| Full name: pre-mRNA processing factor 31 | Alias Symbol: NY-BR-99|PRP31|hPrp31|SNRNP61 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 26121 | HGNC ID: HGNC:15446 | Ensembl Gene: ENSG00000105618 | OMIM ID: 606419 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPF31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPF31 | 26121 | 202408_s_at | 0.5238 | 0.2418 | |
| GSE20347 | PRPF31 | 26121 | 202408_s_at | 0.2878 | 0.0460 | |
| GSE23400 | PRPF31 | 26121 | 202408_s_at | 0.3865 | 0.0000 | |
| GSE26886 | PRPF31 | 26121 | 202408_s_at | 0.5375 | 0.0045 | |
| GSE29001 | PRPF31 | 26121 | 202408_s_at | 0.1744 | 0.6236 | |
| GSE38129 | PRPF31 | 26121 | 202408_s_at | 0.3888 | 0.0008 | |
| GSE45670 | PRPF31 | 26121 | 202408_s_at | 0.2452 | 0.0404 | |
| GSE53622 | PRPF31 | 26121 | 3007 | 0.2142 | 0.0003 | |
| GSE53624 | PRPF31 | 26121 | 3007 | 0.3728 | 0.0000 | |
| GSE63941 | PRPF31 | 26121 | 202408_s_at | -0.1397 | 0.6733 | |
| GSE77861 | PRPF31 | 26121 | 202408_s_at | 0.3206 | 0.1038 | |
| GSE97050 | PRPF31 | 26121 | A_33_P3369039 | 0.1351 | 0.4948 | |
| SRP007169 | PRPF31 | 26121 | RNAseq | 0.6889 | 0.0892 | |
| SRP008496 | PRPF31 | 26121 | RNAseq | 0.5463 | 0.0397 | |
| SRP064894 | PRPF31 | 26121 | RNAseq | 0.7972 | 0.0046 | |
| SRP133303 | PRPF31 | 26121 | RNAseq | 0.4831 | 0.0110 | |
| SRP159526 | PRPF31 | 26121 | RNAseq | 0.5163 | 0.0789 | |
| SRP193095 | PRPF31 | 26121 | RNAseq | 0.4006 | 0.0001 | |
| SRP219564 | PRPF31 | 26121 | RNAseq | 0.0558 | 0.8390 | |
| TCGA | PRPF31 | 26121 | RNAseq | 0.1138 | 0.0226 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRPF31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPF31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPF31 | 26121 | 3 | 4 | 23 | |
| GSE20123 | PRPF31 | 26121 | 3 | 3 | 24 | |
| GSE43470 | PRPF31 | 26121 | 2 | 11 | 30 | |
| GSE46452 | PRPF31 | 26121 | 45 | 1 | 13 | |
| GSE47630 | PRPF31 | 26121 | 8 | 6 | 26 | |
| GSE54993 | PRPF31 | 26121 | 17 | 4 | 49 | |
| GSE54994 | PRPF31 | 26121 | 4 | 14 | 35 | |
| GSE60625 | PRPF31 | 26121 | 9 | 0 | 2 | |
| GSE74703 | PRPF31 | 26121 | 2 | 7 | 27 | |
| GSE74704 | PRPF31 | 26121 | 3 | 1 | 16 | |
| TCGA | PRPF31 | 26121 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 66; Total Number of normals: 307.
Somatic mutations of PRPF31:
Generating mutation plots.
Highly correlated genes for PRPF31:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPF31 | MBD6 | 0.839676 | 3 | 0 | 3 |
| PRPF31 | CPAMD8 | 0.78537 | 3 | 0 | 3 |
| PRPF31 | ABHD11 | 0.774516 | 3 | 0 | 3 |
| PRPF31 | TFB1M | 0.762292 | 3 | 0 | 3 |
| PRPF31 | MAK | 0.744239 | 3 | 0 | 3 |
| PRPF31 | TIGD5 | 0.737036 | 3 | 0 | 3 |
| PRPF31 | CHGB | 0.726189 | 3 | 0 | 3 |
| PRPF31 | NTNG2 | 0.722784 | 3 | 0 | 3 |
| PRPF31 | PRR18 | 0.712731 | 3 | 0 | 3 |
| PRPF31 | FAM24B | 0.702358 | 4 | 0 | 3 |
| PRPF31 | ZNF283 | 0.69007 | 4 | 0 | 3 |
| PRPF31 | C19orf12 | 0.686696 | 3 | 0 | 3 |
| PRPF31 | DOHH | 0.682258 | 5 | 0 | 4 |
| PRPF31 | GTF2IRD2 | 0.680646 | 4 | 0 | 3 |
| PRPF31 | WDR83 | 0.676249 | 5 | 0 | 5 |
| PRPF31 | TMEM120B | 0.673975 | 4 | 0 | 3 |
| PRPF31 | ALDH16A1 | 0.667355 | 7 | 0 | 7 |
| PRPF31 | ZMYND15 | 0.66715 | 4 | 0 | 3 |
| PRPF31 | RHPN2 | 0.662971 | 5 | 0 | 4 |
| PRPF31 | PRR15 | 0.657223 | 3 | 0 | 3 |
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