| Full name: neurotensin receptor 2 | Alias Symbol: NTR2 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 23620 | HGNC ID: HGNC:8040 | Ensembl Gene: ENSG00000169006 | OMIM ID: 605538 |
| Drug and gene relationship at DGIdb | |||
Expression of NTSR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NTSR2 | 23620 | 206899_at | 0.2363 | 0.3351 | |
| GSE20347 | NTSR2 | 23620 | 206899_at | 0.0229 | 0.8324 | |
| GSE23400 | NTSR2 | 23620 | 206899_at | -0.0727 | 0.1105 | |
| GSE26886 | NTSR2 | 23620 | 206899_at | 0.0809 | 0.5352 | |
| GSE29001 | NTSR2 | 23620 | 206899_at | 0.0241 | 0.9147 | |
| GSE38129 | NTSR2 | 23620 | 206899_at | -0.0691 | 0.4501 | |
| GSE45670 | NTSR2 | 23620 | 206899_at | 0.3185 | 0.0001 | |
| GSE53622 | NTSR2 | 23620 | 44180 | 0.0028 | 0.9790 | |
| GSE53624 | NTSR2 | 23620 | 44180 | 0.1604 | 0.0348 | |
| GSE63941 | NTSR2 | 23620 | 206899_at | 0.1044 | 0.5710 | |
| GSE77861 | NTSR2 | 23620 | 206899_at | -0.0192 | 0.8742 | |
| TCGA | NTSR2 | 23620 | RNAseq | 1.5260 | 0.2082 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NTSR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NTSR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NTSR2 | 23620 | 10 | 2 | 18 | |
| GSE20123 | NTSR2 | 23620 | 10 | 2 | 18 | |
| GSE43470 | NTSR2 | 23620 | 2 | 1 | 40 | |
| GSE46452 | NTSR2 | 23620 | 3 | 4 | 52 | |
| GSE47630 | NTSR2 | 23620 | 7 | 0 | 33 | |
| GSE54993 | NTSR2 | 23620 | 0 | 7 | 63 | |
| GSE54994 | NTSR2 | 23620 | 11 | 0 | 42 | |
| GSE60625 | NTSR2 | 23620 | 0 | 3 | 8 | |
| GSE74703 | NTSR2 | 23620 | 2 | 0 | 34 | |
| GSE74704 | NTSR2 | 23620 | 9 | 1 | 10 | |
| TCGA | NTSR2 | 23620 | 34 | 5 | 57 |
Total number of gains: 88; Total number of losses: 25; Total Number of normals: 375.
Somatic mutations of NTSR2:
Generating mutation plots.
Highly correlated genes for NTSR2:
Showing top 20/698 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NTSR2 | NTNG1 | 0.719273 | 4 | 0 | 4 |
| NTSR2 | CRHR2 | 0.715838 | 4 | 0 | 4 |
| NTSR2 | BRS3 | 0.705422 | 3 | 0 | 3 |
| NTSR2 | DAB1 | 0.705154 | 4 | 0 | 4 |
| NTSR2 | TFEB | 0.703715 | 3 | 0 | 3 |
| NTSR2 | MAS1 | 0.702847 | 4 | 0 | 4 |
| NTSR2 | TAF1 | 0.699103 | 3 | 0 | 3 |
| NTSR2 | ERN1 | 0.695337 | 3 | 0 | 3 |
| NTSR2 | NEU3 | 0.69135 | 4 | 0 | 4 |
| NTSR2 | NUDT7 | 0.686803 | 3 | 0 | 3 |
| NTSR2 | PRAMEF12 | 0.684123 | 4 | 0 | 4 |
| NTSR2 | IFNA17 | 0.680762 | 4 | 0 | 4 |
| NTSR2 | KIF17 | 0.680193 | 4 | 0 | 4 |
| NTSR2 | LINC01010 | 0.680096 | 3 | 0 | 3 |
| NTSR2 | AGAP2 | 0.676442 | 4 | 0 | 4 |
| NTSR2 | PKLR | 0.671149 | 4 | 0 | 3 |
| NTSR2 | SYN1 | 0.670715 | 5 | 0 | 4 |
| NTSR2 | P2RY4 | 0.669133 | 4 | 0 | 4 |
| NTSR2 | SCN10A | 0.667174 | 3 | 0 | 3 |
| NTSR2 | NPFFR1 | 0.665382 | 6 | 0 | 6 |
For details and further investigation, click here
