| Full name: copine 2 | Alias Symbol: CPN2 | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 221184 | HGNC ID: HGNC:2315 | Ensembl Gene: ENSG00000140848 | OMIM ID: 604206 |
| Drug and gene relationship at DGIdb | |||
Expression of CPNE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPNE2 | 221184 | 225129_at | 0.6072 | 0.0510 | |
| GSE26886 | CPNE2 | 221184 | 225129_at | 0.9427 | 0.0001 | |
| GSE45670 | CPNE2 | 221184 | 225129_at | 0.1409 | 0.5037 | |
| GSE53622 | CPNE2 | 221184 | 1315 | 0.7137 | 0.0000 | |
| GSE53624 | CPNE2 | 221184 | 1315 | 0.6143 | 0.0000 | |
| GSE63941 | CPNE2 | 221184 | 225129_at | 1.8979 | 0.0011 | |
| GSE77861 | CPNE2 | 221184 | 225129_at | 0.6793 | 0.0721 | |
| GSE97050 | CPNE2 | 221184 | A_23_P37988 | 0.3754 | 0.1450 | |
| SRP007169 | CPNE2 | 221184 | RNAseq | 0.8270 | 0.0721 | |
| SRP008496 | CPNE2 | 221184 | RNAseq | 0.8114 | 0.0173 | |
| SRP064894 | CPNE2 | 221184 | RNAseq | 0.7306 | 0.0001 | |
| SRP133303 | CPNE2 | 221184 | RNAseq | 0.5440 | 0.0034 | |
| SRP159526 | CPNE2 | 221184 | RNAseq | 0.4617 | 0.0714 | |
| SRP193095 | CPNE2 | 221184 | RNAseq | 0.8833 | 0.0000 | |
| SRP219564 | CPNE2 | 221184 | RNAseq | 0.7521 | 0.0446 | |
| TCGA | CPNE2 | 221184 | RNAseq | 0.4296 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CPNE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPNE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPNE2 | 221184 | 6 | 0 | 24 | |
| GSE20123 | CPNE2 | 221184 | 6 | 1 | 23 | |
| GSE43470 | CPNE2 | 221184 | 3 | 6 | 34 | |
| GSE46452 | CPNE2 | 221184 | 38 | 1 | 20 | |
| GSE47630 | CPNE2 | 221184 | 10 | 8 | 22 | |
| GSE54993 | CPNE2 | 221184 | 2 | 4 | 64 | |
| GSE54994 | CPNE2 | 221184 | 7 | 10 | 36 | |
| GSE60625 | CPNE2 | 221184 | 4 | 0 | 7 | |
| GSE74703 | CPNE2 | 221184 | 3 | 3 | 30 | |
| GSE74704 | CPNE2 | 221184 | 5 | 0 | 15 | |
| TCGA | CPNE2 | 221184 | 25 | 13 | 58 |
Total number of gains: 109; Total number of losses: 46; Total Number of normals: 333.
Somatic mutations of CPNE2:
Generating mutation plots.
Highly correlated genes for CPNE2:
Showing top 20/1372 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPNE2 | HYOU1 | 0.821585 | 3 | 0 | 3 |
| CPNE2 | KRTCAP2 | 0.815676 | 3 | 0 | 3 |
| CPNE2 | LTBR | 0.812255 | 3 | 0 | 3 |
| CPNE2 | ZNF384 | 0.794238 | 4 | 0 | 4 |
| CPNE2 | SLC38A10 | 0.769781 | 4 | 0 | 4 |
| CPNE2 | SLC25A37 | 0.768878 | 3 | 0 | 3 |
| CPNE2 | SOX13 | 0.763721 | 3 | 0 | 3 |
| CPNE2 | ZNF628 | 0.756261 | 3 | 0 | 3 |
| CPNE2 | RFX1 | 0.753581 | 3 | 0 | 3 |
| CPNE2 | C9orf16 | 0.75254 | 3 | 0 | 3 |
| CPNE2 | CELSR2 | 0.747834 | 3 | 0 | 3 |
| CPNE2 | IDS | 0.744762 | 3 | 0 | 3 |
| CPNE2 | KCTD13 | 0.743357 | 3 | 0 | 3 |
| CPNE2 | C1orf115 | 0.741983 | 3 | 0 | 3 |
| CPNE2 | CCT5 | 0.738139 | 4 | 0 | 4 |
| CPNE2 | CCDC86 | 0.731714 | 4 | 0 | 4 |
| CPNE2 | RPAIN | 0.730144 | 3 | 0 | 3 |
| CPNE2 | SOCS7 | 0.729515 | 3 | 0 | 3 |
| CPNE2 | DDX11 | 0.72688 | 5 | 0 | 4 |
| CPNE2 | PYCR2 | 0.726285 | 3 | 0 | 3 |
For details and further investigation, click here
