| Full name: regulatory factor X1 | Alias Symbol: EF-C | ||
| Type: protein-coding gene | Cytoband: 19p13.12 | ||
| Entrez ID: 5989 | HGNC ID: HGNC:9982 | Ensembl Gene: ENSG00000132005 | OMIM ID: 600006 |
| Drug and gene relationship at DGIdb | |||
Expression of RFX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFX1 | 5989 | 226786_at | 0.1915 | 0.6504 | |
| GSE20347 | RFX1 | 5989 | 206321_at | -0.1320 | 0.0065 | |
| GSE23400 | RFX1 | 5989 | 206321_at | -0.1161 | 0.0000 | |
| GSE26886 | RFX1 | 5989 | 226786_at | 0.3982 | 0.0057 | |
| GSE29001 | RFX1 | 5989 | 206321_at | -0.1376 | 0.1608 | |
| GSE38129 | RFX1 | 5989 | 206321_at | -0.1225 | 0.0175 | |
| GSE45670 | RFX1 | 5989 | 226786_at | 0.0975 | 0.2112 | |
| GSE63941 | RFX1 | 5989 | 226786_at | 0.3703 | 0.1340 | |
| GSE77861 | RFX1 | 5989 | 226786_at | 0.2514 | 0.1360 | |
| GSE97050 | RFX1 | 5989 | A_24_P391104 | 0.2340 | 0.3612 | |
| SRP007169 | RFX1 | 5989 | RNAseq | 0.0151 | 0.9766 | |
| SRP064894 | RFX1 | 5989 | RNAseq | 0.0942 | 0.6235 | |
| SRP133303 | RFX1 | 5989 | RNAseq | -0.3795 | 0.0172 | |
| SRP159526 | RFX1 | 5989 | RNAseq | 0.0620 | 0.8339 | |
| SRP193095 | RFX1 | 5989 | RNAseq | -0.0065 | 0.9689 | |
| SRP219564 | RFX1 | 5989 | RNAseq | 0.3300 | 0.3436 | |
| TCGA | RFX1 | 5989 | RNAseq | -0.0783 | 0.1150 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFX1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RFX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFX1 | 5989 | 4 | 2 | 24 | |
| GSE20123 | RFX1 | 5989 | 3 | 1 | 26 | |
| GSE43470 | RFX1 | 5989 | 2 | 6 | 35 | |
| GSE46452 | RFX1 | 5989 | 47 | 1 | 11 | |
| GSE47630 | RFX1 | 5989 | 4 | 7 | 29 | |
| GSE54993 | RFX1 | 5989 | 15 | 4 | 51 | |
| GSE54994 | RFX1 | 5989 | 6 | 13 | 34 | |
| GSE60625 | RFX1 | 5989 | 9 | 0 | 2 | |
| GSE74703 | RFX1 | 5989 | 2 | 4 | 30 | |
| GSE74704 | RFX1 | 5989 | 0 | 1 | 19 | |
| TCGA | RFX1 | 5989 | 22 | 11 | 63 |
Total number of gains: 114; Total number of losses: 50; Total Number of normals: 324.
Somatic mutations of RFX1:
Generating mutation plots.
Highly correlated genes for RFX1:
Showing top 20/373 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFX1 | TMEM86B | 0.77993 | 3 | 0 | 3 |
| RFX1 | ATAT1 | 0.765703 | 3 | 0 | 3 |
| RFX1 | AARS2 | 0.763463 | 3 | 0 | 3 |
| RFX1 | RSAD1 | 0.762398 | 3 | 0 | 3 |
| RFX1 | AAK1 | 0.762046 | 3 | 0 | 3 |
| RFX1 | PIAS3 | 0.759907 | 3 | 0 | 3 |
| RFX1 | LSM14B | 0.757661 | 3 | 0 | 3 |
| RFX1 | NRM | 0.757432 | 3 | 0 | 3 |
| RFX1 | TRIM8 | 0.755825 | 3 | 0 | 3 |
| RFX1 | SLC9A1 | 0.755249 | 3 | 0 | 3 |
| RFX1 | CPNE2 | 0.753581 | 3 | 0 | 3 |
| RFX1 | GAS2L1 | 0.74221 | 3 | 0 | 3 |
| RFX1 | TRIM47 | 0.740975 | 3 | 0 | 3 |
| RFX1 | GOLGA8A | 0.740806 | 3 | 0 | 3 |
| RFX1 | PDCD2L | 0.737425 | 3 | 0 | 3 |
| RFX1 | TMTC4 | 0.733465 | 3 | 0 | 3 |
| RFX1 | RNF26 | 0.728511 | 3 | 0 | 3 |
| RFX1 | DNTTIP1 | 0.726462 | 3 | 0 | 3 |
| RFX1 | AKT1S1 | 0.717227 | 3 | 0 | 3 |
| RFX1 | PRR13 | 0.715544 | 3 | 0 | 3 |
For details and further investigation, click here
