| Full name: hypoxia up-regulated 1 | Alias Symbol: ORP150|HSP12A|Grp170 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 10525 | HGNC ID: HGNC:16931 | Ensembl Gene: ENSG00000149428 | OMIM ID: 601746 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HYOU1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HYOU1 | 10525 | 200825_s_at | 0.8620 | 0.0657 | |
| GSE20347 | HYOU1 | 10525 | 200825_s_at | -0.0166 | 0.9253 | |
| GSE23400 | HYOU1 | 10525 | 200825_s_at | 0.2847 | 0.0004 | |
| GSE26886 | HYOU1 | 10525 | 200825_s_at | -0.4317 | 0.1109 | |
| GSE29001 | HYOU1 | 10525 | 200825_s_at | -0.4324 | 0.1565 | |
| GSE38129 | HYOU1 | 10525 | 200825_s_at | 0.2426 | 0.0980 | |
| GSE45670 | HYOU1 | 10525 | 200825_s_at | 0.4549 | 0.0050 | |
| GSE53622 | HYOU1 | 10525 | 106250 | 0.5539 | 0.0000 | |
| GSE53624 | HYOU1 | 10525 | 106250 | 0.6506 | 0.0000 | |
| GSE63941 | HYOU1 | 10525 | 200825_s_at | 0.3454 | 0.5765 | |
| GSE77861 | HYOU1 | 10525 | 200825_s_at | 0.1746 | 0.5261 | |
| GSE97050 | HYOU1 | 10525 | A_23_P75647 | 0.7719 | 0.1780 | |
| SRP007169 | HYOU1 | 10525 | RNAseq | 0.0948 | 0.8426 | |
| SRP008496 | HYOU1 | 10525 | RNAseq | 0.3686 | 0.1604 | |
| SRP064894 | HYOU1 | 10525 | RNAseq | 0.5641 | 0.0013 | |
| SRP133303 | HYOU1 | 10525 | RNAseq | 0.5639 | 0.0096 | |
| SRP159526 | HYOU1 | 10525 | RNAseq | 0.8853 | 0.0140 | |
| SRP193095 | HYOU1 | 10525 | RNAseq | 0.3070 | 0.0841 | |
| SRP219564 | HYOU1 | 10525 | RNAseq | 0.6256 | 0.0657 | |
| TCGA | HYOU1 | 10525 | RNAseq | -0.0943 | 0.0375 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HYOU1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HYOU1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HYOU1 | 10525 | 1 | 11 | 18 | |
| GSE20123 | HYOU1 | 10525 | 1 | 11 | 18 | |
| GSE43470 | HYOU1 | 10525 | 2 | 8 | 33 | |
| GSE46452 | HYOU1 | 10525 | 3 | 26 | 30 | |
| GSE47630 | HYOU1 | 10525 | 2 | 19 | 19 | |
| GSE54993 | HYOU1 | 10525 | 10 | 0 | 60 | |
| GSE54994 | HYOU1 | 10525 | 5 | 19 | 29 | |
| GSE60625 | HYOU1 | 10525 | 0 | 3 | 8 | |
| GSE74703 | HYOU1 | 10525 | 1 | 5 | 30 | |
| GSE74704 | HYOU1 | 10525 | 0 | 7 | 13 | |
| TCGA | HYOU1 | 10525 | 4 | 51 | 41 |
Total number of gains: 29; Total number of losses: 160; Total Number of normals: 299.
Somatic mutations of HYOU1:
Generating mutation plots.
Highly correlated genes for HYOU1:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HYOU1 | CPNE2 | 0.821585 | 3 | 0 | 3 |
| HYOU1 | GORAB | 0.783416 | 3 | 0 | 3 |
| HYOU1 | ZBTB39 | 0.773703 | 3 | 0 | 3 |
| HYOU1 | TNFAIP1 | 0.759111 | 3 | 0 | 3 |
| HYOU1 | SLC39A3 | 0.758044 | 3 | 0 | 3 |
| HYOU1 | SGSH | 0.754188 | 3 | 0 | 3 |
| HYOU1 | UCK2 | 0.729753 | 3 | 0 | 3 |
| HYOU1 | CAPN12 | 0.724044 | 3 | 0 | 3 |
| HYOU1 | CLCN7 | 0.721284 | 4 | 0 | 3 |
| HYOU1 | NACC1 | 0.721143 | 3 | 0 | 3 |
| HYOU1 | TFDP3 | 0.720073 | 3 | 0 | 3 |
| HYOU1 | UHMK1 | 0.7192 | 4 | 0 | 3 |
| HYOU1 | NENF | 0.711718 | 3 | 0 | 3 |
| HYOU1 | C2CD2L | 0.706608 | 4 | 0 | 4 |
| HYOU1 | UBR4 | 0.706437 | 5 | 0 | 5 |
| HYOU1 | SARS2 | 0.704191 | 4 | 0 | 3 |
| HYOU1 | RAB1B | 0.703433 | 4 | 0 | 4 |
| HYOU1 | TTC38 | 0.701338 | 3 | 0 | 3 |
| HYOU1 | MBD1 | 0.696193 | 3 | 0 | 3 |
| HYOU1 | FAM86C1 | 0.695637 | 3 | 0 | 3 |
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