| Full name: Rho GTPase activating protein 39 | Alias Symbol: KIAA1688|Vilse|CrGAP | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 80728 | HGNC ID: HGNC:29351 | Ensembl Gene: ENSG00000147799 | OMIM ID: 615880 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP39:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP39 | 80728 | 227876_at | 0.8580 | 0.1767 | |
| GSE26886 | ARHGAP39 | 80728 | 227876_at | 0.3703 | 0.0480 | |
| GSE45670 | ARHGAP39 | 80728 | 227876_at | 0.0675 | 0.6550 | |
| GSE53622 | ARHGAP39 | 80728 | 97181 | 0.0234 | 0.8464 | |
| GSE53624 | ARHGAP39 | 80728 | 97181 | -0.1225 | 0.2921 | |
| GSE63941 | ARHGAP39 | 80728 | 227876_at | 0.7558 | 0.0070 | |
| GSE77861 | ARHGAP39 | 80728 | 227876_at | 0.0269 | 0.7814 | |
| GSE97050 | ARHGAP39 | 80728 | A_23_P424878 | 0.1258 | 0.5712 | |
| SRP007169 | ARHGAP39 | 80728 | RNAseq | -0.5797 | 0.3437 | |
| SRP064894 | ARHGAP39 | 80728 | RNAseq | 0.5906 | 0.0690 | |
| SRP133303 | ARHGAP39 | 80728 | RNAseq | 0.1713 | 0.4991 | |
| SRP159526 | ARHGAP39 | 80728 | RNAseq | 1.0576 | 0.0096 | |
| SRP193095 | ARHGAP39 | 80728 | RNAseq | 0.4100 | 0.0334 | |
| TCGA | ARHGAP39 | 80728 | RNAseq | 0.4058 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ARHGAP39 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP39:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP39 | 80728 | 18 | 1 | 11 | |
| GSE20123 | ARHGAP39 | 80728 | 18 | 1 | 11 | |
| GSE43470 | ARHGAP39 | 80728 | 16 | 2 | 25 | |
| GSE46452 | ARHGAP39 | 80728 | 28 | 0 | 31 | |
| GSE47630 | ARHGAP39 | 80728 | 25 | 1 | 14 | |
| GSE54993 | ARHGAP39 | 80728 | 0 | 25 | 45 | |
| GSE54994 | ARHGAP39 | 80728 | 39 | 1 | 13 | |
| GSE60625 | ARHGAP39 | 80728 | 3 | 4 | 4 | |
| GSE74703 | ARHGAP39 | 80728 | 14 | 1 | 21 | |
| GSE74704 | ARHGAP39 | 80728 | 11 | 0 | 9 | |
| TCGA | ARHGAP39 | 80728 | 63 | 2 | 31 |
Total number of gains: 235; Total number of losses: 38; Total Number of normals: 215.
Somatic mutations of ARHGAP39:
Generating mutation plots.
Highly correlated genes for ARHGAP39:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP39 | TYW5 | 0.81039 | 3 | 0 | 3 |
| ARHGAP39 | CHD7 | 0.773047 | 3 | 0 | 3 |
| ARHGAP39 | TMEM63B | 0.750304 | 3 | 0 | 3 |
| ARHGAP39 | FNBP1L | 0.745998 | 3 | 0 | 3 |
| ARHGAP39 | YWHAE | 0.739502 | 3 | 0 | 3 |
| ARHGAP39 | C9orf116 | 0.73389 | 3 | 0 | 3 |
| ARHGAP39 | FANCL | 0.730542 | 3 | 0 | 3 |
| ARHGAP39 | MTFR1 | 0.72887 | 3 | 0 | 3 |
| ARHGAP39 | NCOA6 | 0.726474 | 3 | 0 | 3 |
| ARHGAP39 | FLVCR1 | 0.726434 | 3 | 0 | 3 |
| ARHGAP39 | ANKRD27 | 0.726339 | 3 | 0 | 3 |
| ARHGAP39 | POLR1B | 0.720074 | 3 | 0 | 3 |
| ARHGAP39 | SF3B4 | 0.717438 | 3 | 0 | 3 |
| ARHGAP39 | MSTO1 | 0.716122 | 3 | 0 | 3 |
| ARHGAP39 | SFMBT1 | 0.713882 | 3 | 0 | 3 |
| ARHGAP39 | NOP14 | 0.709217 | 3 | 0 | 3 |
| ARHGAP39 | SAMD1 | 0.705556 | 3 | 0 | 3 |
| ARHGAP39 | COL11A2 | 0.703234 | 3 | 0 | 3 |
| ARHGAP39 | LARP1 | 0.701335 | 3 | 0 | 3 |
| ARHGAP39 | GSK3A | 0.699151 | 3 | 0 | 3 |
For details and further investigation, click here
