| Full name: cell wall biogenesis 43 C-terminal homolog | Alias Symbol: FLJ21511|CWH43-C|PGAP2IP | ||
| Type: protein-coding gene | Cytoband: 4p11 | ||
| Entrez ID: 80157 | HGNC ID: HGNC:26133 | Ensembl Gene: ENSG00000109182 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CWH43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CWH43 | 80157 | 220723_s_at | -2.3207 | 0.2146 | |
| GSE20347 | CWH43 | 80157 | 220723_s_at | -3.4138 | 0.0000 | |
| GSE23400 | CWH43 | 80157 | 220723_s_at | -1.6945 | 0.0000 | |
| GSE26886 | CWH43 | 80157 | 220723_s_at | -4.8970 | 0.0000 | |
| GSE29001 | CWH43 | 80157 | 220723_s_at | -3.3900 | 0.0000 | |
| GSE38129 | CWH43 | 80157 | 220723_s_at | -2.7201 | 0.0000 | |
| GSE45670 | CWH43 | 80157 | 220723_s_at | -1.3284 | 0.0419 | |
| GSE53622 | CWH43 | 80157 | 106242 | -3.3751 | 0.0000 | |
| GSE53624 | CWH43 | 80157 | 106242 | -4.2662 | 0.0000 | |
| GSE63941 | CWH43 | 80157 | 220723_s_at | -0.0240 | 0.8800 | |
| GSE77861 | CWH43 | 80157 | 220723_s_at | -2.7664 | 0.0011 | |
| SRP007169 | CWH43 | 80157 | RNAseq | -6.8119 | 0.0000 | |
| SRP008496 | CWH43 | 80157 | RNAseq | -5.6959 | 0.0000 | |
| SRP064894 | CWH43 | 80157 | RNAseq | -3.5441 | 0.0000 | |
| SRP133303 | CWH43 | 80157 | RNAseq | -2.9696 | 0.0000 | |
| SRP159526 | CWH43 | 80157 | RNAseq | -6.0323 | 0.0000 | |
| SRP193095 | CWH43 | 80157 | RNAseq | -3.8715 | 0.0000 | |
| TCGA | CWH43 | 80157 | RNAseq | -0.4518 | 0.4367 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by CWH43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CWH43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CWH43 | 80157 | 3 | 14 | 13 | |
| GSE20123 | CWH43 | 80157 | 3 | 14 | 13 | |
| GSE43470 | CWH43 | 80157 | 0 | 14 | 29 | |
| GSE46452 | CWH43 | 80157 | 1 | 37 | 21 | |
| GSE47630 | CWH43 | 80157 | 1 | 18 | 21 | |
| GSE54993 | CWH43 | 80157 | 7 | 0 | 63 | |
| GSE54994 | CWH43 | 80157 | 3 | 10 | 40 | |
| GSE60625 | CWH43 | 80157 | 0 | 0 | 11 | |
| GSE74703 | CWH43 | 80157 | 0 | 12 | 24 | |
| GSE74704 | CWH43 | 80157 | 1 | 8 | 11 | |
| TCGA | CWH43 | 80157 | 21 | 34 | 41 |
Total number of gains: 40; Total number of losses: 161; Total Number of normals: 287.
Somatic mutations of CWH43:
Generating mutation plots.
Highly correlated genes for CWH43:
Showing top 20/1787 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CWH43 | CLIC3 | 0.893888 | 8 | 0 | 8 |
| CWH43 | ENDOU | 0.881457 | 10 | 0 | 10 |
| CWH43 | CRCT1 | 0.866896 | 10 | 0 | 10 |
| CWH43 | GDPD3 | 0.866813 | 10 | 0 | 10 |
| CWH43 | DHRS1 | 0.866295 | 10 | 0 | 10 |
| CWH43 | TMOD3 | 0.861702 | 10 | 0 | 10 |
| CWH43 | ECM1 | 0.859348 | 10 | 0 | 10 |
| CWH43 | ZNF185 | 0.856758 | 10 | 0 | 10 |
| CWH43 | SULT2B1 | 0.856258 | 8 | 0 | 8 |
| CWH43 | PTK6 | 0.855555 | 10 | 0 | 10 |
| CWH43 | CYSRT1 | 0.854153 | 6 | 0 | 6 |
| CWH43 | MXD1 | 0.854087 | 10 | 0 | 10 |
| CWH43 | TGM1 | 0.852288 | 10 | 0 | 10 |
| CWH43 | TP53I3 | 0.851944 | 10 | 0 | 10 |
| CWH43 | SCEL | 0.851332 | 10 | 0 | 10 |
| CWH43 | TMEM40 | 0.848124 | 10 | 0 | 10 |
| CWH43 | SPINK5 | 0.846809 | 10 | 0 | 10 |
| CWH43 | PRSS27 | 0.846001 | 6 | 0 | 6 |
| CWH43 | ALS2CL | 0.844951 | 10 | 0 | 10 |
| CWH43 | ACAA1 | 0.842827 | 8 | 0 | 8 |
For details and further investigation, click here
