| Full name: corticotropin releasing hormone binding protein | Alias Symbol: CRF-BP|CRFBP | ||
| Type: protein-coding gene | Cytoband: 5q13.3 | ||
| Entrez ID: 1393 | HGNC ID: HGNC:2356 | Ensembl Gene: ENSG00000145708 | OMIM ID: 122559 |
| Drug and gene relationship at DGIdb | |||
Expression of CRHBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRHBP | 1393 | 205984_at | -0.0257 | 0.9469 | |
| GSE20347 | CRHBP | 1393 | 205984_at | 0.0872 | 0.3380 | |
| GSE23400 | CRHBP | 1393 | 205984_at | -0.0663 | 0.1778 | |
| GSE26886 | CRHBP | 1393 | 205984_at | -0.0312 | 0.7772 | |
| GSE29001 | CRHBP | 1393 | 205984_at | 0.0517 | 0.7781 | |
| GSE38129 | CRHBP | 1393 | 205984_at | -0.0218 | 0.8272 | |
| GSE45670 | CRHBP | 1393 | 205984_at | -0.2300 | 0.0308 | |
| GSE53622 | CRHBP | 1393 | 51097 | -0.8578 | 0.0000 | |
| GSE53624 | CRHBP | 1393 | 51097 | 0.0327 | 0.8418 | |
| GSE63941 | CRHBP | 1393 | 205984_at | -0.3574 | 0.0130 | |
| GSE77861 | CRHBP | 1393 | 205984_at | -0.0250 | 0.8646 | |
| GSE97050 | CRHBP | 1393 | A_23_P30567 | -0.3562 | 0.3463 | |
| SRP133303 | CRHBP | 1393 | RNAseq | -1.3084 | 0.0000 | |
| TCGA | CRHBP | 1393 | RNAseq | -0.4913 | 0.3844 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CRHBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRHBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRHBP | 1393 | 1 | 13 | 16 | |
| GSE20123 | CRHBP | 1393 | 1 | 13 | 16 | |
| GSE43470 | CRHBP | 1393 | 1 | 13 | 29 | |
| GSE46452 | CRHBP | 1393 | 0 | 28 | 31 | |
| GSE47630 | CRHBP | 1393 | 1 | 19 | 20 | |
| GSE54993 | CRHBP | 1393 | 8 | 1 | 61 | |
| GSE54994 | CRHBP | 1393 | 1 | 19 | 33 | |
| GSE60625 | CRHBP | 1393 | 0 | 0 | 11 | |
| GSE74703 | CRHBP | 1393 | 1 | 9 | 26 | |
| GSE74704 | CRHBP | 1393 | 1 | 6 | 13 | |
| TCGA | CRHBP | 1393 | 5 | 49 | 42 |
Total number of gains: 20; Total number of losses: 170; Total Number of normals: 298.
Somatic mutations of CRHBP:
Generating mutation plots.
Highly correlated genes for CRHBP:
Showing top 20/654 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRHBP | ITPK1 | 0.768738 | 3 | 0 | 3 |
| CRHBP | PI16 | 0.720262 | 4 | 0 | 4 |
| CRHBP | PLIN4 | 0.715444 | 3 | 0 | 3 |
| CRHBP | SMTN | 0.710934 | 3 | 0 | 3 |
| CRHBP | CNTLN | 0.709323 | 4 | 0 | 3 |
| CRHBP | KAT7 | 0.706753 | 3 | 0 | 3 |
| CRHBP | KIR2DL2 | 0.705526 | 5 | 0 | 5 |
| CRHBP | IFNA5 | 0.70496 | 3 | 0 | 3 |
| CRHBP | MECP2 | 0.69824 | 3 | 0 | 3 |
| CRHBP | XKR4 | 0.69634 | 4 | 0 | 4 |
| CRHBP | ZNF358 | 0.696209 | 3 | 0 | 3 |
| CRHBP | RGS2 | 0.695359 | 3 | 0 | 3 |
| CRHBP | CADM2 | 0.694112 | 3 | 0 | 3 |
| CRHBP | SYDE1 | 0.684932 | 4 | 0 | 3 |
| CRHBP | CELF6 | 0.683115 | 3 | 0 | 3 |
| CRHBP | DNAJA1 | 0.68279 | 3 | 0 | 3 |
| CRHBP | ZNF334 | 0.682488 | 4 | 0 | 4 |
| CRHBP | ASB5 | 0.682156 | 4 | 0 | 4 |
| CRHBP | RHOJ | 0.673472 | 4 | 0 | 4 |
| CRHBP | DCHS2 | 0.673402 | 6 | 0 | 5 |
For details and further investigation, click here
