| Full name: nuclear receptor subfamily 6 group A member 1 | Alias Symbol: GCNF1|RTR|CT150 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 2649 | HGNC ID: HGNC:7985 | Ensembl Gene: ENSG00000148200 | OMIM ID: 602778 |
| Drug and gene relationship at DGIdb | |||
Expression of NR6A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR6A1 | 2649 | 227494_at | -0.0164 | 0.9700 | |
| GSE20347 | NR6A1 | 2649 | 210391_at | -0.1209 | 0.2991 | |
| GSE23400 | NR6A1 | 2649 | 210391_at | -0.1937 | 0.0000 | |
| GSE26886 | NR6A1 | 2649 | 227494_at | -0.1395 | 0.1954 | |
| GSE29001 | NR6A1 | 2649 | 210391_at | -0.2798 | 0.1976 | |
| GSE38129 | NR6A1 | 2649 | 211402_x_at | -0.1131 | 0.3124 | |
| GSE45670 | NR6A1 | 2649 | 227494_at | 0.0138 | 0.9175 | |
| GSE53622 | NR6A1 | 2649 | 2832 | -0.4845 | 0.0078 | |
| GSE53624 | NR6A1 | 2649 | 2832 | -0.2455 | 0.0193 | |
| GSE63941 | NR6A1 | 2649 | 228894_at | 1.1347 | 0.0138 | |
| GSE77861 | NR6A1 | 2649 | 210392_x_at | -0.1625 | 0.0836 | |
| GSE97050 | NR6A1 | 2649 | A_33_P3659678 | -0.1791 | 0.4342 | |
| SRP007169 | NR6A1 | 2649 | RNAseq | -0.6282 | 0.2981 | |
| SRP064894 | NR6A1 | 2649 | RNAseq | -0.1761 | 0.5280 | |
| SRP133303 | NR6A1 | 2649 | RNAseq | -0.2312 | 0.2630 | |
| SRP159526 | NR6A1 | 2649 | RNAseq | -0.4093 | 0.1830 | |
| SRP193095 | NR6A1 | 2649 | RNAseq | -0.2187 | 0.2283 | |
| SRP219564 | NR6A1 | 2649 | RNAseq | -0.3293 | 0.5549 | |
| TCGA | NR6A1 | 2649 | RNAseq | 0.7144 | 0.0020 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NR6A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR6A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR6A1 | 2649 | 4 | 8 | 18 | |
| GSE20123 | NR6A1 | 2649 | 4 | 8 | 18 | |
| GSE43470 | NR6A1 | 2649 | 6 | 4 | 33 | |
| GSE46452 | NR6A1 | 2649 | 6 | 13 | 40 | |
| GSE47630 | NR6A1 | 2649 | 3 | 16 | 21 | |
| GSE54993 | NR6A1 | 2649 | 3 | 3 | 64 | |
| GSE54994 | NR6A1 | 2649 | 10 | 10 | 33 | |
| GSE60625 | NR6A1 | 2649 | 0 | 0 | 11 | |
| GSE74703 | NR6A1 | 2649 | 5 | 3 | 28 | |
| GSE74704 | NR6A1 | 2649 | 2 | 6 | 12 | |
| TCGA | NR6A1 | 2649 | 27 | 25 | 44 |
Total number of gains: 70; Total number of losses: 96; Total Number of normals: 322.
Somatic mutations of NR6A1:
Generating mutation plots.
Highly correlated genes for NR6A1:
Showing top 20/895 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR6A1 | MTAP | 0.733353 | 5 | 0 | 5 |
| NR6A1 | CACNA1H | 0.728141 | 3 | 0 | 3 |
| NR6A1 | CRHR2 | 0.721719 | 4 | 0 | 4 |
| NR6A1 | C6 | 0.720764 | 4 | 0 | 4 |
| NR6A1 | LIPC | 0.712688 | 4 | 0 | 4 |
| NR6A1 | SHOX | 0.705057 | 4 | 0 | 4 |
| NR6A1 | TREH | 0.700946 | 3 | 0 | 3 |
| NR6A1 | GABRR2 | 0.699936 | 4 | 0 | 4 |
| NR6A1 | BMP15 | 0.694585 | 5 | 0 | 5 |
| NR6A1 | MAPK8 | 0.691377 | 3 | 0 | 3 |
| NR6A1 | APOM | 0.678643 | 4 | 0 | 4 |
| NR6A1 | OR2H2 | 0.673817 | 6 | 0 | 6 |
| NR6A1 | OR2F2 | 0.670973 | 3 | 0 | 3 |
| NR6A1 | CAMK2A | 0.670718 | 3 | 0 | 3 |
| NR6A1 | OPCML | 0.670143 | 4 | 0 | 4 |
| NR6A1 | MVK | 0.669613 | 9 | 0 | 8 |
| NR6A1 | ELSPBP1 | 0.668374 | 5 | 0 | 5 |
| NR6A1 | ZNF287 | 0.66801 | 4 | 0 | 3 |
| NR6A1 | PRTN3 | 0.665788 | 3 | 0 | 3 |
| NR6A1 | GML | 0.661269 | 7 | 0 | 6 |
For details and further investigation, click here
