| Full name: transmembrane protein 40 | Alias Symbol: FLJ11036 | ||
| Type: protein-coding gene | Cytoband: 3p25.2 | ||
| Entrez ID: 55287 | HGNC ID: HGNC:25620 | Ensembl Gene: ENSG00000088726 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM40:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM40 | 55287 | 222892_s_at | -1.7838 | 0.1140 | |
| GSE20347 | TMEM40 | 55287 | 219503_s_at | -1.4627 | 0.0000 | |
| GSE23400 | TMEM40 | 55287 | 219503_s_at | -1.0319 | 0.0000 | |
| GSE26886 | TMEM40 | 55287 | 222892_s_at | -3.3009 | 0.0000 | |
| GSE29001 | TMEM40 | 55287 | 219503_s_at | -1.4425 | 0.0001 | |
| GSE38129 | TMEM40 | 55287 | 219503_s_at | -0.8596 | 0.0212 | |
| GSE45670 | TMEM40 | 55287 | 222892_s_at | -0.7595 | 0.0401 | |
| GSE53622 | TMEM40 | 55287 | 104229 | -2.0970 | 0.0000 | |
| GSE53624 | TMEM40 | 55287 | 104229 | -3.1571 | 0.0000 | |
| GSE63941 | TMEM40 | 55287 | 222892_s_at | 2.6927 | 0.0201 | |
| GSE77861 | TMEM40 | 55287 | 222892_s_at | -1.9904 | 0.0007 | |
| GSE97050 | TMEM40 | 55287 | A_33_P3391418 | -0.2849 | 0.7288 | |
| SRP007169 | TMEM40 | 55287 | RNAseq | -5.4392 | 0.0000 | |
| SRP008496 | TMEM40 | 55287 | RNAseq | -5.1424 | 0.0000 | |
| SRP064894 | TMEM40 | 55287 | RNAseq | -3.8761 | 0.0000 | |
| SRP133303 | TMEM40 | 55287 | RNAseq | -2.2130 | 0.0000 | |
| SRP159526 | TMEM40 | 55287 | RNAseq | -3.6732 | 0.0000 | |
| SRP193095 | TMEM40 | 55287 | RNAseq | -2.7630 | 0.0000 | |
| SRP219564 | TMEM40 | 55287 | RNAseq | -3.4729 | 0.0019 | |
| TCGA | TMEM40 | 55287 | RNAseq | 1.6766 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 14.
Survival by TMEM40 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM40:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM40 | 55287 | 1 | 17 | 12 | |
| GSE20123 | TMEM40 | 55287 | 1 | 18 | 11 | |
| GSE43470 | TMEM40 | 55287 | 0 | 21 | 22 | |
| GSE46452 | TMEM40 | 55287 | 2 | 17 | 40 | |
| GSE47630 | TMEM40 | 55287 | 2 | 23 | 15 | |
| GSE54993 | TMEM40 | 55287 | 6 | 1 | 63 | |
| GSE54994 | TMEM40 | 55287 | 1 | 33 | 19 | |
| GSE60625 | TMEM40 | 55287 | 5 | 0 | 6 | |
| GSE74703 | TMEM40 | 55287 | 0 | 17 | 19 | |
| GSE74704 | TMEM40 | 55287 | 1 | 10 | 9 | |
| TCGA | TMEM40 | 55287 | 1 | 68 | 27 |
Total number of gains: 20; Total number of losses: 225; Total Number of normals: 243.
Somatic mutations of TMEM40:
Generating mutation plots.
Highly correlated genes for TMEM40:
Showing top 20/1651 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM40 | VSIG10L | 0.893842 | 7 | 0 | 7 |
| TMEM40 | SFTA2 | 0.889684 | 4 | 0 | 4 |
| TMEM40 | EVPL | 0.880635 | 12 | 0 | 12 |
| TMEM40 | TGM1 | 0.877395 | 12 | 0 | 12 |
| TMEM40 | ATG9B | 0.874471 | 7 | 0 | 7 |
| TMEM40 | EPGN | 0.872578 | 3 | 0 | 3 |
| TMEM40 | TMPRSS11E | 0.868637 | 11 | 0 | 11 |
| TMEM40 | ZNF185 | 0.865561 | 13 | 0 | 13 |
| TMEM40 | KRT78 | 0.862833 | 7 | 0 | 7 |
| TMEM40 | GDPD3 | 0.853562 | 12 | 0 | 12 |
| TMEM40 | GBP6 | 0.853341 | 4 | 0 | 4 |
| TMEM40 | A2ML1 | 0.852776 | 8 | 0 | 8 |
| TMEM40 | CYSRT1 | 0.851914 | 7 | 0 | 6 |
| TMEM40 | MAB21L3 | 0.851782 | 6 | 0 | 6 |
| TMEM40 | RAET1E | 0.849449 | 7 | 0 | 7 |
| TMEM40 | CWH43 | 0.848124 | 10 | 0 | 10 |
| TMEM40 | SPAG17 | 0.847093 | 5 | 0 | 5 |
| TMEM40 | TP53I3 | 0.846305 | 11 | 0 | 11 |
| TMEM40 | BTBD11 | 0.842364 | 7 | 0 | 7 |
| TMEM40 | MXD1 | 0.841169 | 12 | 0 | 12 |
For details and further investigation, click here
