| Full name: solute carrier family 16 member 6 | Alias Symbol: MCT6|MCT7 | ||
| Type: protein-coding gene | Cytoband: 17q24.2 | ||
| Entrez ID: 9120 | HGNC ID: HGNC:10927 | Ensembl Gene: ENSG00000108932 | OMIM ID: 603880 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC16A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC16A6 | 9120 | 230748_at | -2.3836 | 0.0737 | |
| GSE20347 | SLC16A6 | 9120 | 207038_at | -2.4473 | 0.0000 | |
| GSE23400 | SLC16A6 | 9120 | 207038_at | -0.9062 | 0.0000 | |
| GSE26886 | SLC16A6 | 9120 | 230748_at | -4.8601 | 0.0000 | |
| GSE29001 | SLC16A6 | 9120 | 207038_at | -2.2223 | 0.0000 | |
| GSE38129 | SLC16A6 | 9120 | 207038_at | -1.8544 | 0.0000 | |
| GSE45670 | SLC16A6 | 9120 | 230748_at | -1.8463 | 0.0011 | |
| GSE53622 | SLC16A6 | 9120 | 43864 | -2.2698 | 0.0000 | |
| GSE53624 | SLC16A6 | 9120 | 43864 | -2.7968 | 0.0000 | |
| GSE63941 | SLC16A6 | 9120 | 230748_at | -1.0105 | 0.3047 | |
| GSE77861 | SLC16A6 | 9120 | 230748_at | -2.5759 | 0.0005 | |
| GSE97050 | SLC16A6 | 9120 | A_23_P152791 | -0.7521 | 0.1929 | |
| SRP007169 | SLC16A6 | 9120 | RNAseq | -4.2942 | 0.0000 | |
| SRP008496 | SLC16A6 | 9120 | RNAseq | -3.4753 | 0.0000 | |
| SRP064894 | SLC16A6 | 9120 | RNAseq | -2.3363 | 0.0000 | |
| SRP133303 | SLC16A6 | 9120 | RNAseq | -1.7134 | 0.0000 | |
| SRP159526 | SLC16A6 | 9120 | RNAseq | -2.7649 | 0.0000 | |
| SRP193095 | SLC16A6 | 9120 | RNAseq | -2.5016 | 0.0000 | |
| SRP219564 | SLC16A6 | 9120 | RNAseq | -2.1805 | 0.0074 | |
| TCGA | SLC16A6 | 9120 | RNAseq | 0.1683 | 0.5449 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by SLC16A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC16A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC16A6 | 9120 | 3 | 3 | 24 | |
| GSE20123 | SLC16A6 | 9120 | 3 | 3 | 24 | |
| GSE43470 | SLC16A6 | 9120 | 4 | 0 | 39 | |
| GSE46452 | SLC16A6 | 9120 | 31 | 1 | 27 | |
| GSE47630 | SLC16A6 | 9120 | 7 | 1 | 32 | |
| GSE54993 | SLC16A6 | 9120 | 2 | 5 | 63 | |
| GSE54994 | SLC16A6 | 9120 | 9 | 4 | 40 | |
| GSE60625 | SLC16A6 | 9120 | 4 | 2 | 5 | |
| GSE74703 | SLC16A6 | 9120 | 4 | 0 | 32 | |
| GSE74704 | SLC16A6 | 9120 | 3 | 2 | 15 | |
| TCGA | SLC16A6 | 9120 | 28 | 8 | 60 |
Total number of gains: 98; Total number of losses: 29; Total Number of normals: 361.
Somatic mutations of SLC16A6:
Generating mutation plots.
Highly correlated genes for SLC16A6:
Showing top 20/1903 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC16A6 | VSIG10L | 0.904374 | 6 | 0 | 6 |
| SLC16A6 | CYSRT1 | 0.903302 | 6 | 0 | 6 |
| SLC16A6 | SFTA2 | 0.899407 | 4 | 0 | 4 |
| SLC16A6 | SLURP1 | 0.896191 | 10 | 0 | 10 |
| SLC16A6 | ACPP | 0.891046 | 10 | 0 | 10 |
| SLC16A6 | TMPRSS11B | 0.886411 | 6 | 0 | 6 |
| SLC16A6 | SCNN1B | 0.881369 | 10 | 0 | 10 |
| SLC16A6 | CAPN14 | 0.880593 | 6 | 0 | 6 |
| SLC16A6 | SPINK7 | 0.880584 | 6 | 0 | 6 |
| SLC16A6 | GBP6 | 0.880332 | 4 | 0 | 4 |
| SLC16A6 | CXCR2 | 0.877465 | 11 | 0 | 11 |
| SLC16A6 | RANBP9 | 0.87513 | 11 | 0 | 11 |
| SLC16A6 | SASH1 | 0.871808 | 11 | 0 | 11 |
| SLC16A6 | GYS2 | 0.871769 | 10 | 0 | 10 |
| SLC16A6 | SPNS2 | 0.871643 | 5 | 0 | 5 |
| SLC16A6 | FCHO2 | 0.871083 | 7 | 0 | 7 |
| SLC16A6 | ULK3 | 0.869931 | 7 | 0 | 7 |
| SLC16A6 | UPK1A | 0.864631 | 10 | 0 | 10 |
| SLC16A6 | TGM3 | 0.864292 | 10 | 0 | 10 |
| SLC16A6 | SCEL | 0.863744 | 10 | 0 | 10 |
For details and further investigation, click here
