| Full name: transportin 1 | Alias Symbol: MIP|TRN|IPO2|MIP1 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 3842 | HGNC ID: HGNC:6401 | Ensembl Gene: ENSG00000083312 | OMIM ID: 602901 |
Screen Evidence:
| |||
Expression of TNPO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNPO1 | 3842 | 221829_s_at | 0.3458 | 0.4730 | |
| GSE20347 | TNPO1 | 3842 | 221829_s_at | 0.3748 | 0.0034 | |
| GSE23400 | TNPO1 | 3842 | 221829_s_at | 0.3484 | 0.0033 | |
| GSE26886 | TNPO1 | 3842 | 221829_s_at | 0.4478 | 0.0090 | |
| GSE29001 | TNPO1 | 3842 | 221829_s_at | 0.2105 | 0.5756 | |
| GSE38129 | TNPO1 | 3842 | 221829_s_at | 0.2822 | 0.0749 | |
| GSE45670 | TNPO1 | 3842 | 221829_s_at | 0.3744 | 0.0095 | |
| GSE53622 | TNPO1 | 3842 | 127831 | 0.1718 | 0.0031 | |
| GSE53624 | TNPO1 | 3842 | 32514 | 0.0539 | 0.3566 | |
| GSE63941 | TNPO1 | 3842 | 221829_s_at | -0.1764 | 0.7277 | |
| GSE77861 | TNPO1 | 3842 | 221829_s_at | 0.7687 | 0.0185 | |
| GSE97050 | TNPO1 | A_21_P0011577 | 0.2050 | 0.3973 | ||
| SRP007169 | TNPO1 | 3842 | RNAseq | 0.4691 | 0.2086 | |
| SRP008496 | TNPO1 | 3842 | RNAseq | 0.5876 | 0.0349 | |
| SRP064894 | TNPO1 | 3842 | RNAseq | 0.0677 | 0.7177 | |
| SRP133303 | TNPO1 | 3842 | RNAseq | 0.1602 | 0.2637 | |
| SRP159526 | TNPO1 | 3842 | RNAseq | 0.3407 | 0.3534 | |
| SRP193095 | TNPO1 | 3842 | RNAseq | 0.1165 | 0.3323 | |
| SRP219564 | TNPO1 | 3842 | RNAseq | -0.1789 | 0.5258 | |
| TCGA | TNPO1 | 3842 | RNAseq | -0.0134 | 0.7740 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNPO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNPO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNPO1 | 3842 | 1 | 13 | 16 | |
| GSE20123 | TNPO1 | 3842 | 1 | 13 | 16 | |
| GSE43470 | TNPO1 | 3842 | 1 | 13 | 29 | |
| GSE46452 | TNPO1 | 3842 | 0 | 28 | 31 | |
| GSE47630 | TNPO1 | 3842 | 1 | 19 | 20 | |
| GSE54993 | TNPO1 | 3842 | 8 | 1 | 61 | |
| GSE54994 | TNPO1 | 3842 | 1 | 19 | 33 | |
| GSE60625 | TNPO1 | 3842 | 0 | 0 | 11 | |
| GSE74703 | TNPO1 | 3842 | 1 | 9 | 26 | |
| GSE74704 | TNPO1 | 3842 | 1 | 6 | 13 | |
| TCGA | TNPO1 | 3842 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of TNPO1:
Generating mutation plots.
Highly correlated genes for TNPO1:
Showing top 20/838 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNPO1 | TRIM35 | 0.790932 | 3 | 0 | 3 |
| TNPO1 | MEGF6 | 0.787318 | 3 | 0 | 3 |
| TNPO1 | PIEZO1 | 0.777813 | 4 | 0 | 4 |
| TNPO1 | CRYBB2 | 0.77235 | 3 | 0 | 3 |
| TNPO1 | SNRNP48 | 0.75495 | 3 | 0 | 3 |
| TNPO1 | WDR75 | 0.754231 | 5 | 0 | 5 |
| TNPO1 | RRAS2 | 0.751608 | 3 | 0 | 3 |
| TNPO1 | MAPK8IP3 | 0.750638 | 3 | 0 | 3 |
| TNPO1 | TMEM237 | 0.741564 | 3 | 0 | 3 |
| TNPO1 | NOP58 | 0.73868 | 5 | 0 | 5 |
| TNPO1 | QPCTL | 0.738123 | 3 | 0 | 3 |
| TNPO1 | MIER2 | 0.728264 | 4 | 0 | 4 |
| TNPO1 | CDCA3 | 0.714453 | 3 | 0 | 3 |
| TNPO1 | TTL | 0.713364 | 4 | 0 | 4 |
| TNPO1 | SZT2 | 0.7114 | 3 | 0 | 3 |
| TNPO1 | SRA1 | 0.709202 | 3 | 0 | 3 |
| TNPO1 | KHNYN | 0.708178 | 4 | 0 | 3 |
| TNPO1 | EFHD2 | 0.708157 | 3 | 0 | 3 |
| TNPO1 | SAG | 0.708039 | 5 | 0 | 5 |
| TNPO1 | PIF1 | 0.707567 | 3 | 0 | 3 |
For details and further investigation, click here
