| Full name: carboxypeptidase A5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 93979 | HGNC ID: HGNC:15722 | Ensembl Gene: ENSG00000158525 | OMIM ID: 609561 |
| Drug and gene relationship at DGIdb | |||
Expression of CPA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPA5 | 93979 | 240744_at | -0.0769 | 0.7379 | |
| GSE26886 | CPA5 | 93979 | 240744_at | -0.1303 | 0.2341 | |
| GSE45670 | CPA5 | 93979 | 240744_at | 0.0428 | 0.6702 | |
| GSE53622 | CPA5 | 93979 | 45823 | -0.0035 | 0.9762 | |
| GSE53624 | CPA5 | 93979 | 45823 | -0.0336 | 0.7043 | |
| GSE63941 | CPA5 | 93979 | 240744_at | 0.2797 | 0.2709 | |
| GSE77861 | CPA5 | 93979 | 240744_at | -0.1509 | 0.1767 | |
| GSE97050 | CPA5 | 93979 | A_33_P3228600 | 0.1777 | 0.4651 | |
| TCGA | CPA5 | 93979 | RNAseq | 2.2637 | 0.0312 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CPA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPA5 | 93979 | 8 | 1 | 21 | |
| GSE20123 | CPA5 | 93979 | 8 | 1 | 21 | |
| GSE43470 | CPA5 | 93979 | 2 | 3 | 38 | |
| GSE46452 | CPA5 | 93979 | 7 | 2 | 50 | |
| GSE47630 | CPA5 | 93979 | 7 | 4 | 29 | |
| GSE54993 | CPA5 | 93979 | 3 | 5 | 62 | |
| GSE54994 | CPA5 | 93979 | 7 | 7 | 39 | |
| GSE60625 | CPA5 | 93979 | 0 | 0 | 11 | |
| GSE74703 | CPA5 | 93979 | 2 | 3 | 31 | |
| GSE74704 | CPA5 | 93979 | 4 | 1 | 15 | |
| TCGA | CPA5 | 93979 | 28 | 21 | 47 |
Total number of gains: 76; Total number of losses: 48; Total Number of normals: 364.
Somatic mutations of CPA5:
Generating mutation plots.
Highly correlated genes for CPA5:
Showing top 20/100 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPA5 | GALT | 0.757073 | 3 | 0 | 3 |
| CPA5 | SCN2B | 0.749472 | 3 | 0 | 3 |
| CPA5 | SNTG2 | 0.746526 | 3 | 0 | 3 |
| CPA5 | CATSPER3 | 0.733946 | 3 | 0 | 3 |
| CPA5 | KLK2 | 0.722921 | 3 | 0 | 3 |
| CPA5 | DYRK1B | 0.72246 | 3 | 0 | 3 |
| CPA5 | SPTBN5 | 0.713322 | 3 | 0 | 3 |
| CPA5 | CCDC62 | 0.708894 | 3 | 0 | 3 |
| CPA5 | PKD2L1 | 0.707441 | 3 | 0 | 3 |
| CPA5 | MYBPH | 0.707098 | 4 | 0 | 4 |
| CPA5 | CSHL1 | 0.701765 | 3 | 0 | 3 |
| CPA5 | GPT | 0.701557 | 3 | 0 | 3 |
| CPA5 | LELP1 | 0.695317 | 3 | 0 | 3 |
| CPA5 | ACAD10 | 0.693566 | 3 | 0 | 3 |
| CPA5 | SIGLEC8 | 0.693523 | 3 | 0 | 3 |
| CPA5 | FAM151A | 0.687545 | 3 | 0 | 3 |
| CPA5 | ICOSLG | 0.68475 | 4 | 0 | 4 |
| CPA5 | TBKBP1 | 0.683939 | 3 | 0 | 3 |
| CPA5 | HOXD9 | 0.681623 | 3 | 0 | 3 |
| CPA5 | NKX2-8 | 0.675011 | 3 | 0 | 3 |
For details and further investigation, click here
