| Full name: cellular retinoic acid binding protein 2 | Alias Symbol: CRABP-II | ||
| Type: protein-coding gene | Cytoband: 1q23.1 | ||
| Entrez ID: 1382 | HGNC ID: HGNC:2339 | Ensembl Gene: ENSG00000143320 | OMIM ID: 180231 |
| Drug and gene relationship at DGIdb | |||
Expression of CRABP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRABP2 | 1382 | 202575_at | -2.1531 | 0.1508 | |
| GSE20347 | CRABP2 | 1382 | 202575_at | -3.1049 | 0.0000 | |
| GSE23400 | CRABP2 | 1382 | 202575_at | -2.3284 | 0.0000 | |
| GSE26886 | CRABP2 | 1382 | 202575_at | -3.4675 | 0.0000 | |
| GSE29001 | CRABP2 | 1382 | 202575_at | -2.4393 | 0.0000 | |
| GSE38129 | CRABP2 | 1382 | 202575_at | -1.8750 | 0.0015 | |
| GSE45670 | CRABP2 | 1382 | 202575_at | -0.8387 | 0.0085 | |
| GSE53622 | CRABP2 | 1382 | 117772 | -2.2189 | 0.0000 | |
| GSE53624 | CRABP2 | 1382 | 117772 | -2.4889 | 0.0000 | |
| GSE63941 | CRABP2 | 1382 | 202575_at | 1.2245 | 0.4085 | |
| GSE77861 | CRABP2 | 1382 | 202575_at | -2.0203 | 0.0024 | |
| GSE97050 | CRABP2 | 1382 | A_23_P115064 | -0.7709 | 0.2074 | |
| SRP007169 | CRABP2 | 1382 | RNAseq | -5.7587 | 0.0000 | |
| SRP008496 | CRABP2 | 1382 | RNAseq | -4.3825 | 0.0000 | |
| SRP064894 | CRABP2 | 1382 | RNAseq | -3.0351 | 0.0000 | |
| SRP133303 | CRABP2 | 1382 | RNAseq | -3.4567 | 0.0000 | |
| SRP159526 | CRABP2 | 1382 | RNAseq | -3.4656 | 0.0000 | |
| SRP219564 | CRABP2 | 1382 | RNAseq | -2.4973 | 0.0036 | |
| TCGA | CRABP2 | 1382 | RNAseq | 0.6518 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by CRABP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRABP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRABP2 | 1382 | 12 | 0 | 18 | |
| GSE20123 | CRABP2 | 1382 | 12 | 0 | 18 | |
| GSE43470 | CRABP2 | 1382 | 7 | 2 | 34 | |
| GSE46452 | CRABP2 | 1382 | 2 | 1 | 56 | |
| GSE47630 | CRABP2 | 1382 | 14 | 0 | 26 | |
| GSE54993 | CRABP2 | 1382 | 0 | 5 | 65 | |
| GSE54994 | CRABP2 | 1382 | 16 | 0 | 37 | |
| GSE60625 | CRABP2 | 1382 | 0 | 0 | 11 | |
| GSE74703 | CRABP2 | 1382 | 7 | 2 | 27 | |
| GSE74704 | CRABP2 | 1382 | 6 | 0 | 14 | |
| TCGA | CRABP2 | 1382 | 38 | 2 | 56 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of CRABP2:
Generating mutation plots.
Highly correlated genes for CRABP2:
Showing top 20/1400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRABP2 | VSIG10L | 0.865892 | 7 | 0 | 7 |
| CRABP2 | CYSRT1 | 0.833359 | 6 | 0 | 6 |
| CRABP2 | RHCG | 0.833162 | 12 | 0 | 12 |
| CRABP2 | SLC16A6 | 0.820193 | 10 | 0 | 10 |
| CRABP2 | CXCR2 | 0.818453 | 10 | 0 | 10 |
| CRABP2 | NCCRP1 | 0.818369 | 4 | 0 | 4 |
| CRABP2 | TMEM40 | 0.814898 | 11 | 0 | 11 |
| CRABP2 | IQCF1 | 0.811707 | 4 | 0 | 4 |
| CRABP2 | GRHL3 | 0.810408 | 6 | 0 | 6 |
| CRABP2 | KPRP | 0.810324 | 3 | 0 | 3 |
| CRABP2 | CWH43 | 0.804843 | 10 | 0 | 10 |
| CRABP2 | EPS8L2 | 0.804383 | 11 | 0 | 11 |
| CRABP2 | C5orf66-AS1 | 0.802259 | 5 | 0 | 5 |
| CRABP2 | MXD1 | 0.80219 | 11 | 0 | 11 |
| CRABP2 | EVPL | 0.801579 | 12 | 0 | 11 |
| CRABP2 | DHRS1 | 0.801472 | 12 | 0 | 11 |
| CRABP2 | CRCT1 | 0.799578 | 12 | 0 | 12 |
| CRABP2 | C3orf20 | 0.79736 | 4 | 0 | 4 |
| CRABP2 | CNFN | 0.796771 | 8 | 0 | 8 |
| CRABP2 | ECM1 | 0.795973 | 12 | 0 | 12 |
For details and further investigation, click here
