| Full name: SH2 domain containing 1A | Alias Symbol: XLP|MTCP1|DSHP|XLPD|EBVS|SAP | ||
| Type: protein-coding gene | Cytoband: Xq25 | ||
| Entrez ID: 4068 | HGNC ID: HGNC:10820 | Ensembl Gene: ENSG00000183918 | OMIM ID: 300490 |
| Drug and gene relationship at DGIdb | |||
SH2D1A involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04650 | Natural killer cell mediated cytotoxicity | |
| hsa05162 | Measles |
Expression of SH2D1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH2D1A | 4068 | 211210_x_at | 0.1268 | 0.8306 | |
| GSE20347 | SH2D1A | 4068 | 211210_x_at | -0.0961 | 0.3318 | |
| GSE23400 | SH2D1A | 4068 | 211209_x_at | -0.0817 | 0.0893 | |
| GSE26886 | SH2D1A | 4068 | 211210_x_at | -0.1905 | 0.1802 | |
| GSE29001 | SH2D1A | 4068 | 211210_x_at | -0.1705 | 0.2629 | |
| GSE38129 | SH2D1A | 4068 | 211210_x_at | -0.0696 | 0.4595 | |
| GSE45670 | SH2D1A | 4068 | 211210_x_at | 0.1140 | 0.3487 | |
| GSE53622 | SH2D1A | 4068 | 49354 | -0.1028 | 0.6667 | |
| GSE53624 | SH2D1A | 4068 | 49354 | -0.2536 | 0.2395 | |
| GSE63941 | SH2D1A | 4068 | 211210_x_at | 0.1426 | 0.2777 | |
| GSE77861 | SH2D1A | 4068 | 211210_x_at | -0.2045 | 0.1238 | |
| GSE97050 | SH2D1A | 4068 | A_24_P203103 | 0.0346 | 0.8962 | |
| SRP133303 | SH2D1A | 4068 | RNAseq | -0.1335 | 0.7184 | |
| SRP219564 | SH2D1A | 4068 | RNAseq | 0.4698 | 0.5194 | |
| TCGA | SH2D1A | 4068 | RNAseq | -0.0167 | 0.9584 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SH2D1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH2D1A:
No record found for this gene.
Somatic mutations of SH2D1A:
Generating mutation plots.
Highly correlated genes for SH2D1A:
Showing top 20/478 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH2D1A | IL10RA | 0.686234 | 7 | 0 | 6 |
| SH2D1A | GIMAP2 | 0.682105 | 4 | 0 | 4 |
| SH2D1A | MAGEA8 | 0.675228 | 3 | 0 | 3 |
| SH2D1A | CPA2 | 0.674784 | 4 | 0 | 4 |
| SH2D1A | CRLF2 | 0.671849 | 3 | 0 | 3 |
| SH2D1A | SNCB | 0.662139 | 3 | 0 | 3 |
| SH2D1A | CTSE | 0.660513 | 3 | 0 | 3 |
| SH2D1A | KLHL35 | 0.656601 | 4 | 0 | 4 |
| SH2D1A | DTHD1 | 0.653535 | 4 | 0 | 3 |
| SH2D1A | PRRG3 | 0.650497 | 3 | 0 | 3 |
| SH2D1A | PLCL2 | 0.650085 | 5 | 0 | 4 |
| SH2D1A | RCSD1 | 0.648944 | 5 | 0 | 3 |
| SH2D1A | EOMES | 0.647267 | 4 | 0 | 3 |
| SH2D1A | MPEG1 | 0.647204 | 3 | 0 | 3 |
| SH2D1A | NGB | 0.645363 | 5 | 0 | 4 |
| SH2D1A | CYTIP | 0.637429 | 4 | 0 | 3 |
| SH2D1A | KIF25 | 0.635733 | 7 | 0 | 6 |
| SH2D1A | SLA | 0.635153 | 6 | 0 | 5 |
| SH2D1A | OR10H2 | 0.634011 | 4 | 0 | 3 |
| SH2D1A | GPR15 | 0.631192 | 6 | 0 | 4 |
For details and further investigation, click here
