| Full name: RPA interacting protein | Alias Symbol: MGC4189|RIP|hRIP | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 84268 | HGNC ID: HGNC:28641 | Ensembl Gene: ENSG00000129197 | OMIM ID: 617299 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPAIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPAIN | 84268 | 228183_s_at | -0.0208 | 0.9684 | |
| GSE20347 | RPAIN | 84268 | 216961_s_at | 0.0246 | 0.7345 | |
| GSE23400 | RPAIN | 84268 | 216961_s_at | 0.0271 | 0.3824 | |
| GSE26886 | RPAIN | 84268 | 228183_s_at | 0.8123 | 0.0000 | |
| GSE29001 | RPAIN | 84268 | 216962_at | 0.1114 | 0.6413 | |
| GSE38129 | RPAIN | 84268 | 216961_s_at | -0.0723 | 0.2955 | |
| GSE45670 | RPAIN | 84268 | 228183_s_at | -0.0276 | 0.9106 | |
| GSE53622 | RPAIN | 84268 | 34637 | 0.2197 | 0.0020 | |
| GSE53624 | RPAIN | 84268 | 34637 | 0.2072 | 0.0225 | |
| GSE63941 | RPAIN | 84268 | 228183_s_at | 0.3130 | 0.5553 | |
| GSE77861 | RPAIN | 84268 | 228183_s_at | 0.1949 | 0.3416 | |
| GSE97050 | RPAIN | 84268 | A_23_P66766 | 0.0212 | 0.9388 | |
| SRP007169 | RPAIN | 84268 | RNAseq | -0.0177 | 0.9681 | |
| SRP008496 | RPAIN | 84268 | RNAseq | -0.0551 | 0.8409 | |
| SRP064894 | RPAIN | 84268 | RNAseq | 0.0920 | 0.5315 | |
| SRP133303 | RPAIN | 84268 | RNAseq | -0.1674 | 0.3001 | |
| SRP159526 | RPAIN | 84268 | RNAseq | 0.5828 | 0.0040 | |
| SRP193095 | RPAIN | 84268 | RNAseq | -0.0666 | 0.5789 | |
| SRP219564 | RPAIN | 84268 | RNAseq | 0.1360 | 0.7232 | |
| TCGA | RPAIN | 84268 | RNAseq | -0.0170 | 0.8021 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPAIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPAIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPAIN | 84268 | 5 | 2 | 23 | |
| GSE20123 | RPAIN | 84268 | 5 | 3 | 22 | |
| GSE43470 | RPAIN | 84268 | 1 | 6 | 36 | |
| GSE46452 | RPAIN | 84268 | 34 | 1 | 24 | |
| GSE47630 | RPAIN | 84268 | 7 | 1 | 32 | |
| GSE54993 | RPAIN | 84268 | 4 | 3 | 63 | |
| GSE54994 | RPAIN | 84268 | 5 | 8 | 40 | |
| GSE60625 | RPAIN | 84268 | 4 | 0 | 7 | |
| GSE74703 | RPAIN | 84268 | 1 | 3 | 32 | |
| GSE74704 | RPAIN | 84268 | 3 | 1 | 16 | |
| TCGA | RPAIN | 84268 | 18 | 20 | 58 |
Total number of gains: 87; Total number of losses: 48; Total Number of normals: 353.
Somatic mutations of RPAIN:
Generating mutation plots.
Highly correlated genes for RPAIN:
Showing top 20/275 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPAIN | TPCN2 | 0.777591 | 3 | 0 | 3 |
| RPAIN | BOD1 | 0.761856 | 3 | 0 | 3 |
| RPAIN | METTL23 | 0.747845 | 3 | 0 | 3 |
| RPAIN | ANKFY1 | 0.744907 | 3 | 0 | 3 |
| RPAIN | NSUN5 | 0.739947 | 3 | 0 | 3 |
| RPAIN | ZNF721 | 0.737502 | 3 | 0 | 3 |
| RPAIN | ZFYVE27 | 0.732384 | 3 | 0 | 3 |
| RPAIN | CPNE2 | 0.730144 | 3 | 0 | 3 |
| RPAIN | XYLT2 | 0.72171 | 3 | 0 | 3 |
| RPAIN | THEM4 | 0.720321 | 3 | 0 | 3 |
| RPAIN | PLXNA1 | 0.715839 | 3 | 0 | 3 |
| RPAIN | METAP2 | 0.715184 | 3 | 0 | 3 |
| RPAIN | DZIP1L | 0.712588 | 4 | 0 | 3 |
| RPAIN | RPS27A | 0.71245 | 3 | 0 | 3 |
| RPAIN | C12orf43 | 0.711119 | 3 | 0 | 3 |
| RPAIN | ALKBH6 | 0.709946 | 4 | 0 | 4 |
| RPAIN | C2orf69 | 0.708254 | 3 | 0 | 3 |
| RPAIN | CBLB | 0.707543 | 3 | 0 | 3 |
| RPAIN | MZT2B | 0.706638 | 3 | 0 | 3 |
| RPAIN | DOCK11 | 0.70126 | 3 | 0 | 3 |
For details and further investigation, click here
