| Full name: syntrophin gamma 2 | Alias Symbol: SYN5|G2SYN | ||
| Type: protein-coding gene | Cytoband: 2p25.3 | ||
| Entrez ID: 54221 | HGNC ID: HGNC:13741 | Ensembl Gene: ENSG00000172554 | OMIM ID: 608715 |
| Drug and gene relationship at DGIdb | |||
Expression of SNTG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNTG2 | 54221 | 1570422_at | -0.2775 | 0.1219 | |
| GSE20347 | SNTG2 | 54221 | 220487_at | 0.0159 | 0.7921 | |
| GSE23400 | SNTG2 | 54221 | 220487_at | -0.0474 | 0.0248 | |
| GSE26886 | SNTG2 | 54221 | 220487_at | 0.2889 | 0.0142 | |
| GSE29001 | SNTG2 | 54221 | 220487_at | 0.0887 | 0.6744 | |
| GSE38129 | SNTG2 | 54221 | 220487_at | -0.1041 | 0.0932 | |
| GSE45670 | SNTG2 | 54221 | 220487_at | -0.3274 | 0.0067 | |
| GSE53622 | SNTG2 | 54221 | 33678 | -0.8448 | 0.0000 | |
| GSE53624 | SNTG2 | 54221 | 33678 | -1.1799 | 0.0000 | |
| GSE63941 | SNTG2 | 54221 | 220487_at | 0.1086 | 0.3844 | |
| GSE77861 | SNTG2 | 54221 | 220487_at | -0.0819 | 0.5490 | |
| GSE97050 | SNTG2 | 54221 | A_23_P251132 | 0.2385 | 0.5673 | |
| SRP133303 | SNTG2 | 54221 | RNAseq | -2.2271 | 0.0000 | |
| SRP219564 | SNTG2 | 54221 | RNAseq | 1.3650 | 0.1836 | |
| TCGA | SNTG2 | 54221 | RNAseq | -2.2620 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SNTG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNTG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNTG2 | 54221 | 8 | 2 | 20 | |
| GSE20123 | SNTG2 | 54221 | 8 | 2 | 20 | |
| GSE43470 | SNTG2 | 54221 | 3 | 1 | 39 | |
| GSE46452 | SNTG2 | 54221 | 3 | 4 | 52 | |
| GSE47630 | SNTG2 | 54221 | 7 | 0 | 33 | |
| GSE54993 | SNTG2 | 54221 | 1 | 7 | 62 | |
| GSE54994 | SNTG2 | 54221 | 13 | 0 | 40 | |
| GSE60625 | SNTG2 | 54221 | 0 | 3 | 8 | |
| GSE74703 | SNTG2 | 54221 | 3 | 0 | 33 | |
| GSE74704 | SNTG2 | 54221 | 8 | 1 | 11 | |
| TCGA | SNTG2 | 54221 | 32 | 5 | 59 |
Total number of gains: 86; Total number of losses: 25; Total Number of normals: 377.
Somatic mutations of SNTG2:
Generating mutation plots.
Highly correlated genes for SNTG2:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNTG2 | NOXA1 | 0.759435 | 3 | 0 | 3 |
| SNTG2 | CPA5 | 0.746526 | 3 | 0 | 3 |
| SNTG2 | KCNA7 | 0.726635 | 3 | 0 | 3 |
| SNTG2 | LRFN2 | 0.724965 | 3 | 0 | 3 |
| SNTG2 | ZMYND10 | 0.71416 | 3 | 0 | 3 |
| SNTG2 | ADD2 | 0.704101 | 3 | 0 | 3 |
| SNTG2 | CNTN4 | 0.702989 | 3 | 0 | 3 |
| SNTG2 | THEG | 0.699033 | 4 | 0 | 4 |
| SNTG2 | FXYD2 | 0.693232 | 3 | 0 | 3 |
| SNTG2 | SLC30A2 | 0.691878 | 4 | 0 | 3 |
| SNTG2 | LENG1 | 0.684999 | 3 | 0 | 3 |
| SNTG2 | TDRD9 | 0.679695 | 3 | 0 | 3 |
| SNTG2 | LELP1 | 0.678531 | 3 | 0 | 3 |
| SNTG2 | SLC4A9 | 0.677507 | 3 | 0 | 3 |
| SNTG2 | MGAT5B | 0.675062 | 3 | 0 | 3 |
| SNTG2 | ITGA2B | 0.671155 | 5 | 0 | 4 |
| SNTG2 | VWA5B2 | 0.667233 | 3 | 0 | 3 |
| SNTG2 | HNF1B | 0.666775 | 4 | 0 | 4 |
| SNTG2 | THRSP | 0.665833 | 3 | 0 | 3 |
| SNTG2 | TMEM63A | 0.66527 | 3 | 0 | 3 |
For details and further investigation, click here
