC | 2995 | 23 | 8 | 65 |
Total number of gains: 53; Total number of losses: 32; Total Number of normals: 403.
Somatic mutations of GYPC:
Generating mutation plots.
Highly correlated genes for GYPC:
Showing top 20/1520 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GYPC | MAGI2-AS3 | 0.83981 | 5 | 0 | 5 |
| GYPC | KCNT2 | 0.834379 | 6 | 0 | 6 |
| GYPC | C11orf96 | 0.820529 | 4 | 0 | 4 |
| GYPC | CYP4V2 | 0.82023 | 4 | 0 | 4 |
| GYPC | ABCA9 | 0.814814 | 3 | 0 | 3 |
| GYPC | ANGPTL1 | 0.812788 | 6 | 0 | 6 |
| GYPC | INMT | 0.80683 | 6 | 0 | 6 |
| GYPC | LINC01082 | 0.797216 | 5 | 0 | 5 |
| GYPC | CLEC3B | 0.795476 | 3 | 0 | 3 |
| GYPC | MRVI1 | 0.78996 | 7 | 0 | 6 |
| GYPC | CNTN3 | 0.787771 | 3 | 0 | 3 |
| GYPC | PNMA2 | 0.785036 | 3 | 0 | 3 |
| GYPC | DOK6 | 0.782199 | 4 | 0 | 4 |
| GYPC | DNAJB9 | 0.782023 | 3 | 0 | 3 |
| GYPC | FIBIN | 0.779027 | 6 | 0 | 5 |
| GYPC | ABCA8 | 0.775181 | 10 | 0 | 9 |
| GYPC | FAM13C | 0.77191 | 6 | 0 | 6 |
| GYPC | RAI2 | 0.771395 | 7 | 0 | 7 |
| GYPC | ADAMTS9-AS2 | 0.77105 | 5 | 0 | 5 |
| GYPC | WTIP | 0.771024 | 3 | 0 | 3 |
For details and further investigation, click here
