CADM2

 

Full name: cell adhesion molecule 2 Alias Symbol: NECL3|Necl-3|SynCAM2
Type: protein-coding gene Cytoband: 3p12.1
Entrez ID: 253559 HGNC ID: HGNC:29849 Ensembl Gene: ENSG00000175161 OMIM ID: 609938
Drug and gene relationship at DGIdb

 

Expression of CADM2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CADM2 253559 1552752_a_at -0.1015 0.8405
GSE26886 CADM2 253559 1555544_a_at -0.0701 0.5849
GSE45670 CADM2 253559 1552752_a_at -0.0715 0.3790
GSE53622 CADM2 253559 125184 -3.1065 0.0000
GSE53624 CADM2 253559 125184 -2.2741 0.0000
GSE63941 CADM2 253559 1555544_a_at 0.0117 0.9735
GSE77861 CADM2 253559 1555544_a_at -0.1679 0.2922
GSE97050 CADM2 253559 A_33_P3353210 -1.6908 0.1301
SRP064894 CADM2 253559 RNAseq -0.6260 0.2567
SRP133303 CADM2 253559 RNAseq -2.4096 0.0000
SRP159526 CADM2 253559 RNAseq -1.5142 0.0108
SRP219564 CADM2 253559 RNAseq -0.7245 0.4820
TCGA CADM2 253559 RNAseq -2.8413 0.0000

Upregulated datasets: 0; Downregulated datasets: 5.  


 

Survival by CADM2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CADM2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CADM2 253559 4 18 8
GSE20123 CADM2 253559 4 18 8
GSE43470 CADM2 253559 1 22 20
GSE46452 CADM2 253559 2 17 40
GSE47630 CADM2 253559 4 18 18
GSE54993 CADM2 253559 4 3 63
GSE54994 CADM2 253559 3 27 23
GSE60625 CADM2 253559 0 6 5
GSE74703 CADM2 253559 1 20 15
GSE74704 CADM2 253559 3 13 4
TCGA CADM2 253559 4 73 19

Total number of gains: 30; Total number of losses: 235; Total Number of normals: 223.  


 

Somatic mutations of CADM2:

 

Generating mutation plots.

 

Highly correlated genes for CADM2:

 

Showing top 20/658 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CADM2CYP21A20.858778303
CADM2SORCS10.844579404
CADM2SLITRK30.833916303
CADM2XKR40.828745404
CADM2PLAC90.815437404
CADM2RBFOX30.804762303
CADM2ANO50.80435404
CADM2CLEC3B0.803265303
CADM2ANKS1A0.800103303
CADM2ATP1B20.79847303
CADM2CAB39L0.784929303
CADM2BHMT20.781171404
CADM2PGR0.778807404
CADM2PYGM0.777631505
CADM2CTNNA30.776823505
CADM2TNXB0.769885303
CADM2AR0.769753303
CADM2SEMA3E0.768687303
CADM2SH3BGR0.765211404
CADM2TCEAL20.762798404

For details and further investigation, click here