CRCT1

 

Full name: cysteine rich C-terminal 1 Alias Symbol: NICE-1
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 54544 HGNC ID: HGNC:29875 Ensembl Gene: ENSG00000169509 OMIM ID: 617426
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CRCT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CRCT1 54544 220620_at -4.2465 0.1023
GSE20347 CRCT1 54544 220620_at -5.4623 0.0000
GSE23400 CRCT1 54544 220620_at -4.0735 0.0000
GSE26886 CRCT1 54544 220620_at -7.5855 0.0000
GSE29001 CRCT1 54544 220620_at -4.8929 0.0000
GSE38129 CRCT1 54544 220620_at -4.1458 0.0000
GSE45670 CRCT1 54544 220620_at -1.5065 0.0216
GSE53622 CRCT1 54544 132442 -3.1614 0.0000
GSE53624 CRCT1 54544 132442 -3.6585 0.0000
GSE63941 CRCT1 54544 220620_at 0.4159 0.5910
GSE77861 CRCT1 54544 220620_at -2.6304 0.0038
GSE97050 CRCT1 54544 A_33_P3401295 -2.2261 0.1186
SRP007169 CRCT1 54544 RNAseq -9.7183 0.0000
SRP008496 CRCT1 54544 RNAseq -6.5867 0.0000
SRP064894 CRCT1 54544 RNAseq -6.0702 0.0000
SRP133303 CRCT1 54544 RNAseq -5.7536 0.0000
SRP159526 CRCT1 54544 RNAseq -6.5698 0.0000
SRP219564 CRCT1 54544 RNAseq -5.4673 0.0002
TCGA CRCT1 54544 RNAseq 0.4835 0.3925

Upregulated datasets: 0; Downregulated datasets: 15.  

 

Survival by CRCT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CRCT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CRCT1 54544 14 0 16
GSE20123 CRCT1 54544 14 0 16
GSE43470 CRCT1 54544 6 2 35
GSE46452 CRCT1 54544 2 1 56
GSE47630 CRCT1 54544 15 0 25
GSE54993 CRCT1 54544 0 4 66
GSE54994 CRCT1 54544 15 0 38
GSE60625 CRCT1 54544 0 0 11
GSE74703 CRCT1 54544 6 1 29
GSE74704 CRCT1 54544 7 0 13
TCGA CRCT1 54544 39 2 55

Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.  

 

Somatic mutations of CRCT1:

 

Generating mutation plots.

 

Highly correlated genes for CRCT1:

 

Showing top 20/1494 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CRCT1CYSRT10.913621606
CRCT1VSIG10L0.898697707
CRCT1ECM10.88784612012
CRCT1SCEL0.88736312012
CRCT1EMP10.88389411011
CRCT1TRIP100.88379410010
CRCT1TMPRSS11E0.88222511011
CRCT1SLURP10.88182912012
CRCT1GDPD30.87947212012
CRCT1SULT2B10.87944310010
CRCT1CSTB0.87765112012
CRCT1CNFN0.876561908
CRCT1RHCG0.87531413013
CRCT1ENDOU0.87507911011
CRCT1EPS8L10.87248512012
CRCT1NCCRP10.870899404
CRCT1TGM10.87040712012
CRCT1CLIC30.86916310010
CRCT1RAET1E0.869143707
CRCT1IL1RN0.86851412012

For details and further investigation, click here