| Full name: uroplakin 3B | Alias Symbol: MGC10902|p35|UPIIIb|FLJ32198 | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 105375355 | HGNC ID: HGNC:21444 | Ensembl Gene: ENSG00000243566 | OMIM ID: 611887 |
| Drug and gene relationship at DGIdb | |||
Expression of UPK3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | UPK3B | 105375355 | 14338 | -3.3573 | 0.0000 | |
| GSE53624 | UPK3B | 105375355 | 14338 | -3.9621 | 0.0000 | |
| GSE97050 | UPK3B | A_21_P0013246 | -0.4686 | 0.4119 | ||
| SRP007169 | UPK3B | 105375355 | RNAseq | -4.4774 | 0.0000 | |
| SRP008496 | UPK3B | 105375355 | RNAseq | -4.8787 | 0.0000 | |
| SRP064894 | UPK3B | 105375355 | RNAseq | -4.2037 | 0.0000 | |
| SRP133303 | UPK3B | 105375355 | RNAseq | -3.1839 | 0.0000 | |
| SRP159526 | UPK3B | 105375355 | RNAseq | -4.1967 | 0.0000 | |
| SRP193095 | UPK3B | 105375355 | RNAseq | -2.4794 | 0.0000 | |
| SRP219564 | UPK3B | 105375355 | RNAseq | -4.1825 | 0.0000 | |
| TCGA | UPK3B | 105375355 | RNAseq | -0.0006 | 0.9987 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by UPK3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UPK3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UPK3B | 80761 | 15 | 1 | 14 | |
| GSE20123 | UPK3B | 80761 | 15 | 1 | 14 | |
| GSE43470 | UPK3B | 80761 | 3 | 2 | 38 | |
| GSE46452 | UPK3B | 80761 | 11 | 0 | 48 | |
| GSE47630 | UPK3B | 80761 | 7 | 3 | 30 | |
| GSE54993 | UPK3B | 80761 | 2 | 7 | 61 | |
| GSE54994 | UPK3B | 80761 | 15 | 3 | 35 | |
| GSE60625 | UPK3B | 80761 | 0 | 0 | 11 | |
| GSE74703 | UPK3B | 80761 | 3 | 1 | 32 | |
| GSE74704 | UPK3B | 80761 | 8 | 1 | 11 | |
| TCGA | UPK3B | 80761 | 44 | 5 | 47 |
Total number of gains: 123; Total number of losses: 24; Total Number of normals: 341.
Somatic mutations of UPK3B:
Generating mutation plots.
Highly correlated genes for UPK3B:
Showing top 20/494 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UPK3B | IKZF2 | 0.890958 | 3 | 0 | 3 |
| UPK3B | DHRS1 | 0.875485 | 3 | 0 | 3 |
| UPK3B | LMO7 | 0.872533 | 3 | 0 | 3 |
| UPK3B | EXPH5 | 0.868823 | 3 | 0 | 3 |
| UPK3B | HS3ST6 | 0.859919 | 3 | 0 | 3 |
| UPK3B | KAZN | 0.856411 | 3 | 0 | 3 |
| UPK3B | SCNN1B | 0.852345 | 3 | 0 | 3 |
| UPK3B | CLCA4 | 0.851915 | 3 | 0 | 3 |
| UPK3B | FAM3D | 0.847253 | 3 | 0 | 3 |
| UPK3B | VSIG10L | 0.846317 | 3 | 0 | 3 |
| UPK3B | HOPX | 0.845801 | 3 | 0 | 3 |
| UPK3B | TMPRSS11E | 0.844925 | 3 | 0 | 3 |
| UPK3B | ENDOU | 0.8438 | 3 | 0 | 3 |
| UPK3B | IL36A | 0.842797 | 3 | 0 | 3 |
| UPK3B | LPIN1 | 0.842371 | 3 | 0 | 3 |
| UPK3B | PPL | 0.841199 | 3 | 0 | 3 |
| UPK3B | ZDHHC13 | 0.839433 | 3 | 0 | 3 |
| UPK3B | YOD1 | 0.838305 | 3 | 0 | 3 |
| UPK3B | C1orf116 | 0.837262 | 3 | 0 | 3 |
| UPK3B | FUT3 | 0.835677 | 3 | 0 | 3 |
For details and further investigation, click here
