| Full name: retinal G protein coupled receptor | Alias Symbol: RP44 | ||
| Type: protein-coding gene | Cytoband: 10q23.1 | ||
| Entrez ID: 5995 | HGNC ID: HGNC:9990 | Ensembl Gene: ENSG00000148604 | OMIM ID: 600342 |
| Drug and gene relationship at DGIdb | |||
Expression of RGR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGR | 5995 | 1555219_at | -0.1217 | 0.5596 | |
| GSE20347 | RGR | 5995 | 207070_at | -0.0339 | 0.7047 | |
| GSE23400 | RGR | 5995 | 207070_at | -0.1684 | 0.0000 | |
| GSE26886 | RGR | 5995 | 207070_at | 0.1717 | 0.2317 | |
| GSE29001 | RGR | 5995 | 207070_at | -0.1712 | 0.2403 | |
| GSE38129 | RGR | 5995 | 207070_at | -0.1548 | 0.0413 | |
| GSE45670 | RGR | 5995 | 1555219_at | 0.0038 | 0.9727 | |
| GSE53622 | RGR | 5995 | 5960 | 0.1735 | 0.0481 | |
| GSE53624 | RGR | 5995 | 5960 | 0.1003 | 0.3321 | |
| GSE63941 | RGR | 5995 | 1555219_at | 0.1313 | 0.2843 | |
| GSE77861 | RGR | 5995 | 207070_at | -0.0827 | 0.3468 | |
| GSE97050 | RGR | 5995 | A_24_P289273 | 0.1474 | 0.4962 | |
| SRP133303 | RGR | 5995 | RNAseq | 0.0469 | 0.7014 | |
| SRP193095 | RGR | 5995 | RNAseq | 0.2520 | 0.1631 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RGR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGR | 5995 | 1 | 6 | 23 | |
| GSE20123 | RGR | 5995 | 1 | 5 | 24 | |
| GSE43470 | RGR | 5995 | 1 | 6 | 36 | |
| GSE46452 | RGR | 5995 | 0 | 11 | 48 | |
| GSE47630 | RGR | 5995 | 2 | 14 | 24 | |
| GSE54993 | RGR | 5995 | 7 | 0 | 63 | |
| GSE54994 | RGR | 5995 | 1 | 12 | 40 | |
| GSE60625 | RGR | 5995 | 0 | 0 | 11 | |
| GSE74703 | RGR | 5995 | 1 | 4 | 31 | |
| GSE74704 | RGR | 5995 | 0 | 3 | 17 | |
| TCGA | RGR | 5995 | 9 | 25 | 62 |
Total number of gains: 23; Total number of losses: 86; Total Number of normals: 379.
Somatic mutations of RGR:
Generating mutation plots.
Highly correlated genes for RGR:
Showing top 20/1230 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGR | CSH2 | 0.799507 | 3 | 0 | 3 |
| RGR | PTPRN2 | 0.773529 | 4 | 0 | 4 |
| RGR | STRC | 0.749911 | 3 | 0 | 3 |
| RGR | ABCC6 | 0.735848 | 4 | 0 | 4 |
| RGR | PPP1R3F | 0.723021 | 3 | 0 | 3 |
| RGR | C1QL2 | 0.722751 | 3 | 0 | 3 |
| RGR | LY6G6C | 0.720627 | 4 | 0 | 3 |
| RGR | LRRC10 | 0.718807 | 3 | 0 | 3 |
| RGR | PLA2G6 | 0.712091 | 5 | 0 | 5 |
| RGR | DIO2 | 0.71014 | 3 | 0 | 3 |
| RGR | BRINP2 | 0.703222 | 4 | 0 | 4 |
| RGR | KRTAP5-9 | 0.702941 | 4 | 0 | 4 |
| RGR | MAP3K19 | 0.701326 | 4 | 0 | 4 |
| RGR | HTR4 | 0.700802 | 5 | 0 | 4 |
| RGR | KCNQ1DN | 0.700551 | 6 | 0 | 6 |
| RGR | SLC10A1 | 0.699557 | 7 | 0 | 6 |
| RGR | CACFD1 | 0.698915 | 5 | 0 | 5 |
| RGR | DUX1 | 0.69802 | 6 | 0 | 6 |
| RGR | GPR152 | 0.697738 | 3 | 0 | 3 |
| RGR | PRB1 | 0.692543 | 5 | 0 | 4 |
For details and further investigation, click here
